Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Carol L. Zielke"'
Publikováno v:
Journal of Neurochemistry. 101:9-16
Glucose is the primary carbon source to enter the adult brain for catabolic and anabolic reactions. Some studies suggest that astrocytes may metabolize glucose to lactate; the latter serving as a preferential substrate for neurons, especially during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c486475696bb3959d9982b6b0f4de261
https://doi.org/10.1111/j.1471-4159.2006.04335.x
https://doi.org/10.1111/j.1471-4159.2006.04335.x
Publikováno v:
Journal of Neuroscience Research. 85:3145-3149
The oxidative capacity of the brain for alternate substrates, glucose, lactate, pyruvate, acetate, glutamate, and glutamine was determined by using microdialysis to infuse 14C-labeled compounds into the interstitial fluid of adult rat brain and by co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1859a76e7bc294bae132eaf2bec67170
https://doi.org/10.1002/jnr.21424
https://doi.org/10.1002/jnr.21424
Publikováno v:
Genomics. 81:457-467
Down syndrome (DS) results from complete or partial triplication of human chromosome 21. It is assumed that the neurological and other symptoms are caused by the overexpression of genes on chromosome 21, but this hypothesis has not yet been assessed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d3593401e18b6f7ab35aa11cbb2332
https://doi.org/10.1016/s0888-7543(03)00035-1
https://doi.org/10.1016/s0888-7543(03)00035-1
Autor:
L. A. Martin, Robert J. Bloch, Tessa Chaney, Wendy G. Resneck, Bradley E. Alger, Jeanine A. Ursitti, Carol L. Zielke
Publikováno v:
Developmental Brain Research. 129:81-93
We studied the spectrins in developing hippocampal tissue in vivo and in vitro to learn how they contribute to the organization of synaptic and extrasynaptic regions of the neuronal plasma membrane. beta-Spectrin, but not beta-fodrin or alpha-fodrin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ab3de2fa74498dba31a59247c16f68
https://doi.org/10.1016/s0165-3806(01)00160-2
https://doi.org/10.1016/s0165-3806(01)00160-2
Publikováno v:
Journal of Neuroscience Research. 60:632-641
Hydrolysis of extracellular glutamine as a potential source of increased extracellular glutamate in the quinolinic acid (QUIN)-injured brain of the unanesthetized, free-moving rat was examined by microdialysis and HPLC analysis. Injury was initiated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a372bf194345d6620bbd309465e58be3
https://doi.org/10.1002/(sici)1097-4547(20000601)60:5<632::aid-jnr8>3.0.co
https://doi.org/10.1002/(sici)1097-4547(20000601)60:5<632::aid-jnr8>3.0.co
Autor:
Carol L. Zielke, Irene B. Hopkins, Xueli Huang, J. Tyson Tildon, Mary C. McKenna, Joseph H. Stevenson
Publikováno v:
Neurochemistry International. 36:451-459
Most of the malic enzyme activity in the brain is found in the mitochondria. This isozyme may have a key role in the pyruvate recycling pathway which utilizes dicarboxylic acids and substrates such as glutamine to provide pyruvate to maintain TCA cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9121902eab15987247de1499e90b2f38
https://doi.org/10.1016/s0197-0186(99)00148-5
https://doi.org/10.1016/s0197-0186(99)00148-5
Publikováno v:
Neurochemical Research. 22:1159-1164
Leucine and α-ketoisocaproate (α-KIC) were perfused at increasing concentrations into rat brain hippocampus by microdialysis to mimic the conditions of maple syrup urine disease. The effects of elevated leucine or α-KIC on the oxidation of L-[U-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe928db3d4506db5238a44ffb6f44583
https://doi.org/10.1023/a:1027325620983
https://doi.org/10.1023/a:1027325620983
Publikováno v:
Neurochemical Research. 21:1161-1165
Arginine is an intermediate in the elimination of excess nitrogen and is the substrate for nitric oxide synthesis. Arginine synthesis has been reported in brain tissue. We have studied the activity of the arginine biosynthetic enzymes argininosuccina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f89e3b5694135ba2d389fa78c03d079
https://doi.org/10.1007/bf02532390
https://doi.org/10.1007/bf02532390
Publikováno v:
Developmental Neuroscience. 18:415-419
A microenvironment similar to that found in maple syrup urine disease was created in the brain of free-moving, awake rats by the infusion of leucine into the brain using microdialysis. To determine the effects on amino acid homeostasis the eluate of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2841d2abfa1c6f5fc0eb066d767d3f
https://doi.org/10.1159/000111435
https://doi.org/10.1159/000111435
Publikováno v:
Developmental Neuroscience. 18:224-230
The rate of glutaminase-dependent metabolism of glutamine in intact astrocytes was determined under conditions in which the extracellular concentration of glutamine was varied between 0.2 and 3.2 mM glutamine for control and dibutyryl cyclic AMP (dBc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72ac4111b100c045edd2e935fb8ff04
https://doi.org/10.1159/000111410
https://doi.org/10.1159/000111410