Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Carol L. Zablotny"'
Autor:
Mary Sue Marty, Adam W. Perala, Shakil A. Saghir, Larry Hammond, James S. Bus, Carol L. Zablotny, Barbara H. Neal, Julie K. Passage
Publikováno v:
Toxicological Sciences
Life-stage-dependent toxicity and dose-dependent toxicokinetics (TK) were evaluated in Sprague Dawley rats following dietary exposure to 2,4-dichlorophenoxyacetic acid (2,4-D). 2,4-D renal clearance is impacted by dose-dependent saturation of the ren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fddc57e72370715395808fa3d7e6f43
https://doi.org/10.1093/toxsci/kft212
https://doi.org/10.1093/toxsci/kft212
Autor:
Kamin J. Johnson, Nicholas Ball, Carol L. Zablotny, Sue Marty, Amanda K. Andrus, Bethany R. Hannas, Jessica LaRocca
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781493972067
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d012f653435225be91346efb5edfd3e
https://doi.org/10.1007/7653_2016_65
https://doi.org/10.1007/7653_2016_65
Publikováno v:
Regulatory Toxicology and Pharmacology. 62:496-503
The biocide diiodomethyl-p-tolylsulfone (DIMPTS) caused dystocia, decreased neonatal survival and hypothyroidism in rat reproduction studies resembling the effects caused by iodine. One molecule of DIMPTS contains two iodine moieties that are hydroly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6e663b0cb84542915031a7e28b2f1f
https://doi.org/10.1016/j.yrtph.2011.10.010
https://doi.org/10.1016/j.yrtph.2011.10.010
Autor:
Toby Collins, Edward W. Carney, Valerie A. Marshall, Carol L. Zablotny, Reza J. Rasoulpour, Neil S. Millar, Claire Terry, Alasdair J. Gibb, Richard Billington, Robert G. Ellis-Hutchings
Publikováno v:
Toxicological Sciences. 127:522-534
Sulfoxaflor (X11422208), a novel agricultural molecule, induced fetal effects (forelimb flexure, hindlimb rotation, and bent clavicle) and neonatal death in rats at high doses (≥ 400 ppm in diet); however, no such effects occurred in rabbit dietary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58af7d2a61202dbe858cbec2d5ccbf9e
https://doi.org/10.1093/toxsci/kfs118
https://doi.org/10.1093/toxsci/kfs118
Autor:
Phyllis K. Anderson, E. W. Carney, Mary Sue Marty, J. W. Crissman, Carol L. Zablotny, Michael R. Woolhiser, Michael P. Holsapple
Publikováno v:
Toxicological Sciences. 82:237-249
This study determined the effects of feed restriction (FR) during in utero and postnatal life on standard reproductive toxicity and developmental immunotoxicity end points. Groups of 26 time-mated CD rats were fed various amounts of Purina 5002 diet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac796b11c73bab88761d6fb70881229
https://doi.org/10.1093/toxsci/kfh249
https://doi.org/10.1093/toxsci/kfh249
Autor:
Amanda K. Andrus, Reza J. Rasoulpour, Robert G. Ellis-Hutchings, Edward W. Carney, Carol L. Zablotny, Nicholas Ball
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 49
In rats, 2-amino-2-methylpropanol (AMP) caused an increase in postimplantation loss in an oral reproductive/developmental toxicity screening assay but not in a dermal developmental toxicity assay. Studies were performed to characterize the mode of ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28e0333d4b4111ba9004e9a02e05cf8
https://pubmed.ncbi.nlm.nih.gov/25088246
https://pubmed.ncbi.nlm.nih.gov/25088246
Autor:
Barry L. Yano, Mary Sue Marty, Darrell R. Boverhof, Marie Lawson, James S. Bus, Amanda K. Andrus, Barbara H. Neal, Larry Hammond, Carol L. Zablotny, James C. Lamb, Adam W. Perala, Julie K. Passage, Shakil A. Saghir, Michael R. Woolhiser
Publikováno v:
Toxicological Sciences
2,4-Dichlorophenoxyacetic acid (2,4-D) was assessed for systemic toxicity, reproductive toxicity, developmental neurotoxicity (DNT), developmental immunotoxicity (DIT), and endocrine toxicity. CD rats (27/sex/dose) were exposed to 0, 100, 300, 600 (f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc7cb63d8ad72614a8ba735338c3bb7
https://pubmed.ncbi.nlm.nih.gov/24072463
https://pubmed.ncbi.nlm.nih.gov/24072463
Autor:
Valerie A. Marshall, M.P. Bell, Bethany R. Hannas, Reza J. Rasoulpour, Sabitha Papineni, Lynea Murphy, Carol L. Zablotny
Publikováno v:
Toxicology Letters. 258:S311
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cab08b30025d7e6a0a0247122fc9ca0
https://doi.org/10.1016/j.toxlet.2016.06.2062
https://doi.org/10.1016/j.toxlet.2016.06.2062
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 62(3)
Diiodomethyl-p-tolylsulfone (DIMPTS) was tested in developmental toxicity (DT) and reproductive toxicity studies. In the rat DT study, DIMPTS was administered at 0, 100, 300 or 1000 mg/kg/day. Maternal toxicity as evidenced by reductions in body weig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ab03ec1162eee2db98f6d1abab0c14
https://pubmed.ncbi.nlm.nih.gov/22178771
https://pubmed.ncbi.nlm.nih.gov/22178771
Autor:
Amy J. Clark, Barry L. Yano, Jennifer L. Staley, Kathy A. Brzak, Shakil A. Saghir, Carol L. Zablotny
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 62(3)
Metabolism of diiodomethyl-p-tolylsulfone (DIMPTS) was investigated in rats to determine the role of iodide in its toxicity. Fischer 344 (F-344) (5 or 50mg/kg) or Sprague Dawley (SD) (5mg/kg) rats were gavaged with (14)C-DIMPTS or dermally applied wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57926b234c4ba831692e3faacb20e306
https://pubmed.ncbi.nlm.nih.gov/21986257
https://pubmed.ncbi.nlm.nih.gov/21986257