Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Carol L. Roberts"'
Autor:
Hannah L. Simpson, Carol L. Roberts, Louise M. Thompson, Cameron R. Leiper, Nehana Gittens, Ellie Trotter, Carrie A. Duckworth, Stamatia Papoutsopoulou, Fabio Miyajima, Paul Roberts, Niamh O’Kennedy, Jonathan M. Rhodes, Barry J. Campbell
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Clostridioides difficile infection (CDI) is a leading cause of antibiotic-associated diarrhoea. Adhesion of this Gram-positive pathogen to the intestinal epithelium is a crucial step in CDI, with recurrence and relapse of disease dependent on epithel
Externí odkaz:
https://doaj.org/article/867acb7cde0d44d4a188a5bd42a14a9e
Autor:
Maelle Prorok-Hamon, Julian R. Marchesi, Paul Knight, Barry J. Campbell, Jonathan M. Rhodes, Caroline E. Codling, Fei Song, Melissa K. Friswell, Paul K Flanagan, Carol L. Roberts, Neil Hall, Abdullah Alswied, Craig Winstanley
Publikováno v:
Gut
Objective: Colonic mucosa-associated Escherichia coli are increased in Crohn's disease (CD) and colorectal cancer (CRC). They variously haemagglutinate, invade epithelial cell lines, replicate within macrophages, translocate across M (microfold) cell
Autor:
Jonathan M. Rhodes, Maelle Prorok-Hamon, Craig Winstanley, Carol L. Roberts, Åsa V. Keita, Paul Knight, Niamh O′Kennedy, Bryony N. Parsons, Johan D. Söderholm, Barry J. Campbell
Publikováno v:
The Journal of Nutritional Biochemistry
Dietary fibres may have prebiotic effects mediated by promotion of beneficial bacteria. This study explores the possibility that soluble plant fibre may also improve health by inhibiting epithelial adhesion and translocation by pathogenic bacteria. W
Autor:
Sreedhar Subramanian, Barry J. Campbell, Ben Tam, Craig Winstanley, Carol L. Roberts, John E. Corkill, Jonathan M. Rhodes, Mumtaz Virji, Shirley L Smith, C. Anthony Hart
Publikováno v:
Inflammatory Bowel Diseases
Background: Mucosally adherent E. coli are found in inflammatory bowel disease (IBD) and colon cancer. They promote release of the proinflammatory cytokine interleukin-8 (IL-8). We explored mechanisms for this release and its inhibition by drugs. Met
Autor:
Jonathan M. Rhodes, Anne-Marie Salisbury, Hannah L. Simpson, David O'Brien, Bryony N. Parsons, Jonathan M. Williams, Niamh O'Kennedy, Carol L. Roberts, Barry J. Campbell, Suzie Humphrey, Paul Wigley, Johan D. Söderholm, Alastair J.M. Watson, Åsa V. Keita, Stephen C. Fry
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87658 (2014)
PLoS ONE
Parsons, B N, Wigley, P, Simpson, H L, Williams, J M, Humphrey, S, Salisbury, A-M, Watson, A J M, Fry, S C, O'Brien, D, Roberts, C L, O'Kennedy, N, Keita, A V, Söderholm, J D, Rhodes, J M & Campbell, B J 2014, ' Dietary supplementation with soluble plantain non-starch polysaccharides inhibits intestinal invasion of salmonella typhimurium in the chicken ', PLoS ONE, vol. 9, no. 2, e87658 . https://doi.org/10.1371/journal.pone.0087658
PLoS ONE
Parsons, B N, Wigley, P, Simpson, H L, Williams, J M, Humphrey, S, Salisbury, A-M, Watson, A J M, Fry, S C, O'Brien, D, Roberts, C L, O'Kennedy, N, Keita, A V, Söderholm, J D, Rhodes, J M & Campbell, B J 2014, ' Dietary supplementation with soluble plantain non-starch polysaccharides inhibits intestinal invasion of salmonella typhimurium in the chicken ', PLoS ONE, vol. 9, no. 2, e87658 . https://doi.org/10.1371/journal.pone.0087658
Soluble fibres (non-starch polysaccharides, NSP) from edible plants but particularly plantain banana (Musa spp.), have been shown in vitro and ex vivo to prevent various enteric pathogens from adhering to, or translocating across, the human intestina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0c3275e1ca3503ea7b19131600079a
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-105237
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-105237
Autor:
Carol L. Roberts, Katrina Stewart, Tristan Lefébure, Michael J. Stanhope, Haruo Suzuki, Barry J. Campbell, Ellen Scherl, Paulina D. Pavinski Bitar, Kenneth W. Simpson, Belgin Dogan, Ynte H. Schukken, Balfour R. Sartor, Brendan Chandler, Deepali Herlekar, Yasemin Araz
Publikováno v:
Inflammatory Bowel Diseases
Inflammatory Bowel Diseases, Lippincott, Williams & Wilkins, 2014, 20 (2), pp.1919-1932. ⟨10.1097/MIB.0000000000000183⟩
Inflammatory Bowel Diseases, Lippincott, Williams & Wilkins, 2014, 20 (2), pp.1919-1932. ⟨10.1097/MIB.0000000000000183⟩
Background: Perturbations of the intestinal microbiome, termed dysbiosis, are linked to intestinal inflammation. Isolation of adherent-invasive Escherichia coli (AIEC) from intestines of patients with Crohn’s disease (CD), dogs with granulomatous c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d0d956988537cb4b12257ceb716b3b
https://hal-sde.archives-ouvertes.fr/hal-01332099
https://hal-sde.archives-ouvertes.fr/hal-01332099
Publikováno v:
Journal of Crohn'scolitis. 7(4)
Crohn's disease (CD) incidence has increased over the past fifty years but the explanation is unclear. CD can be brought into remission by liquid enteral feeding, but the mechanism for this response is unknown. We suggest that consumption of emulsifi
Autor:
Steve W. Edwards, Sreedhar Subramanian, Barry J. Campbell, Carol L. Roberts, C. Anthony Hart, Jonathan M. Rhodes, Helen M. Martin
Publikováno v:
Antimicrobial agents and chemotherapy. 52(2)
There is increasing evidence that Escherichia coli organisms are important in Crohn's disease (CD) pathogenesis. In CD tissue they are found within macrophages, and the adherent-invasive CD ileal E. coli isolate LF82 can replicate inside macrophage p
Autor:
Stuart Marshall–Clarke, Jonathan M. Rhodes, A McGoldrick, Carol L. Roberts, Chiedzo Mpofu, Andrew Cross, Steven W. Edwards, C. Anthony Hart, Sreedhar Subramanian, Barry J. Campbell
Publikováno v:
Gastroenterology. 133(5)
Crohn's disease (CD) is mimicked by inherited phagocyte disorders and is associated with circulating antibodies against yeast mannan (anti-Saccharomyces cerevisiae antibody; ASCA). We speculated that mannans might impair phagocyte function.S cerevisi
Publikováno v:
Gut. 61:A85.2-A85
Introduction It has long been thought that dietary fibre promotes intestinal health and we have previously shown that the soluble non-starch polysaccharide (NSP) from plantain bananas ( Musa spp.) can inhibit the epithelial adhesion and microfold (M)