A single clonal lineage of transmissible cancer identified in two marine mussel species in South America and Europe

Autor: Nicolás Merino-Véliz, Florencia Cremonte, Gloria Arriagada, Maryline Houssin, Maurine Hammel, Susan A. Baldwin, Marisa A. Yonemitsu, Annette F. Muttray, Carol L. Reinisch, Stephen P. Goff, Michael J. Metzger, James P. Sherry, Maria Polo-Prieto, Nicolas Bierne, Nuria Natalia Vázquez, Alexis Simon, Rachael M. Giersch, E. A. V. Burioli, Fernando T Avilés

Publikováno v: eLife
eLife, eLife Sciences Publication, 2019, 8, pp.e47788. ⟨10.7554/eLife.47788⟩
Elife (2050-084X) (eLife Sciences Publications, Ltd), 2019-11, Vol. 8, P. e47788 (21p.)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
eLife, 2019, 8, pp.e47788. ⟨10.7554/eLife.47788⟩
eLife, Vol 8 (2019)

Transmissible cancers, in which cancer cells themselves act as an infectious agent, have been identified in Tasmanian devils, dogs, and four bivalves. We investigated a disseminated neoplasia affecting geographically distant populations of two specie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd22d30c51515ad7bd9ebfe2c218cff
https://elifesciences.org/articles/47788

Detecting p53 family proteins in haemocytic leukemia cells ofMytilus edulisfrom Pictou Harbour, Nova Scotia, Canada

Autor: Sylvie D. St-Jean, R.E. Stephens, Simon C. Courtenay, Carol L. Reinisch

Publikováno v: Canadian Journal of Fisheries and Aquatic Sciences. 62:2055-2066

Evaluating patterns of expression of p53-related proteins in cells is a novel approach in defining environ- mentally linked diseases. We have examined the induction of haemocytic leukemia in Mytilus edulis by municipal and industrial contaminants in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::729dada8daa4ba06f06078e3462e8db3
https://doi.org/10.1139/f05-119

A new invertebrate member of the p53 gene family is developmentally expressed and responds to polychlorinated biphenyls

Autor: Carol L. Reinisch, Marjorie E. Steele, Gail S. Begley, Kathryn Jessen-Eller, Charles W Walker, R.E. Stephens, Jill A. Kreiling

Publikováno v: Environmental Health Perspectives

The cell-cycle checkpoint protein p53 both directs terminal differentiation and protects embryos from DNA damage. To study invertebrate p53 during early development, we identified three differentially expressed p53 family members (p53, p97, p120) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf3d1e21b6dd28f0b51b994dd5b87d9
https://doi.org/10.1289/ehp.02110377

Detection of Mutant p53 in Clam Leukemia Cells

Autor: Charles W. Walker, Carol L. Reinisch, Colin M. Barker, Richard J. Calvert

Publikováno v: Experimental Cell Research. 232:240-245

Leukemia in the soft-shell clam, Mya arenaria, is characterized by tumor cells which are detected initially in the hemolymph. This disease is much more common in clams inhabiting polluted waters, suggesting an environmental component to its pathogene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02d7902d166555aa2878f06becc5a78
https://doi.org/10.1006/excr.1997.3513

A novel adhesion protein expressed by ciliated epithelium, hemocytes, and leukemia cells in soft-shell clams

Autor: Roxanna M. Smolowitz, Carol L. Reinisch

Publikováno v: Developmental & Comparative Immunology. 17:475-481

The ontogeny of circulating hemocytes and tumor cells in mollusks has been approached using monoclonal antibodies to normal cells. A monoclonal antibody, previously shown to identify an adhesion related protein (p130), has been used to define the rea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a33818a0e3ec18a270afde40e7afcd
https://doi.org/10.1016/s0145-305x(05)80003-5