Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Carol L. O'Neal"'
Publikováno v:
Forensic Science International. 109:189-201
Validation procedures are described for 12 chemical spot tests including cobalt thiocyanate, Dille–Koppanyi, Duquenois–Levine, Mandelin, Marquis, nitric acid, para -dimethylaminobenzaldehyde, ferric chloride, Froehde, Mecke, Zwikker and Simon's (
Publikováno v:
Journal of Analytical Toxicology. 23:452-459
A clinical study was designed to determine if there was a predictable relationship between saliva and plasma codeine concentrations. Drug-free volunteers (n = 17) were administered a 30-mg dose of liquid codeine phosphate. Plasma and saliva specimens
Autor:
Carol L. O'Neal, Alphonse Poklis
Publikováno v:
Journal of Analytical Toxicology. 22:487-492
I A diagnostic system to predict the presence of 6-acetylmorphine (6AM) in opiate-positive urines was recently proposed. A twofold criterion based on the total morphine concentration and the total codeine to total morphine concentration ratio was ide
Autor:
Carol L. O'Neal, Alphonse Poklis
Publikováno v:
Forensic Science International. 79:69-81
The major metabolite of hydroxylated benzodiazepines is the β-glucuronide metabolite, thus a hydrolysis step is included in benzodiazepine analyses in urine. We evaluated the new Alltech ( R , S ) oxazepam and lorazepam β-glucuronide primary refere
Publikováno v:
Forensic Science International. 86:141-143
Autor:
Gerald G. Krueger, Atsuhiro Mizuno, Carol L. O'Neal, Diana G. Wilkins, Matthew H. Slawson, Douglas E. Rollins, Marc Augsburger, Chad R. Borges
Publikováno v:
Journal of analytical toxicology, vol. 27, no. 8, pp. 545-551
The influence of melanin on the binding of xenobiotics in hair will impact the interpretation of drug concentrations determined by hair testing. The purpose of this study was to determine if codeine, as a model compound of abused drugs, would be inco
Autor:
Carol L, O'Neal, Alphonse, Poklis
Publikováno v:
Journal of forensic sciences. 47(2)
Publikováno v:
Drug and alcohol dependence. 65(1)
Acetylcodeine is one of the major impurities present in illicitly manufactured heroin (diacetylmorphine). Data on its pharmacology and toxicology are limited and its ability to alter the toxic effects of diacetylmorphine is not known. The first objec
Autor:
Alphonse Poklis, Carol L. O'Neal
Publikováno v:
Forensic science international. 95(1)
Acetylcodeine (AC), an impurity of illicit heroin synthesis, was investigated as a urinary biomarker for detection of illicit heroin use. One hundred criminal justice urine specimens that had been confirmed positive by GC/MS for morphine at concentra
Publikováno v:
Journal of analytical toxicology. 21(6)
Recent innovations in mass spectrometry (MS) have led to the development of instruments with increased capabilities, smaller footprints, and relatively low cost. The traditional MS in most toxicology laboratories is a quadrupole system equipped with