Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Carol L. Nilsson"'
Autor:
Norelle C. Wildburger, Cheryl F. Lichti, Richard D. LeDuc, Mary Schmidt, Roger A. Kroes, Joseph R. Moskal, Carol L. Nilsson
Publikováno v:
EuPA Open Proteomics, Vol 8, Iss C, Pp 94-103 (2015)
Bone marrow-derived human mesenchymal stem cells (BM-hMSCs) show promise as cell-based delivery vehicles for anti-glioma therapeutics, due to innate tropism for gliomas. However, in clinically relevant human-in-mouse glioma stem cell xenograft models
Externí odkaz:
https://doaj.org/article/1246121ec9ef4c82972fd2a1cebfd6f9
Autor:
Cheryl F. Lichti, Norelle C. Wildburger, Alexander S. Shavkunov, Ekaterina Mostovenko, Huiling Liu, Erik P. Sulman, Carol L. Nilsson
Publikováno v:
EuPA Open Proteomics, Vol 8, Iss C, Pp 85-93 (2015)
Glioma stem-like cells (GSCs) are hypothesized to provide a repository of cells in tumors that can self-replicate and are radio- and chemo-resistant. GSC lines, representing several glioma subtypes, have been isolated and characterized at the transcr
Externí odkaz:
https://doaj.org/article/e4ebd1550ff149ed96ff743523da31fa
Autor:
Jennifer S. Brodbelt, Carol L. Nilsson, James D. Sanders, M. Rachel Mehaffey, Dustin D. Holden
Publikováno v:
Analytical Chemistry. 90:9904-9911
Unraveling disease mechanisms requires a comprehensive understanding of how the interplay between higher-order structure and protein-ligand interactions impacts the function of a given protein. Recent advances in native mass spectrometry (MS) involvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee749782aec86280fbaed6f309cadaa
https://doi.org/10.1021/acs.analchem.8b02099
https://doi.org/10.1021/acs.analchem.8b02099
Publikováno v:
Journal of the American Society for Mass Spectrometry. 29:1065-1074
The structural study of glycans and glycoconjugates is essential to assign their roles in homeostasis, health, and disease. Once dominated by nuclear magnetic resonance spectroscopy, mass spectrometric methods have become the preferred toolbox for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1f826bb0c4121157249aee21bb0ba43
https://doi.org/10.1007/s13361-018-1912-3
https://doi.org/10.1007/s13361-018-1912-3
Autor:
Georgina Armstrong, Carol L. Nilsson, E. Susan Amirian, Yanhong Liu, Spiridon Tsavachidis, Melissa L. Bondy, Ekaterina Mostovenko
Publikováno v:
ACS Chemical Neuroscience. 9:80-84
Primary brain tumors are predominantly malignant gliomas. Grade IV astrocytomas (glioblastomas, GBM) are among the most deadly of all tumors; most patients will succumb to their disease within 2 years of diagnosis despite standard of care. The grim o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417e6ac40efd5ae1029db98748a9a5d4
https://doi.org/10.1021/acschemneuro.7b00165
https://doi.org/10.1021/acschemneuro.7b00165
Publikováno v:
Journal of the American Society for Mass Spectrometry
Structural technologies are an essential component in the design of precision therapeutics. Precision medicine entails the development of therapeutics directed toward a designated target protein, with the goal to deliver the right drug to the right p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133f2a3cae82046aa9582410be76f150
https://doi.org/10.1007/s13361-017-1705-0
https://doi.org/10.1007/s13361-017-1705-0
Autor:
Carol L. Nilsson, Roger A. Kroes
Publikováno v:
Current Neuropharmacology
Background: Depression affects over 120 million individuals of all ages and is the leading cause of disability worldwide. The lack of objective diagnostic criteria, together with the heterogeneity of the depressive disorder itself, makes it challengi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328268b9ee860b4bd12b9a891420245b
https://doi.org/10.2174/1570159x14666160309114740
https://doi.org/10.2174/1570159x14666160309114740
Publikováno v:
ACS Chemical Neuroscience. 9:8-10
Chemotherapeutics are vital for treating brain tumors such as glioblastoma, an aggressive and prolific cancer predominantly treated with DNA alkylating agents. The efficacy of antiglioblastoma drugs, such as temozolomide, is limited by their rapid cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a971512a442fe03f1670ca830e2b78f7
https://doi.org/10.1021/acschemneuro.7b00168
https://doi.org/10.1021/acschemneuro.7b00168
Autor:
Huiling Liu, Erik P. Sulman, Norelle C. Wildburger, Ekaterina Mostovenko, Alexander S. Shavkunov, Carol L. Nilsson, Cheryl F. Lichti
Publikováno v:
EuPA Open Proteomics, Vol 8, Iss C, Pp 85-93 (2015)
Glioma stem-like cells (GSCs) are hypothesized to provide a repository of cells in tumors that can self-replicate and are radio- and chemo-resistant. GSC lines, representing several glioma subtypes, have been isolated and characterized at the transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc844b3a2bf4657932bd280d2093fba2
https://doi.org/10.1016/j.euprot.2015.06.008
https://doi.org/10.1016/j.euprot.2015.06.008
Autor:
Richard D. LeDuc, Cheryl F. Lichti, Joseph R. Moskal, Mary F. Schmidt, Roger A. Kroes, Carol L. Nilsson, Norelle C. Wildburger
Publikováno v:
EuPA Open Proteomics, Vol 8, Iss C, Pp 94-103 (2015)
Bone marrow-derived human mesenchymal stem cells (BM-hMSCs) show promise as cell-based delivery vehicles for anti-glioma therapeutics, due to innate tropism for gliomas. However, in clinically relevant human-in-mouse glioma stem cell xenograft models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c5fd45ed8f71cb10edf44088c53f30
https://doi.org/10.1016/j.euprot.2015.06.006
https://doi.org/10.1016/j.euprot.2015.06.006