Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Carol J. Swanson"'
Autor:
Barbara J. Olack, Michael Alexander, Carol J. Swanson, Julie Kilburn, Nicole Corrales, Antonio Flores, Jennifer Heng, Jayagowri Arulmoli, Keiko Omori, Peter J. Chlebeck, Laura Zitur, Mayra Salgado, Jonathan R.T. Lakey, Joyce C. Niland
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Access to functional high-quality pancreatic human islets is critical to advance diabetes research. The Integrated Islet Distribution Program (IIDP), a major source for human islet distribution for over 15 years, conducted a study to evaluate the mos
Externí odkaz:
https://doaj.org/article/3a982b8a25d949beb6d2b94c00388c94
Autor:
Nicole Corrales, Joyce C. Niland, Barbara Olack, Peter J. Chlebeck, Michael Alexander, Jonathan R. T. Lakey, Antonio Flores, Mayra Salgado, Jennifer Heng, Carol J Swanson, Julie Kilburn, Jayagowri Arulmoli, Keiko Omori, Laura J. Zitur
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Access to functional high-quality pancreatic human islets is critical to advance diabetes research. The Integrated Islet Distribution Program (IIDP), a major source for human islet distribution for over 15 years, conducted a study to evaluate the mos
Autor:
Zahid Kaleem, Jeffrey A. Lowell, Barbara Olack, Andrés Jaramillo, N. Benshoff, Carol J. Swanson, T. Mohanakumar
Publikováno v:
Xenotransplantation. 9:393-401
We have previously demonstrated that human T cells responding to porcine islets are primarily CD4+ and recognized porcine major histocompatibility complex class I molecules through the indirect pathway of antigen presentation. To determine whether th
Publikováno v:
Human Immunology. 62:739-749
Recent progress in human islet transplantation demonstrates the feasibility of using purified human islets for treatment of type 1 diabetes mellitus; however, a shortage of human pancreata remains a major obstacle. This report describes methods to is
Autor:
T. Mohanakumar, Craig Smith, Wei Liu, Carol J. Swanson, Zahid Kaleem, Yizheng Tu, Andr s Jaramillo
Publikováno v:
Transplantation. 71:1640-1648
To further define the role of indirect allorecognition, cardiac allografts from HLA-A2-transgenic (HLA-A2+) C57BL/6 mice were heterotopically transplanted into normal C57BL/6, CD4 T cell-knockout (KO) C57BL/6 mice, CD8 T cell-KO C57BL/6 mice, fully M
Publikováno v:
Human Immunology. 60:1303-1309
To determine the effects of procedural modifications, 23 human islet isolations were analyzed. Isolations were divided into two groups based on the enzyme used. The influence of Liberase, with an improved method of mechanical disassociation of pancre
Autor:
Maha F Ansara, Paul E. Lacy, Orion D. Hegre, David W. Scharp, Paul Latta, Frank T. Gentile, Barbara Olack, Carol J. Swanson, Karen Flavin, Doherty Edward J
Publikováno v:
Diabetes. 43:1167-1170
Human islets were macroencapsulated in permselective hollow fiber membrane devices and successfully allotransplanted subcutaneously with > 90% viability after 2 weeks in situ. Recipients were patients with type I or type II diabetes and normal contro
Autor:
Paul E. Lacy, Rosa Giannarelli, R. Navalesi, Edward H. Finke, Ronald L. Gingerich, Carol J. Swanson, M. Mclear, Piero Marchetti, David W. Scharp, Barbara Olack
Publikováno v:
Scopus-Elsevier
Insulin secretion from the pancreas is pulsatile. The precise site and function of the pacemaker that regulates insulin periodicity in humans have not been determined. We isolated human pancreatic islets from five cadaver organ donors by collagenase
Autor:
Paul E. Lacy, Kim Pfiffner, Piero Marchetti, Edward H. Finke, A. Gerasimidi-Vazeou, Carol J. Swanson, Barbara Olack, M. Mclear, David W. Scharp
Publikováno v:
Scopus-Elsevier
Highly purified islets of Langerhans were prepared in the present study from adult pigs by collagenase digestion and density gradient purification. After overnight culture, the tissue was equilibrated with DMSO at 25 degrees C, supercooled to -7.5 de
Autor:
Edward H. Finke, P. E. Lacy, R. Navalesi, David W. Scharp, Carol J. Swanson, Rosa Giannarelli, Barbara Olack, Piero Marchetti, D Gerasimidi-Vazeou
Publikováno v:
Transplantation. 61:1100-1102
Purified porcine islets were prepared by collagenase digestion and density gradient purification, and transplanted under the kidney capsule of C57B/B6 mice with streptozotocin-induced diabetes which were receiving varying temporary immunosuppressive