Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Carol J Soroka"'
Autor:
Shuhua Xu, Carol J Soroka, An-Qiang Sun, Donald S Backos, Albert Mennone, Frederick J Suchy, James L Boyer
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158269 (2016)
The heteromeric membrane protein Organic Solute Transporter alpha/beta is the major bile acid efflux transporter in the intestine. Physical association of its alpha and beta subunits is essential for their polarized basolateral membrane localization
Externí odkaz:
https://doaj.org/article/d50aac9e0e4849489dda2f9e20503fbb
Autor:
Yu Du, Kapish Gupta, Orith Waisbourd-Zinman, Adi Har-Zahav, Carol J. Soroka, James L. Boyer, Jessica Llewellyn, Chengyang Liu, Ali Naji, William J. Polacheck, Rebecca G. Wells
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease in which the bile ducts of the liver become inflamed and scarred. Scarred bile ducts eventually narrow and obstruct and can cause additional liver pathology including liver f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7eef1236aff159191bd79bb02fe9291
https://doi.org/10.1101/2023.03.02.530888
https://doi.org/10.1101/2023.03.02.530888
Publikováno v:
Seminars in Liver Disease. 41:206-212
Translational studies in human cholestatic diseases have for years been hindered by various challenges, including the rarity of the disorders, the difficulty in obtaining biliary tissue from across the spectrum of the disease stage, and the difficult
Autor:
Nihan Erden, Carol J. Soroka, James L. Boyer, Youssef Khalil, Iqra Mushtaq, Silvia Vilarinho, Emily Gao, Dhanpat Jain, Pramod K. Mistry, Richard P. Lifton, Huma Arshad Cheema, Peter E. Clayton, Carol Nelson-Williams, Nadia K. Waheed
Publikováno v:
Hepatology
Autor:
Carol J. Soroka, James L. Boyer
Publikováno v:
Journal of hepatology. 75(1)
Summary Bile formation is a fundamental physiological process that is vital to the survival of all vertebrates. However, little was known about the mechanisms of this secretion until after World War II. Initial studies involved classic physiologic st
Publikováno v:
J Hepatol
Background & Aims The nuclear factor of activated T-cells (NFAT) plays an important role in immune responses by regulating the expression of inflammatory genes. However, it is not known whether NFAT plays any role in the bile acid (BA)-induced hepati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a81ee6de68013ebed81f510f4304b9b
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1981
Cholangiopathies, including primary sclerosing cholangitis, are a group of heterogeneous diseases characterized by inflammation and fibrosis of the intrahepatic and extrahepatic bile duct epithelium. Studies, especially of primary sclerosing cholangi
Publikováno v:
Methods in Molecular Biology ISBN: 9781493994199
Cholangiopathies, including primary sclerosing cholangitis, are a group of heterogeneous diseases characterized by inflammation and fibrosis of the intrahepatic and extrahepatic bile duct epithelium. Studies, especially of primary sclerosing cholangi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f74b89ce0664442a79d8ac8b223d48d
https://doi.org/10.1007/978-1-4939-9420-5_24
https://doi.org/10.1007/978-1-4939-9420-5_24
Publikováno v:
Journal of Hepatology. 73:S41
Autor:
Leina Alrabadi, David N. Assis, Carol J. Soroka, Scott C. Roberts, Laura Cusack, James L. Boyer, Ariel Jaffe
Publikováno v:
Hepatology (Baltimore, Md.)References. 70(3)
Primary sclerosing cholangitis (PSC) is a heterogeneous and progressive fibroinflammatory cholangiopathy with no known etiology or effective treatment. Studies of PSC are limited due to difficulty in accessing the cholangiocyte, the small percentage