Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Carol J Raport"'
Autor:
Michelle L Scalley-Kim, Bruce W Hess, Ryan L Kelly, Anne-Rachel F Krostag, Kurt H Lustig, John S Marken, Pamela J Ovendale, Aaron R Posey, Pamela J Smolak, Janelle D L Taylor, C L Wood, David L Bienvenue, Peter Probst, Ruth A Salmon, Daniel S Allison, Teresa M Foy, Carol J Raport
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43332 (2012)
Chemokines play a key role in leukocyte recruitment during inflammation and are implicated in the pathogenesis of a number of autoimmune diseases. As such, inhibiting chemokine signaling has been of keen interest for the development of therapeutic ag
Externí odkaz:
https://doaj.org/article/dc762b06602041d28f80fcd50dabb157
Autor:
Benjamin H. Dutzar, Ethan W. Ojala, Charlie Karasek, Carol J. Raport, Dan Scott Allison, Jens J. Billgren, Leon F. Garcia-Martinez, Brian Baker, Michelle Scalley-Kim, Erica Stewart, Brian Kovacevich, John A. Latham, Katie Anderson
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 374:93-103
ALD403 is a genetically engineered, humanized immunoglobulin G1 monoclonal antibody that inhibits the action of human calcitonin gene-related peptide (CGRP). Clinical trial data indicate that ALD403 is effective as a preventive therapy for migraine a
Autor:
Christi L. Wood, David Chantry, Patrick W. Gray, Carol J. Raport, Sergio Romagnani, Angela Epp, Paola Romagnani
Publikováno v:
Blood. 94:1890-1898
Macrophage-derived chemokine (MDC) is a recently identified CC chemokine that is a potent chemoattractant for dendritic cells, natural killer (NK) cells, and the Th2 subset of peripheral blood T cells. In normal tissues, MDC mRNA is expressed princip
Autor:
David Chantry, Paola Romagnani, Carol J. Raport, Christi L. Wood, Angela Epp, Sergio Romagnani, Patrick W. Gray
Publikováno v:
Blood. 94:1890-1898
Macrophage-derived chemokine (MDC) is a recently identified CC chemokine that is a potent chemoattractant for dendritic cells, natural killer (NK) cells, and the Th2 subset of peripheral blood T cells. In normal tissues, MDC mRNA is expressed princip
Autor:
Vicki L. Schweickart, Heather Brammer, Ronald Godiska, Christi L. Wood, Anthony J. Demaggio, David Chantry, Carol J. Raport, Kim Walton, Johnny T. Stine, Aaron Smith, Larry W. Tjoelker, Angela Epp, Patrick W. Gray
Publikováno v:
Journal of Leukocyte Biology. 64:49-54
High throughput partial sequencing of randomly selected cDNA clones has proven to be a powerful tool for examining the relative abundance of mRNAs and for the identification of novel gene products. Because of the important role played by macrophages
Autor:
Hirotsugu Ueda, Michael Grimm, Carol J. Raport, Wanghua Gong, Jim A. Turpin, O. M. Zack Howard, Patrick W. Gray, Ji Ming Wang, Joost J. Oppenheim
Publikováno v:
Journal of Biological Chemistry. 273:4289-4292
Human immunodeficiency virus, type I (HIV-1) cell-type tropism is dictated by chemokine receptor usage: T-cell line tropic viruses use CXCR4, whereas monocyte tropic viruses primarily use CCR5 as fusion coreceptors. CC chemokines macrophage inflammat
Autor:
Christi L. Wood, Osamu Yoshie, David Chantry, Miyuki Nishimura, Patrick W. Gray, Toshio Imai, Carol J. Raport, Ronald Godiska
Publikováno v:
Journal of Biological Chemistry. 273:1764-1768
Macrophage-derived chemokine (MDC) is a recently identified member of the CC chemokine family. MDC is not closely related to other chemokines, sharing most similarity with thymus- and activation-regulated chemokine (TARC), which contains 37% identica
Autor:
Carol J. Raport, Patrick W. Gray, Paola Allavena, Dina Leviten, Silvano Sozzani, Ronald Godiska, Alberto Mantovani, David Chantry
Publikováno v:
The Journal of Experimental Medicine
A cDNA encoding a novel human chemokine was isolated by random sequencing of cDNA clones from human monocyte-derived macrophages. This protein has been termed macrophagederived chemokine (MDC) because it appears to be synthesized specifically by cell
Autor:
Thomas B. Shows, Vicki L. Schweickart, David Chantry, Ronald Godiska, Carol J. Raport, Patrick W. Gray, Roger L. Eddy
Publikováno v:
Journal of Leukocyte Biology. 59:18-23
Chemokines are relatively small peptides with potent chemoattractant and activation activities for leukocytes. Several chemokine receptors have been cloned and characterized and all are members of the G protein-coupled receptor superfamily. Using deg
Autor:
Vicki L. Schweickart, Carol J. Raport, M.G. Byers, Ronald Godiska, Thomas B. Shows, Patrick W. Gray, Roger L. Eddy
Publikováno v:
Genomics. 23:643-650
A lymphoid-specific member of the G-protein-coupled receptor family has been identified by PCR with degenerate oligonucleotides. We have determined that this receptor, also reported as the Epstein-Barr-induced cDNA EBI1, is expressed in normal lympho