Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Carol E. Cass"'
Autor:
Mahalakshmi Kumaran, Preethi Krishnan, Carol E. Cass, Roland Hubaux, Wan Lam, Yutaka Yasui, Sambasivarao Damaraju
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Copy Number Variants (CNVs) are a class of structural variations of DNA. Germline CNVs are known to confer disease susceptibility, but their role in breast cancer warrants further investigations. We hypothesized that breast cancer associated
Externí odkaz:
https://doaj.org/article/0a8aab14164b4afaaa9d425c68417891
Autor:
Robert J. Reklow, Tucaaue S. Alvares, Yong Zhang, Ana P. Miranda Tapia, Vivian Biancardi, Alexis K. Katzell, Sara M. Frangos, Megan A. Hansen, Alexander W. Toohey, Carol E. Cass, James D. Young, Silvia Pagliardini, Detlev Boison, Gregory D. Funk
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Exploration of purinergic signaling in brainstem homeostatic control processes is challenging the traditional view that the biphasic hypoxic ventilatory response, which comprises a rapid initial increase in breathing followed by a slower secondary de
Externí odkaz:
https://doaj.org/article/e433dca14c03434abf16ad50ac268923
Autor:
Florian C. Maier, Anna Schweifer, Vijaya L. Damaraju, Carol E. Cass, Gregory D. Bowden, Walter Ehrlichmann, Manfred Kneilling, Bernd J. Pichler, Friedrich Hammerschmidt, Gerald Reischl
Publikováno v:
Pharmaceuticals, Vol 12, Iss 1, p 31 (2019)
The benefits of PET imaging of tumor hypoxia in patient management has been demonstrated in many examples and with various tracers over the last years. Although, the optimal hypoxia imaging agent has yet to be found, 2-nitroimidazole (azomycin) sugar
Externí odkaz:
https://doaj.org/article/6eea80e75643418a81865cbc411b6abd
Autor:
Philippe Gros, Carol E. Cass, Morris J. Robins, Yunshan Peng, Delores Mowles, Normand Groulx, Vijaya L. Damaraju, Jie Cai
Supplementary Figure 1 from Two Distinct Molecular Mechanisms Underlying Cytarabine Resistance in Human Leukemic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35420a2c1a15ea102e9d64786a81328a
https://doi.org/10.1158/0008-5472.22375320
https://doi.org/10.1158/0008-5472.22375320
Data from Two Distinct Molecular Mechanisms Underlying Cytarabine Resistance in Human Leukemic Cells
Autor:
Philippe Gros, Carol E. Cass, Morris J. Robins, Yunshan Peng, Delores Mowles, Normand Groulx, Vijaya L. Damaraju, Jie Cai
To understand the mechanism of cellular resistance to the nucleoside analogue cytarabine (1-β-d-arabinofuranosylcytosine, AraC), two resistant derivatives of the human leukemic line CCRF-CEM were obtained by stepwise selection in different concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c75ff89816a4cf3a98cee8ce68c5c6
https://doi.org/10.1158/0008-5472.c.6497769
https://doi.org/10.1158/0008-5472.c.6497769
Autor:
Philippe Gros, Carol E. Cass, Morris J. Robins, Yunshan Peng, Delores Mowles, Normand Groulx, Vijaya L. Damaraju, Jie Cai
Supplementary Table 1 from Two Distinct Molecular Mechanisms Underlying Cytarabine Resistance in Human Leukemic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c237039b567faa26bf2b2ad873fbc7
https://doi.org/10.1158/0008-5472.22375317
https://doi.org/10.1158/0008-5472.22375317
Autor:
Carol E. Cass, Sunita Ghosh, Sambasivarao Damaraju, Mahalakshmi Kumaran, John R. Mackey, Wei Zheng, Yutaka Yasui, Anil Abraham Joy
Publikováno v:
International Journal of Cancer
We previously identified a novel breast cancer susceptibility variant on chromosome 4q31.22 locus (rs1429142) conferring risk among women of European ancestry. Here, we report replication of findings, validation of the variant in diverse populations
Publikováno v:
Biochemical Journal. 475:3293-3309
Human equilibrative nucleoside transporter 1 (hENT1), the first identified member of the ENT family of integral membrane proteins, is the primary mechanism for cellular uptake of physiologic nucleosides and many antineoplastic and antiviral nucleosid
Publikováno v:
Biochemical Pharmacology. 155:162-171
Tyrosine kinase inhibitors (TKIs) have advanced cancer treatment and prognosis but have also resulted in adverse effects such as fatigue, diarrhea, hypothyroidism, and other toxicities. We investigated TKI effects on skeletal muscle as a possible exp
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1862(7)
Humans possess three members of the cation-coupled concentrative nucleoside transporter CNT (SLC 28) family, hCNT1-3: hCNT1 is selective for pyrimidine nucleosides but also transports adenosine, hCNT2 transports purine nucleosides and uridine, and hC