Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carol E. Bansbach"'
Autor:
Jun Qin, Sung Yun Jung, Clinton Carroll, Gloria G. Glick, David Cortez, Carol E. Bansbach, Frank B. Couch, Robert Driscoll, Karlene A. Cimprich, Rémy Bétous, Jessica W. Luzwick
Publikováno v:
Genes & Development. 27:1610-1623
The DNA damage response kinase ataxia telangiectasia and Rad3-related (ATR) coordinates much of the cellular response to replication stress. The exact mechanisms by which ATR regulates DNA synthesis in conditions of replication stress are largely unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab30932f79e0c06b879b1e221a067b8e
https://doi.org/10.1101/gad.214080.113
https://doi.org/10.1101/gad.214080.113
Autor:
David B. Friedman, Runxiang Zhao, David Cortez, Gloria G. Glick, Carol E. Bansbach, Edward A. Nam
Publikováno v:
Journal of Biological Chemistry. 286:28707-28714
The DNA damage response kinases ataxia telangiectasia-mutated (ATM), DNA-dependent protein kinase (DNA-PK), and ataxia telangiectasia-mutated and Rad3-related (ATR) signal through multiple pathways to promote genome maintenance. These related kinases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebeee33e321bf24d30332717b803aa5
https://doi.org/10.1074/jbc.m111.248914
https://doi.org/10.1074/jbc.m111.248914
Autor:
David Cortez, Carol E. Bansbach
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 46:327-341
Genome maintenance activities including DNA repair, cell division cycle control, and checkpoint signaling pathways preserve genome integrity and prevent disease. Defects in these pathways cause birth defects, neurodegeneration, premature aging, and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78311a62cbf1abd5ac8d860b1d43a51e
https://doi.org/10.3109/10409238.2011.588938
https://doi.org/10.3109/10409238.2011.588938
Publikováno v:
Nucleus. 1:245-248
The SNF2 family of ATPases acts in the context of chromatin to regulate transcription, replication, repair and recombination. Defects in SNF2 genes cause many human diseases. For example, mutations in SMARCAL1 (also named HARP) cause Schimke immuno-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c4a537e76bd6aca0c77daabd8251c3
https://doi.org/10.4161/nucl.11739
https://doi.org/10.4161/nucl.11739
Publikováno v:
Nucleic Acids Research
SMARCAL1 promotes the repair and restart of damaged replication forks. Either overexpression or silencing SMARCAL1 causes the accumulation of replication-associated DNA damage. SMARCAL1 is heavily phosphorylated. Here we identify multiple phosphoryla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f9cd310dd7aca9be1c97ae7d1a9934
https://pubmed.ncbi.nlm.nih.gov/24150942
https://pubmed.ncbi.nlm.nih.gov/24150942
Autor:
Bianca M. Sirbu, Aaron C. Mason, Carol E. Bansbach, Robert P. Rambo, Rémy Bétous, David Cortez, Akosua Badu-Nkansah, Brandt F. Eichman
SMARCAL1 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A-like1) maintains genome integrity during DNA replication. Here we investigated its mechanism of action. We found that SMARCAL1 travels with elongating r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc9ba0209ecf6833923fd8d57a3e4ed
https://europepmc.org/articles/PMC3273839/
https://europepmc.org/articles/PMC3273839/
Autor:
Fei Ye, Bianca M. Sirbu, David Cortez, Gloria G. Glick, Carol E. Bansbach, Yu Shyr, Laura C. Titus, Runxiang Zhao, Courtney A. Lovejoy, Xin Xu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(46)
The DNA damage response (DDR) has a critical role in maintaining genome integrity and serves as a barrier to tumorigenesis by promoting cell-cycle arrest, DNA repair, and apoptosis. The DDR is activated not only by genotoxic agents that induce DNA da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c1a7ec7adc82a90c807fd61390c4d7
https://pubmed.ncbi.nlm.nih.gov/19889979
https://pubmed.ncbi.nlm.nih.gov/19889979
Publikováno v:
Genesdevelopment. 23(20)
Mutations in SMARCAL1 (HARP) cause Schimke immunoosseous dysplasia (SIOD). The mechanistic basis for this disease is unknown. Using functional genomic screens, we identified SMARCAL1 as a genome maintenance protein. Silencing and overexpression of SM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79f49b68893e05f466591f1c7502cf6
https://pubmed.ncbi.nlm.nih.gov/19833762
https://pubmed.ncbi.nlm.nih.gov/19833762