Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Carol Dahlberg"'
Autor:
Andrew T Miller, Carol Dahlberg, Mark L Sandberg, Ben G Wen, Daniel R Beisner, John A H Hoerter, Albert Parker, Christian Schmedt, Monique Stinson, Jacqueline Avis, Cynthia Cienfuegos, Mark McPate, Pamela Tranter, Martin Gosling, Paul J Groot-Kormelink, Janet Dawson, Shifeng Pan, Shin-Shay Tian, H Martin Seidel, Michael P Cooke
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131071 (2015)
Emerging approaches to treat immune disorders target positive regulatory kinases downstream of antigen receptors with small molecule inhibitors. Here we provide evidence for an alternative approach in which inhibition of the negative regulatory inosi
Externí odkaz:
https://doaj.org/article/60911ac9821349a2a5779985bf95458d
Autor:
Andrew Kemal Kirchmeier, Corey Cutler, Jerome Ritz, Ryan Flynn, Andrew T. Miller, Jonathan S. Serody, Ivan Maillard, John Koreth, Carol Dahlberg, Michael Loschi, Bruce R. Blazar, David B. Miklos, Angela Panoskaltsis-Mortari, Leo Luznik, Patricia A. Taylor, Kelli P. A. MacDonald, Robert J. Soiffer, Michael Zaiken, Govindarajan Thangavelu, William J. Murphy, David H. Munn, Joseph H. Antin, Jing Du, Geoffrey R. Hill, Katelyn Paz
Publikováno v:
Blood
T-cell activation releases inositol 1,4,5-trisphosphate (IP(3)), inducing cytoplasmic calcium (Ca(2+)) influx. In turn, inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) phosphorylates IP(3) to negatively regulate and thereby tightly control Ca(2+) flu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e22c592b36ad499f7f63b29e9d1f51a
https://pubmed.ncbi.nlm.nih.gov/31697815
https://pubmed.ncbi.nlm.nih.gov/31697815
Autor:
Bruno Martoglio, Michael Young, Sherry Niessen, Petra Langerak, Michael P. Cooke, Daniel R. Beisner, Carol Dahlberg, S. Sutton, Benjamin F. Cravatt, Albert E. Parker, Ursula Bodendorf, Tim Wiltshire, Whitney Barnes, Francella Otero, Laurent Poirot
Publikováno v:
The Journal of Experimental Medicine
The protease Sppl2a cleaves the N-terminal fragment of invariant chain (CD74) and is required for efficient B cell development and function.
B cell development requires tight regulation to allow for the generation of a diverse repertoire while p
B cell development requires tight regulation to allow for the generation of a diverse repertoire while p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db8cd2a3df60b5f6449a15af6a4194a
http://europepmc.org/articles/PMC3549714
http://europepmc.org/articles/PMC3549714
Autor:
Jennifer E. Wu, Zbigniew Mikulski, Shane Crotty, Fortuna Arumemi, Michela Locci, Carol Dahlberg, Andrew T. Miller
Publikováno v:
Nature immunology
SUMMARY Follicular helper T (TFH) cells are CD4+ T cells specialized in helping B cells and are associated both with protective antibody responses and autoimmune diseases. The promise of targeting TFH cells therapeutically has been limited by fragmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c084bba766ba978a1eb49102e007a4
https://pubmed.ncbi.nlm.nih.gov/27376469
https://pubmed.ncbi.nlm.nih.gov/27376469
Autor:
Annegret Van der Aa, Claire Crimi, Scott D. Power, Sidharta Murthy, Alessandro Sette, Lydie Meheus, Jonathan Krakover, Carol Dahlberg, Scott Southwood, Erik Depla, Koen Allosery, Veronique De Brabandere, Manley Huang, Brian D. Livingston, Lilia Maria Babe, Denise M. McKinney, Mark Newman, Ramilla Philip
Publikováno v:
Journal of Virology. 82:435-450
Chronic hepatitis B virus (HBV) infection, which occurs in 1 to 5% of adult infections and up to 30% of pediatric infections, is characterized by high levels of viral replication averaging a daily production of about 1011 viral particles, hepatic inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9152141d873834411fd3884acf1ca27
https://doi.org/10.1128/jvi.01505-07
https://doi.org/10.1128/jvi.01505-07
Autor:
Jennifer E. Wu, Zbigniew Mikulski, Fortuna Arumemi, Andrew T. Miller, Shane Crotty, Carol Dahlberg, Michela Locci
Publikováno v:
Nature immunology. 17(8)
Follicular helper T cells (TFH cells) are CD4(+) T cells specialized in helping B cells and are associated both with protective antibody responses and autoimmune diseases. The promise of targeting TFH cells therapeutically has been limited by fragmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2f873bda560f53f99ea38c5e980ef2
https://pubmed.ncbi.nlm.nih.gov/27648551
https://pubmed.ncbi.nlm.nih.gov/27648551
Autor:
Jing Du, Katelyn Paz, Ryan Flynn, Patricia Taylor, Andrew Miller, Carol Dahlberg, Bruce Blazar
Publikováno v:
The Journal of Immunology. 198:140.1-140.1
Chronic graft versus host disease (cGVHD) is a common and life-threatening complication of allogeneic hematopoietic stem cell transplantation. cGVHD is mediated by donor T cells recognizing and attacking host tissues followed by activation of effecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3db27aa5a03935b473d2e221fdad0925
https://doi.org/10.4049/jimmunol.198.supp.140.1
https://doi.org/10.4049/jimmunol.198.supp.140.1
Autor:
Ajesh Maewal, Alessandro Sette, Howard M. Grey, Carla Oseroff, Jeff Alexander, John Fikes, Carol Dahlberg, Robert W. Chesnut, Peggy Wentworth, Esteban Celis, Ralph T. Kubo
Publikováno v:
Vaccine. 16:823-833
Various peptide-based approaches to simultaneous induction of multiple cytotoxic T lymphocyte (CTL) responses were evaluated as part of ongoing efforts to develop immunotherapeutic vaccines for use in humans. To this end, HLA (human histocompatibilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298a6223a52ff06b1ed651c6b00036b8
https://doi.org/10.1016/s0264-410x(97)00264-8
https://doi.org/10.1016/s0264-410x(97)00264-8
Autor:
Jacqueline Avis, Janet Dawson, Paul J. Groot-Kormelink, Albert E. Parker, Shifeng Pan, Mark L. Sandberg, Ben G. Wen, Andrew T. Miller, Cynthia Cienfuegos, H. Martin Seidel, Monique Stinson, Daniel R. Beisner, John A. H. Hoerter, Michael P. Cooke, Shin-Shay Tian, Pamela Tranter, Martin Gosling, Christian Schmedt, Mark McPate, Carol Dahlberg
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0131071 (2015)
PLoS ONE, Vol 10, Iss 6, p e0131071 (2015)
Emerging approaches to treat immune disorders target positive regulatory kinases downstream of antigen receptors with small molecule inhibitors. Here we provide evidence for an alternative approach in which inhibition of the negative regulatory inosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fb43fc48275a9ddb9265a7e15801e1
https://doi.org/10.1371/journal.pone.0131071
https://doi.org/10.1371/journal.pone.0131071
Autor:
Robert S. Fujinami, Jörg Ruppert, Ikuo Tsunoda, Robert W. Chesnut, Li Qing Kuang, Scott Southwood, Carol Dahlberg, Glenn Ishioka, Ralph T. Kubo, Alessandro Sette, Carla Oseroff, Thomas Arrhenius
Publikováno v:
Vaccine. 17(7-8)
Using a bipalmitoylated lipopeptide consisting of an ovalbumin helper T-cell epitope covalently linked to an influenza virus cytotoxic T-lymphocyte (CTL) epitope, we addressed possible factors that may be critical for CTL induction. Antigen processin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f4b865da9f1c4a9d96a1e54566dfb2
https://pubmed.ncbi.nlm.nih.gov/10067673
https://pubmed.ncbi.nlm.nih.gov/10067673