Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carol Cao"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
During the past decade, there has been a revolution in cancer therapeutics by the emergence of antibody-based immunotherapies that modulate immune responses against tumors. These therapies have offered treatment options to patients who are no longer
Externí odkaz:
https://doaj.org/article/c90816625c944df2937525f21edba765
Autor:
Anthos Christofides, Xanthi-Leda Katopodi, Carol Cao, Dimitra Karagkouni, Konstantinos Aliazis, Sasitorn Yenyuwadee, Rinku Pal, John Asara, Ioannis Vlachos, Nikolaos Patsoukis, Vassiliki A Boussiotis
Publikováno v:
Blood. 140:1403-1404
Autor:
Anthos Christofides, Laura Strauss, Alan Yeo, Carol Cao, Alain Charest, Vassiliki A. Boussiotis
Publikováno v:
Nature immunology. 23(8)
Long recognized as an evolutionarily ancient cell type involved in tissue homeostasis and immune defense against pathogens, macrophages are being re-discovered as regulators of several diseases, including cancer. Tumor-associated macrophages (TAMs) r
Autor:
Vassiliki Boussiotis, Anthos Christofides, Xanthi-Lida Katopodi, Carol Cao, Halil-Ibrahim Aksoylar, Mohamed Mahmoud, Laura Strauss, Natalia Tijaro-Ovalle, Rinku Pal, Louis Boon, John Asara, Ioannis Vlachos, Nikolaos Patsoukis
PD-1 checkpoint inhibitor induces T cell inactivation by recruiting SHP-2. However, T cell-specific SHP-2-deficient mice do not have improved anti-tumor immunity. We generated mice with conditional targeting of the Ptpn11 gene (encoding for Shp-2) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a5b613bc929f133ebe222726dea471e
https://doi.org/10.21203/rs.3.rs-1198158/v1
https://doi.org/10.21203/rs.3.rs-1198158/v1
Autor:
Anthos Christofides, Xanthi-Lida Katopodi, Carol Cao, Dimitra Karagkouni, Konstantinos Aliazis, Sasitorn Yenyuwadee, Halil-Ibrahim Aksoylar, Rinku Pal, Mohamed A. A. Mahmoud, Laura Strauss, Natalia M. Tijaro-Ovalle, Louis Boon, John Asara, Ioannis S. Vlachos, Nikolaos Patsoukis, Vassiliki A. Boussiotis
Publikováno v:
Nature immunology. 24(1)
The inhibitory receptor PD-1 suppresses T cell activation by recruiting the phosphatase SHP-2. However, mice with a T-cell-specific deletion of SHP-2 do not have improved antitumor immunity. Here we showed that mice with conditional targeting of SHP-
Publikováno v:
Journal of Visualized Experiments.
The respiratory tract is in direct contact with the outside environment and requires a precisely regulated immune system to provide protection while suppressing unwanted reactions to environmental antigens. Lungs host several populations of innate an
Autor:
Eirini Konstantinidou, Halil-Ibrahim Aksoylar, Vassiliki A. Boussiotis, Nikolaos Patsoukis, Rinku Pal, Anthos Christofides, Carol Cao, Rushil Shah, Qi Wang, Natalia M. Tijaro-Ovalle, Chinmay Jani
Publikováno v:
Blood. 138:438-438
Peroxisome proliferator activated receptors (PPARs) are transcription factors that belong to nuclear hormone superfamily, with three distinct types identified: PPARapha (PPARα), PPARgamma (PPARγ), and PPARbeta/delta (PPARβ/δ). PPARs possess a cri
Publikováno v:
The Journal of Immunology. 206:101.04-101.04
Initiation of immune responses requires integrin-mediated adhesion between T cells and APC, linking innate and adaptive immunity. Integrins also regulate leukocyte trafficking and extravagation at sites of inflammation. Among the few molecules implic