Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Carol Anne Ogden"'
Autor:
Sandra Santulli-Marotto, Alexis Gervais, Jamie Fisher, Brandy Strake, Carol Anne Ogden, Chelsea Riveley, Jill Giles-Komar
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145078 (2015)
Defective clearance of apoptotic cells can result in sustained inflammation and subsequent autoimmunity. Macrophages, the "professional phagocyte" of the body, are responsible for efficient, non-phlogistic, apoptotic cell clearance. Controlling phago
Externí odkaz:
https://doaj.org/article/121c70eecd334f97b1f6fa2901ad517d
Autor:
David W. Taft, Craig H. Moskowitz, Julie M. Vose, Tatyana Feldman, Qu Zhang, Keenan Fenton, Carol Anne Ogden, Ann S. LaCasce, Mary S. Campbell, Ranjana H. Advani, Alex F. Herrera, A.J. Moskowitz, Nancy L. Bartlett, Rod Ramchandren, S. M. Ansell, Kazunobu Kato
Publikováno v:
Hematological Oncology. 35:85-86
Autor:
Alison J. Moskowitz, Alex F. Herrera, Ann S. LaCasce, Julie M. Vose, Ranjana H. Advani, Keenan Fenton, Faith Galderisi, Beth A. Christian, Craig H. Moskowitz, Stephen M. Ansell, Radhakrishnan Ramchandren, David W. Taft, Mariana Sacchi, Daniel E. Zak, Tatyana Feldman, Nancy L. Bartlett, Carol Anne Ogden
Publikováno v:
Blood. 132:1635-1635
Introduction This phase 1/2 study evaluated the safety and antitumor activity of brentuximab vedotin (BV) administered in combination with nivolumab (Nivo) in adult patients (pts) with relapsed/refractory classic Hodgkin lymphoma (R/R cHL) who have f
Autor:
Christophe Combadière, John D. Pound, Gerard J. Graham, Lynsey Melville, Lucy A. Truman, Sarah J. Wilkinson, Ingrid E. Dumitriu, Marta Pasikowska, Christopher D. Gregory, Carol Anne Ogden, Robert J. B. Nibbs, Catriona A. Ford, Lauren A. Melrose
Publikováno v:
Blood. 112:5026-5036
Cells undergoing apoptosis are efficiently located and engulfed by phagocytes. The mechanisms by which macrophages, the professional scavenging phagocytes of apoptotic cells, are attracted to sites of apoptosis are poorly defined. Here we show that C
Autor:
Christopher D. Gregory, John D. Pound, Sarah Owens, Katrina M Wood, Carol Anne Ogden, Balvinder K. Batth, Ingolfur Johannessen
Publikováno v:
The Journal of Immunology. 174:3015-3023
Burkitt’s lymphoma (BL) is typified by frequent tumor cell apoptosis and significant macrophage infiltration. Since BL cells have an inherent tendency to undergo apoptosis at a high rate, we reasoned that macrophages in BL are functionally enhanced
Autor:
Christopher D. Gregory, Adam Lacy-Hulbert, Andrew Devitt, Christopher Bellamy, Ceri E. Oldreive, Michael Clay, Kate G. Parker, Carol Anne Ogden, Sophie C. Gangloff, Sanna M. Goyert, Lynsey Melville
Publikováno v:
The Journal of Cell Biology
Devitt, A, Parker, K G, Ogden, C A, Oldreive, C, Clay, M F, Melville, L A, Bellamy, C O, Lacy-Hulbert, A, Gangloff, S C, Goyert, S M & Gregory, C D 2004, ' Persistence of apoptotic cells without autoimmune disease or inflammation in CD14-/-mice ', Journal of Cell Biology, vol. 167, no. 6, pp. 1161-70 . https://doi.org/10.1083/jcb.200410057
Devitt, A, Parker, K G, Ogden, C A, Oldreive, C, Clay, M F, Melville, L A, Bellamy, C O, Lacy-Hulbert, A, Gangloff, S C, Goyert, S M & Gregory, C D 2004, ' Persistence of apoptotic cells without autoimmune disease or inflammation in CD14-/-mice ', Journal of Cell Biology, vol. 167, no. 6, pp. 1161-70 . https://doi.org/10.1083/jcb.200410057
Interaction of macrophages with apoptotic cells involves multiple steps including recognition, tethering, phagocytosis, and anti-inflammatory macrophage responses. Defective apoptotic cell clearance is associated with pathogenesis of autoimmune disea
Autor:
Alex F. Herrera, Alison J. Moskowitz, Nancy L. Bartlett, Julie M Vose, Radhakrishnan Ramchandren, Tatyana A Feldman, Ann S LaCasce, Stephen M Ansell, Craig H. Moskowitz, Keenan Fenton, Carol Anne Ogden, David Taft, Qu Zhang, Kazunobu Kato, Mary Campbell, Ranjana H. Advani
Publikováno v:
Blood. 130:649-649
Introduction Brentuximab vedotin (BV) is an ADC directed against CD30, a receptor expressed by malignant Reed-Sternberg (RS) cells present in the inflammatory/immune cell microenvironment of classical Hodgkin lymphomas (cHL). Through induction of imm
Autor:
Aimee deCathelineau, Berhane Ghebrehiwet, Valerie A. Fadok, Donna L. Bratton, Carol Anne Ogden, Peter R. Hoffmann, Peter M. Henson
Publikováno v:
The Journal of Experimental Medicine
Removal of apoptotic cells is essential for maintenance of tissue homeostasis, organogenesis, remodeling, development, and maintenance of the immune system, protection against neoplasia, and resolution of inflammation. The mechanisms of this removal
Autor:
Peter R. Hoffmann, Peter M. Henson, Aimee deCathelineau, Valerie A. Fadok, Donna L. Bratton, Carol Anne Ogden, Anne J. Ridley, David L. Daleke, Yann Leverrier
Publikováno v:
The Journal of Cell Biology
Efficient phagocytosis of apoptotic cells is important for normal tissue development, homeostasis, and the resolution of inflammation. Although many receptors have been implicated in the clearance of apoptotic cells, the roles of these receptors in t
Autor:
Ed Yurkow, Heather Deutsch, Ken Kilgore, Carol Anne Ogden, Karyn Cochlin, Zhao Zhou, Josh Wertheimer, Holly Raymond, Rachel A Bunting
Publikováno v:
Journal of Inflammation (London, England)
Human asthmatic disease is described as a chronic inflammatory disease of the airways. However, the underlying immunological processes involved in asthmatic disease are not fully understood. Animal models have been used to uncover patho-physiologic m