Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Carol Ann Aklonis"'
1
Bacillaene, a Novel Inhibitor of Procaryotic Protein Synthesis Produced by Bacillus subtilis: Production, Taxonomy, Isolation, Physico-chemical Characterization and Biological Activity
Autor: L. Dean, Dolores M. Pirnik, Carol Ann Aklonis, Pramathesh S. Patel, Friedrich Mayerl, Prabhavathi B. Fernandes, Stella Huang, Edward Meyers, Susan M. Fisher
Publikováno v: The Journal of Antibiotics. 48:997-1003
Bacillaene, a novel polyene antibiotic, was discovered and isolated from fermentation broths of a strain of Bacillus subtilis. The novel antibiotic has a nominal molecular weight of 580 and an empirical formula of C35H48O7. Bacillaene is active again
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c71416673aa3bbc2f0a18869090a4f
https://doi.org/10.7164/antibiotics.48.997
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3
Dactylocyclines: novel tetracycline glycosides active against tetracycline-resistant bacteria
Autor: Pacifico A. Principe, Alicia D. Kahle, Joseph O'sullivan, Mark S. Bolgar, Donald R. Kirsch, Carol Ann Aklonis, Michael A. Porubcan, Adrienne A. Tymiak, William H. Trejo
Publikováno v: The Journal of Organic Chemistry. 58:535-537
The dactylocycline antibiotics are a series of tetracycline glycosides with absolute stereochemistry at C-6 (R) unprecedented amongst natural tetracyclines which, in addition, display an unusual antibiotic spectrum
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0dc8441b306e32589719aa1028cc5e7b
https://doi.org/10.1021/jo00055a002
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4
Dactylocyclines, novel tetracycline derivatives produced by a Dactylosporangium sp. I. Taxonomy, production, isolation and biological activity
Autor: Adrienne A. Tymiak, P. Principe, Joseph O'sullivan, William H. Trejo, Donald R. Kirsch, J S Wells, Helen A. Ax, Carol Ann Aklonis
Publikováno v: The Journal of antibiotics. 45(12)
A screen for antibiotics with activity against tetracycline-resistant microorganisms has led to the isolation of Dactylosporangium sp. (ATCC 53693), a producer of several novel tetracycline derivatives. The major fermentation products, dactylocycline
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99abdf38892fdc082cff32cc381b2d5e
https://pubmed.ncbi.nlm.nih.gov/1490880
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5
Two new inhibitors of phospholipase A2 produced by Penicillium chermesinum. Taxonomy, fermentation, isolation, structure determination and biological properties
Autor: Joseph O'sullivan, Janice H. Johnson, Carol Ann Aklonis, Karen Bush, Pushpa D. Singh, Susan M. Fisher
Publikováno v: The Journal of Antibiotics. 38:706-712
Plastatin and the known fungal metabolite, luteosporin, have been isolated from fermentations of Penicillium chermesinum as inhibitors of porcine pancreatic phospholipase A2 (PLA2). Structure 1 for plastatin was deduced from its spectroscopic propert
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f398f85a2dcf0c5fb4078f6c42ec2b30
https://doi.org/10.7164/antibiotics.38.706
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7
SQ 30,957, a new antibiotic produced by Penicillium funiculosum. Taxonomy, fermentation, isolation, structure determination, synthesis and antibacterial activity
Autor: Carol Ann Aklonis, Janice H. Johnson, Joseph O'sullivan, Pushpa D. Singh
Publikováno v: The Journal of antibiotics. 39(8)
A new antibiotic, SQ 30,957, 4-diazo-3-methoxy-2,5-cyclohexadien-1-one, has been isolated from fermentation broths of Penicillium funiculosum. The structure (1) was deduced from its spectroscopic properties and its degradation reaction. SQ 30,957 has
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b4b9ccc0e919a030455f687007fd18
https://pubmed.ncbi.nlm.nih.gov/3759656
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