Zobrazeno 1 - 10
of 390
pro vyhledávání: '"Carol A. Williams"'
Autor:
Penelope C. Fialas, Lia R. V. Gilmour, Sophie Vickress, Emma Underwood, Carol A. Williams, Helen Miller, Paul R. Lintott
Publikováno v:
Ecology and Evolution, Vol 12, Iss 10, Pp n/a-n/a (2022)
Abstract Species‐specific responses to landscape configuration and landscape composition have been studied extensively. However, little work has been done to compare intraspecific differences in habitat preferences. Bats have potential as good bioi
Externí odkaz:
https://doaj.org/article/dc9246f5774846bea0a61bb1526ada46
Autor:
Shujuan Zhao, Kedous Y. Mekbib, Martijn A. van der Ent, Garrett Allington, Andrew Prendergast, Jocelyn E. Chau, Hannah Smith, John Shohfi, Jack Ocken, Daniel Duran, Charuta G. Furey, Le Thi Hao, Phan Q. Duy, Benjamin C. Reeves, Junhui Zhang, Carol Nelson-Williams, Di Chen, Boyang Li, Timothy Nottoli, Suxia Bai, Myron Rolle, Xue Zeng, Weilai Dong, Po-Ying Fu, Yung-Chun Wang, Shrikant Mane, Paulina Piwowarczyk, Katie Pricola Fehnel, Alfred Pokmeng See, Bermans J. Iskandar, Beverly Aagaard-Kienitz, Quentin J. Moyer, Evan Dennis, Emre Kiziltug, Adam J. Kundishora, Tyrone DeSpenza, Ana B. W. Greenberg, Seblewengel M. Kidanemariam, Andrew T. Hale, James M. Johnston, Eric M. Jackson, Phillip B. Storm, Shih-Shan Lang, William E. Butler, Bob S. Carter, Paul Chapman, Christopher J. Stapleton, Aman B. Patel, Georges Rodesch, Stanislas Smajda, Alejandro Berenstein, Tanyeri Barak, E. Zeynep Erson-Omay, Hongyu Zhao, Andres Moreno-De-Luca, Mark R. Proctor, Edward R. Smith, Darren B. Orbach, Seth L. Alper, Stefania Nicoli, Titus J. Boggon, Richard P. Lifton, Murat Gunel, Philip D. King, Sheng Chih Jin, Kristopher T. Kahle
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract To elucidate the pathogenesis of vein of Galen malformations (VOGMs), the most common and most severe of congenital brain arteriovenous malformations, we performed an integrated analysis of 310 VOGM proband-family exomes and 336,326 human ce
Externí odkaz:
https://doaj.org/article/3ca7b90963454521ac767ab9c7496a24
Autor:
Akansha S. Das, Emily C. Sherry, Robert M. Vaughan, Marian L. Henderson, Jacob Zieba, Katie L. Uhl, Olivia Koehn, Caleb P. Bupp, Surender Rajasekaran, Xiaopeng Li, Surya B. Chhetri, Sahar Nissim, Carol L. Williams, Jeremy W. Prokop
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The small GTPase family is well-studied in cancer and cellular physiology. With 162 annotated human genes, the family has a broad expression throughout cells of the body. Members of the family have multiple exons that require splicing. Yet, the role
Externí odkaz:
https://doaj.org/article/c07fd91f53d941d8a816a9e1ed070660
Autor:
Zeeshan Gauhar, Leon Tejwani, Uzma Abdullah, Sadia Saeed, Shagufta Shafique, Mazhar Badshah, Jungmin Choi, Weilai Dong, Carol Nelson-Williams, Richard P. Lifton, Janghoo Lim, Ghazala K. Raja
Publikováno v:
Cells, Vol 11, Iss 19, p 3090 (2022)
Autosomal-recessive cerebellar ataxias (ARCAs) are heterogeneous rare disorders mainly affecting the cerebellum and manifest as movement disorders in children and young adults. To date, ARCA causing mutations have been identified in nearly 100 genes;
Externí odkaz:
https://doaj.org/article/8b4eb39ce0dc404498614cfcd9839e1d
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Newly synthesized small GTPases in the Ras and Rho families are prenylated by cytosolic prenyltransferases and then escorted by chaperones to membranes, the nucleus, and other sites where the GTPases participate in a variety of signaling cascades. Un
Externí odkaz:
https://doaj.org/article/8cbf92727d3f4c0b93b41e6d4244e90d
Autor:
Adam J. Kundishora, Garrett Allington, Stephen McGee, Kedous Y. Mekbib, Vladimir Gainullin, Andrew T. Timberlake, Carol Nelson-Williams, Emre Kiziltug, Hannah Smith, Jack Ocken, John Shohfi, August Allocco, Phan Q. Duy, Aladine A. Elsamadicy, Weilai Dong, Shujuan Zhao, Yung-Chun Wang, Hanya M. Qureshi, Michael L. DiLuna, Shrikant Mane, Irina R. Tikhonova, Po-Ying Fu, Christopher Castaldi, Francesc López-Giráldez, James R. Knight, Charuta G. Furey, Bob S. Carter, Shozeb Haider, Andres Moreno-De-Luca, Seth L. Alper, Murat Gunel, Francisca Millan, Richard P. Lifton, Rebecca I. Torene, Sheng Chih Jin, Kristopher T. Kahle
Publikováno v:
Nature Medicine. 29:667-678
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ddcb39fe7c83d567c19dfb555a653bf
https://doi.org/10.1038/s41591-023-02238-2
https://doi.org/10.1038/s41591-023-02238-2
Autor:
Weilai Dong, Sheng Chih Jin, August Allocco, Xue Zeng, Amar H. Sheth, Shreyas Panchagnula, Annie Castonguay, Louis-Étienne Lorenzo, Barira Islam, Geneviève Brindle, Karine Bachand, Jamie Hu, Agata Sularz, Jonathan Gaillard, Jungmin Choi, Ashley Dunbar, Carol Nelson-Williams, Emre Kiziltug, Charuta Gavankar Furey, Sierra Conine, Phan Q. Duy, Adam J. Kundishora, Erin Loring, Boyang Li, Qiongshi Lu, Geyu Zhou, Wei Liu, Xinyue Li, Michael C. Sierant, Shrikant Mane, Christopher Castaldi, Francesc López-Giráldez, James R. Knight, Raymond F. Sekula, Jr., J. Marc Simard, Emad N. Eskandar, Christopher Gottschalk, Jennifer Moliterno, Murat Günel, Jason L. Gerrard, Sulayman Dib-Hajj, Stephen G. Waxman, Fred G. Barker, II, Seth L. Alper, Mohamed Chahine, Shozeb Haider, Yves De Koninck, Richard P. Lifton, Kristopher T. Kahle
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101552- (2020)
Summary: Trigeminal neuralgia (TN) is a common, debilitating neuropathic face pain syndrome often resistant to therapy. The familial clustering of TN cases suggests that genetic factors play a role in disease pathogenesis. However, no unbiased, large
Externí odkaz:
https://doaj.org/article/7d4dc8f9ca434d10935677d5c5a4aeb5
Structural and biophysical properties of farnesylated KRas interacting with the chaperone SmgGDS-558
Autor:
Dennis J. Michalak, Bethany Unger, Ellen Lorimer, Alexander Grishaev, Carol L. Williams, Frank Heinrich, Mathias Lösche
Publikováno v:
Biophysical Journal. 121:3684-3697
KRas is a small GTPase and membrane-bound signaling protein. Newly synthesized KRas is post-translationally modified with a membrane-anchoring prenyl group. KRas chaperones are therapeutic targets in cancer due to their participation in trafficking o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e97d687e3507616f4601946d5f3ab9
https://doi.org/10.1016/j.bpj.2022.05.028
https://doi.org/10.1016/j.bpj.2022.05.028
Autor:
Carol J. Williams
Publikováno v:
The Intellectual Dynamism of the High Middle Ages ISBN: 9789048537174
The Intellectual Dynamism of the High Middle Ages
The Intellectual Dynamism of the High Middle Ages
In Abelard’s Letter 16 addressed to ‘Héloise, sister to be revered in Christ and loved’, he refers to a set of six planctus or laments written in the voices of a number of Old Testament characters The last of these, Planctus 6, in which David
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0314768fa73db60f9a009a988cc47b
https://doi.org/10.1017/9789048537174.006
https://doi.org/10.1017/9789048537174.006
Autor:
Sheng Chih Jin, Charuta G. Furey, Xue Zeng, August Allocco, Carol Nelson‐Williams, Weilai Dong, Jason K. Karimy, Kevin Wang, Shaojie Ma, Eric Delpire, Kristopher T. Kahle
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 9, Pp n/a-n/a (2019)
Abstract Background Congenital hydrocephalus (CH) is a highly morbid disease that features enlarged brain ventricles and impaired cerebrospinal fluid homeostasis. Although early linkage or targeted sequencing studies in large multigenerational famili
Externí odkaz:
https://doaj.org/article/3db5cb3713634bbdb2d86ee4a140f6b9