Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Carol A. Wilke"'
Autor:
Giovanny J Martínez-Colón, Helen Warheit-Niemi, Stephen J Gurczynski, Quincy M Taylor, Carol A Wilke, Amy B Podsiad, Joel Crespo, Urvashi Bhan, Bethany B Moore
Publikováno v:
PLoS Pathogens, Vol 15, Iss 1, p e1007560 (2019)
Bacterial lung infections, particularly with methicillin-resistant Staphylococcus aureus (MRSA), increase mortality following influenza infection, but the mechanisms remain unclear. Here we show that expression of TLR9, a microbial DNA sensor, is inc
Externí odkaz:
https://doaj.org/article/51ceb92af3b2453281765c18d108805a
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139235 (2015)
Adenovirus infections are important complications of bone marrow transplantation (BMT). We demonstrate delayed clearance of mouse adenovirus type 1 (MAV-1) from lungs of mice following allogeneic BMT. Virus-induced prostaglandin E2 (PGE2) production
Externí odkaz:
https://doaj.org/article/d5cdef6e0733499dbf7650a841f49d6b
Autor:
Brigid M O'Flaherty, Caline G Matar, Brian S Wakeman, AnaPatricia Garcia, Carol A Wilke, Cynthia L Courtney, Bethany B Moore, Samuel H Speck
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135719 (2015)
Idiopathic pulmonary fibrosis (IPF), one of the most severe interstitial lung diseases, is a progressive fibrotic disorder of unknown etiology. However, there is growing appreciation for the role of viral infection in disease induction and/or progres
Externí odkaz:
https://doaj.org/article/26e2f085e64b40dba44c54569fbf2304
Autor:
Kevin Sekerak, Paul R Chan, Holly K. Miller, Susan Murray, Xiaofeng Zhou, Carol A. Wilke, Camille Bulte, Meng Xia, Timothy Hoffman, David N O'Dwyer, Bethany B. Moore, Mathew M Chadwick, Wayne M. Yokoyama, Gregory A. Yanik, Kelsey Trulik, Swapneel J. Patel
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 200:63-74
Rationale: “Noninfectious” pulmonary complications are significant causes of morbidity and mortality after allogeneic hematopoietic cell transplant. Early-onset viral reactivations or infections ar...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::061d8a108b78488de50abc15dde85042
https://doi.org/10.1164/rccm.201809-1635oc
https://doi.org/10.1164/rccm.201809-1635oc
Autor:
Meng Xia, Susan Murray, Gary B. Huffnagle, Katy C. Norman, Eric S. White, Margaret L. Salisbury, Fernando J. Martinez, MeiLan K. Han, Robert P. Dickson, John R. Erb-Downward, Carol A. Wilke, Shanna L. Ashley, David N O'Dwyer, Bethany B. Moore, Stephen J. Gurczynski, Kelly B. Arnold, Nicole R. Falkowski, Kevin R. Flaherty
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Am J Respir Crit Care Med
Am J Respir Crit Care Med
Rationale: Idiopathic pulmonary fibrosis (IPF) causes considerable global morbidity and mortality, and its mechanisms of disease progression are poorly understood. Recent observational studies have reported associations between lung dysbiosis, mortal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779ede6fef94b8db72f807e9a384866a
https://doi.org/10.1164/rccm.201809-1650oc
https://doi.org/10.1164/rccm.201809-1650oc
Autor:
Courtney Hames, Thomas F. Michniacki, Andrea J. Hartlerode, Rudel A. Saunders, Carol A. Wilke, Hilary A. Moale, JoAnn Sekiguchi, Bethany B. Moore, Molly E. Kuo, Johnathan Nguyen
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Ataxia-telangiectasia (A-T) is an autosomal recessive, multisystem disorder characterized by cerebellar degeneration, cancer predisposition, and immune system defects. A major cause of mortality in A-T patients is severe pulmonary disease; however, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87bbea8b5f636f3cc7c7dff97112f76d
https://doi.org/10.1038/s41598-021-83531-3
https://doi.org/10.1038/s41598-021-83531-3
Autor:
Aaron denDekker, Bethany B. Moore, William J. Melvin, Steven K. Huang, Katherine A. Gallagher, Steven L. Kunkel, Hongping Deng, Andrew M. Smith, Rachael Wasikowski, Sonya J. Wolf, Stephan Weidinger, Amrita Joshi, Carol A. Wilke, Christopher O. Audu, Jay H Lipinski, Andrea T. Obi, Johann E. Gudjonsson, Frank M. Davis, Scott T. Robinson, Lam C. Tsoi, Allison C. Billi
Publikováno v:
JCI Insight, Vol 5, Iss 17 (2020)
JCI Insight
JCI Insight
Macrophages are a primary immune cell involved in inflammation, and their cell plasticity allows for transition from an inflammatory to a reparative phenotype and is critical for normal tissue repair following injury. Evidence suggests that epigeneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2013fa4c3f838808a0415491c068a9
https://doaj.org/article/f96a2c186aa440dc9e0a0bd22363cca4
https://doaj.org/article/f96a2c186aa440dc9e0a0bd22363cca4
Autor:
Catrina E Latuszek, Carol A. Wilke, Loka R. Penke, Joel A. Swanson, Daniel J. Schneider, Bethany B. Moore, Katherine A Smith, Jennifer M. Speth, Matangi Marthi, Daniel M. Lyons, Marc Peters-Golden, Adam S. Lauring
Publikováno v:
EMBO J
Alveolar macrophages (AMs) and epithelial cells (ECs) are the lone resident lung cells positioned to respond to pathogens at early stages of infection. Extracellular vesicles (EVs) are important vectors of paracrine signaling implicated in a range of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a1eaa15bff867c90457e29291eef0a
https://doi.org/10.15252/embj.2020105057
https://doi.org/10.15252/embj.2020105057
Autor:
Stephen J. Gurczynski, Lonnie D. Shea, Bethany B. Moore, Eiji Saito, Kevin R. Kramer, Stephen D. Miller, Carol A. Wilke
Publikováno v:
Science Advances
Noninvasive pulmonary delivery of antigen-specific nanoparticles can modulate lung immune responses to treat autoimmune diseases.
Antigen-specific particles can treat autoimmunity, and pulmonary delivery may provide for easier delivery than intr
Antigen-specific particles can treat autoimmunity, and pulmonary delivery may provide for easier delivery than intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca9c1e8d861aac540c73301273c2f1b
https://pubmed.ncbi.nlm.nih.gov/33067238
https://pubmed.ncbi.nlm.nih.gov/33067238
Autor:
Stephen J. Gurczynski, Nicolas L Pereira, Steven M. Hrycaj, Bethany B. Moore, Carol A. Wilke, Rachel L. Zemans
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 2 (2021)
JCI Insight, Vol 6, Iss 2 (2021)
The aryl-hydrocarbon receptor (AHR) is an intracellular sensor of aromatic hydrocarbons that sits at the top of various immunomodulatory pathways. Here, we present evidence that AHR plays a role in controlling IL-17 responses and the development of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28beaa9ec24b2c453dd4e089cdc82bc8
https://pubmed.ncbi.nlm.nih.gov/33491663
https://pubmed.ncbi.nlm.nih.gov/33491663