Zobrazeno 1 - 10
of 721
pro vyhledávání: '"Carol A. Pollock"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Obesity increases the risk of chronic kidney disease. We have previously demonstrated the benefits of preconception maternal weight loss on fertility and pregnancy outcomes in a mouse model of maternal obesity. Here, we elucidate if preconce
Externí odkaz:
https://doaj.org/article/b4c6883587bc4a228a3521de8347c398
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Peripheral blood RNA profiling, which can reveal systemic changes in gene expression and immune responses to disease onset and progression, is a powerful tool for diagnosis and biomarker discovery. This technique usually requires high qualit
Externí odkaz:
https://doaj.org/article/55414b83f4324e4cab5fa69fa6f36fe8
Autor:
Reza Mohebi, Yuxi Liu, Michael K. Hansen, Yshai Yavin, Naveed Sattar, Carol A. Pollock, Javed Butler, Meg Jardine, Serge Masson, Hiddo J. L. Heerspink, James L. Januzzi Jr
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-8 (2023)
Abstract Background The insulin-like growth factors (IGF) play a crucial role in regulating cellular proliferation, apoptosis, and key metabolic pathways. The ratio of IGF-1 to IGF binding protein-3 (IGFBP-3) is an important factor in determining IGF
Externí odkaz:
https://doaj.org/article/8d86d7f7e1444d2a90066025dc652fd2
Autor:
Amanda R. Purcell, Natassia Rodrigo, Qinghua Cao, Olivia Joseph, Anthony J. Gill, Sonia Saad, Carol A. Pollock, Sarah J. Glastras
Publikováno v:
Nutrients, Vol 16, Iss 1, p 109 (2023)
Early-life exposure to maternal obesity predisposes offspring to metabolic-associated fatty liver disease (MAFLD). This study aimed to determine if peripartum weight loss, either through dietary intervention or pharmacological intervention, improved
Externí odkaz:
https://doaj.org/article/496c9c6857b744e2905bb04f3a8385a8
Publikováno v:
Nutrients, Vol 15, Iss 19, p 4207 (2023)
The developmental programming hypothesis proposes that adverse environmental insults during critical developmental periods increase the risk of diseases later in life. The kidneys are deemed susceptible to such a process, although the exact mechanism
Externí odkaz:
https://doaj.org/article/cb94f2baaa3543f790617bca9241fe7e
Autor:
Min Feng, Xu Bai, Andrew E. Thorpe, Long The Nguyen, Meng Wang, Brian G. Oliver, Angela S. Y. Chou, Carol A. Pollock, Sonia Saad, Hui Chen
Publikováno v:
Nutrients, Vol 15, Iss 14, p 3140 (2023)
High-fat diet (HFD) consumption and tobacco smoking are risk factors for chronic kidney disease. E-cigarettes have gained significant popularity among younger populations worldwide, especially among overweight individuals. It is unclear whether vapin
Externí odkaz:
https://doaj.org/article/0c16b21446ec4ee0bc1ae1a9a6d74f15
Autor:
Long T. Nguyen, Sonia Saad, Ying Shi, Rosy Wang, Angela S. Y. Chou, Anthony Gill, Yimin Yao, Wolfgang Jarolimek, Carol A. Pollock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Calcineurin inhibitors, such as Cyclosporin (CsA), are the mainstay of anti-rejection therapy in solid organ transplants but can paradoxically induce progressive nephropathy characterised by renal dysfunction and interstitial fibrosis. Lysyl
Externí odkaz:
https://doaj.org/article/1d8b0be6924f440380930771f436d6c4
Autor:
Saabah B. Mahbub, Long T. Nguyen, Abbas Habibalahi, Jared M. Campbell, Ayad G. Anwer, Uzair M. Qadri, Anthony Gill, Angela Chou, Muh Geot Wong, Martin E. Gosnell, Carol A. Pollock, Sonia Saad, Ewa M. Goldys
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Optimally preserved urinary exfoliated renal proximal tubule cells were assessed by multispectral imaging of cell autofluorescence. We demonstrated different multispectral autofluorescence signals in such cells extracted from the urine of pa
Externí odkaz:
https://doaj.org/article/5443aeae1749467793671f947216d1cc
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Long term e-cigarette vaping induces inflammation, which is largely nicotine independent. High-fat diet (HFD) consumption is anoter cause of systemic low-grade inflammation. The likelihood of using e-cigarettes as a weight control strategy is concomi
Externí odkaz:
https://doaj.org/article/55a4bef73f31439885bc30dc3be2258b
Autor:
Umut Rende, Seong Beom Ahn, Subash Adhikari, Edward S. X. Moh, Carol A. Pollock, Sonia Saad, Anna Guller
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2827 (2023)
Precise characterization of a tissue’s extracellular matrix (ECM) protein composition (matrisome) is essential for biomedicine. However, ECM protein extraction that requires organ-specific optimization is still a major limiting factor in matrisome
Externí odkaz:
https://doaj.org/article/ed2cd56720034aca871cfa78dd787b00