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Autor:
Lorraine Lipfert, Gideon A. Rodan, John H. Hutchinson, Bradley P. Feuston, Kara Merkle, Donald B. Kimmel, Thomayant Prueksaritanont, Mark E. Duggan, Carol A. Mcvean, Chih-Tai Leu, Gregg Wesolowski, Brenda L Pennypacker, Michael A. Gentile, Ben C. Askew, Sevgi B. Rodan, Le T. Duong, Karen M. Brashear, Carmen Fernandez-Metzler, Paul J. Coleman, George D. Hartman
Publikováno v:
Journal of Medicinal Chemistry. 47:4829-4837
3-(S)-Pyrimidin-5-yl-9-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-nonanoic acid (5e) and 3-(S)-(methylpyrimidin-5-yl)-9-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-nonanoic acid (5f) were identified as potent and selective antagonists of the alpha(v