Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Carol A. Lange-Carter"'
Publikováno v:
Journal of Biological Chemistry. 270:11757-11760
Mitogen-activated protein kinase kinase kinase (MEKK1) is a serine-threonine kinase that regulates sequential protein kinase pathways involving stress-activated protein kinases and mitogen-activated protein kinases. MEKK1 is activated in response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd968408b7c3d97d955e02cd14e508a
https://doi.org/10.1074/jbc.270.20.11757
https://doi.org/10.1074/jbc.270.20.11757
Autor:
Anning Lin, Audrey Minden, Frank Mercurio, Francois Xavier Claret, Gary L. Johnson, Horacio Martinetto, Michael Karin, Carol A. Lange-Carter
Publikováno v:
Science. 268:286-290
One Ras-dependent protein kinase cascade leading from growth factor receptors to the ERK (extracellular signal-regulated kinases) subgroup of mitogen-activated protein kinases (MAPKs) is dependent on the protein kinase Raf-1, which activates the MEK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bf842b352b3185a4b77ba797a475cc
https://doi.org/10.1126/science.7716521
https://doi.org/10.1126/science.7716521
Autor:
Carol A. Lange-Carter, Anne M. Gardner, Brent W. Winston, Gary L. Johnson, David W. H. Riches
Publikováno v:
Proceedings of the National Academy of Sciences. 92:1614-1618
Tumor necrosis factor alpha (TNF alpha) is bound by two cell surface receptors, CD120a (p55) and CD120b (p75), that belong to the TNF/nerve growth factor receptor family and whose signaling is initiated by receptor multimerization in the plane of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fb8b9609e32929ae07a65d9b867449
https://doi.org/10.1073/pnas.92.5.1614
https://doi.org/10.1073/pnas.92.5.1614
Autor:
Michael Karin, Benoit Dérijard, Carol A. Lange-Carter, Roger J. Davis, Anning Lin, Martin McMahon, Gary L. Johnson, Audrey Minden
Publikováno v:
Science. 266:1719-1723
Growth factors activate mitogen-activated protein kinases (MAPKs), including extracellular signal-regulated kinases (ERKs) and Jun kinases (JNKs). Although the signaling cascade from growth factor receptors to ERKs is relatively well understood, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ade21347db7975c75b59d550d5aca2c
https://doi.org/10.1126/science.7992057
https://doi.org/10.1126/science.7992057
Autor:
Sim Winitz, Carol A. Lange-Carter, Anne M. Gardner, Gary L. Johnson, Marijane Russell, Nan‐Xin ‐X Qian
Publikováno v:
Journal of Cellular Biochemistry. 54:415-422
Serpentine receptors coupled to the heterotrimeric G protein, Gi2, are capable of stimulating DNA synthesis in a variety of cell types. A common feature of the Gi2-coupled stimulation of DNA synthesis is the activation of the mitogen-activated protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d38531da81f9876e88d0ad5e1b904c
https://doi.org/10.1002/jcb.240540408
https://doi.org/10.1002/jcb.240540408
Publikováno v:
Science. 260:315-319
Mitogen-activated protein kinases (MAPKs) are rapidly phosphorylated and activated in response to various extracellular stimuli in many different cell types. Such regulation of MAPK results from sequential activation of a series of protein kinases. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803306539b3962ec05508c116e33ebc0
https://doi.org/10.1126/science.8385802
https://doi.org/10.1126/science.8385802
Publikováno v:
Cancer Letters. 67:139-144
We examined the responsiveness of normal and neoplastic lung cells to agents which stimulate cAMP production. While their basal cAMP levels were similar, spontaneous in vitro transformant E9 cells and tumor-derived PCC4 cells produced much less cAMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88676a1c39c0894f98dda0ea79290205
https://doi.org/10.1016/0304-3835(92)90137-k
https://doi.org/10.1016/0304-3835(92)90137-k
Autor:
Katrina M. Diener, Michael Karin, Janice Gleavy, Carol A. Lange-Carter, Audrey Minden, Anne M. Gardner, Gary L. Johnson, Matthew B. Jarpe, Leonard I. Zon, Nancy Lassignal Johnson
Publikováno v:
The Journal of biological chemistry. 271(6)
Mitogen-activated/extracellular response kinase kinase (MEK) kinase (MEKK) is a serine-threonine kinase that regulates sequential protein phosphorylation pathways, leading to the activation of mitogen-activated protein kinases (MAPK), including membe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df715d2e8e8feb4d4f1ab99b5aa046aa
https://pubmed.ncbi.nlm.nih.gov/8621725
https://pubmed.ncbi.nlm.nih.gov/8621725
MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase
Autor:
Melanie H. Cobb, Jeffrey A. Frost, David J. Robbins, Carol A. Lange-Carter, Shuichan Xu, Alphonsus Dang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 92(15)
A constitutively active fragment of rat MEK kinase 1 (MEKK1) consisting of only its catalytic domain (MEKK-C) expressed in bacteria quantitatively activates recombinant mitogen-activated protein (MAP) kinase/extracellular signal-regulated protein kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4651f4efb252b92bcc420926d621cd
https://pubmed.ncbi.nlm.nih.gov/7624324
https://pubmed.ncbi.nlm.nih.gov/7624324
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 91(11)
Mitogen-activated protein kinase cascades are conserved in fungal, plant, and metazoan species. We expressed murine MAP kinase kinase kinase (MEKK) in the yeast Saccharomyces cerevisiae to determine whether this kinase functions as a general or speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd884a33ff32fbd45e40620d867bed6c
https://pubmed.ncbi.nlm.nih.gov/8197159
https://pubmed.ncbi.nlm.nih.gov/8197159