Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Carol A Lange"'
Autor:
Alfredo A Molinolo, Junping Wei, Xiao-Yi Yang, Gangjun Lei, Zachary C Hartman, Lauryn R Werner, Katelin A Gibson, Merit L Goodman, Dominika E Helm, Katherine R Walter, Sean M Holloran, Gloria M Trinca, Richard C Hastings, Howard H Yang, Rashna Madan, Mary A Markiewicz, Prabhakar Chalise, Margaret L Axelrod, Justin M Balko, Kent W Hunter, Carol A Lange, Christy R Hagan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Clinical studies have linked usage of progestins (synthetic progesterone [P4]) to breast cancer risk. However, little is understood regarding the role of native P4, signaling through the progesterone receptor (PR), in breast tumor formatio
Externí odkaz:
https://doaj.org/article/3ebc51e37c9e47cf891b9468adc3f631
Autor:
Carlos Jesus Perez Kerkvliet, Amy R Dwyer, Caroline Diep, Robert Oakley, Christopher Liddle, Carol A Lange
Publikováno v:
Journal of Clinical and Translational Science, Vol 4, Pp 7-8 (2020)
OBJECTIVES/GOALS: The glucocorticoid receptor (GR) is a ubiquitous steroid hormone receptor that is emerging as a mediator of breast cancer metastasis. We aim to better understand the biology associated with phospho-GR species in TNBC and their contr
Externí odkaz:
https://doaj.org/article/409bca312f104e95af1b59b8a069adf8
Publikováno v:
PLoS Genetics, Vol 13, Iss 9, p e1006973 (2017)
Breast cancer is the second largest cause of cancer death among U.S. women and the leading cause of cancer death among women worldwide. Genome-wide association studies (GWAS) have identified several genetic variants associated with susceptibility to
Externí odkaz:
https://doaj.org/article/73987741c702409093c4fecf59bbf22b
Autor:
Amy R Dwyer, Carlos Perez Kerkvliet, Thu H Truong, Kyla M Hagen, Raisa I Krutilina, Deanna N Parke, Robert H Oakley, Christopher Liddle, John A Cidlowski, Tiffany N Seagroves, Carol A Lange
Publikováno v:
Endocrinology.
Corticosteroids act on the glucocorticoid receptor (GR; NR3C1) to resolve inflammation and are routinely prescribed to breast cancer patients undergoing chemotherapy treatment to alleviate side effects. Triple negative breast cancers (TNBCs) account
Autor:
Morag J. Young, Nancy Weigel, Marc Tetel, Carol A. Sartorius, Jennifer K. Richer, Robert H. Oakley, Carol A. Lange, Sean Hartig, Sandra L. Grimm, Peter Fuller, Dean P. Edwards, John Cidlowski, Derek Cain
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Steroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [75, 218, 3]) are nuclear hormone receptors of the NR3 class, with endogenous agonists that may be divided into 3-hydroxysteroids (estrone an
Autor:
Sarah E Tarullo, Yuyu He, Claire Daughters, Todd P Knutson, Christine M Henzler, Matthew A Price, Ryan Shanley, Patrice Witschen, Cornelia Tolg, Rachael E Kaspar, Caroline Hallstrom, Lyubov Gittsovich, Megan L Sulciner, Xihong Zhang, Colleen L Forster, Carol A Lange, Oleg Shats, Michelle Desler, Kenneth H Cowan, Douglas Yee, Kathryn L Schwertfeger, Eva A Turley, James B McCarthy, Andrew C Nelson
Publikováno v:
The Journal of Pathology.
Supplemental Figures Legends 1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1dbc37ade8318319b01be2129ce177
https://doi.org/10.1158/1541-7786.22512070
https://doi.org/10.1158/1541-7786.22512070
FOXO1 enhances PR Ser294 phosphorylation in PR-B+ cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d193cf5f8e4e38920349357884eefd
https://doi.org/10.1158/1541-7786.22512055.v1
https://doi.org/10.1158/1541-7786.22512055.v1
Autor:
Carol A. Lange, Tiffany N. Seagroves, Kathryn L. Schwertfeger, Julie H. Ostrander, John A. Cidlowski, Ganesh V. Raj, Raisa I. Krutilina, Taylor M. Helle, Yan Peng, Carlos Perez Kerkvliet, Shihong Ma, Tarah M. Regan Anderson
Western blot of MDA-MB-231 parental or HIF DKO cells demonstrating loss of regulation of PELP1 expression in response to taxol treatment in cells with HIF double-knockout.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018a32d865189c97f4ef83ef8af040be
https://doi.org/10.1158/1541-7786.22511061.v1
https://doi.org/10.1158/1541-7786.22511061.v1
PR-A-induced cellular senescence is dependent on FOXO1 activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0c8dd0288bc7af8afbe1eac0cb8a4b
https://doi.org/10.1158/1541-7786.22512061
https://doi.org/10.1158/1541-7786.22512061