Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Carol A Fierke"'
Autor:
Peng-Hsun Chase Chen, Xuejiao Shirley Guo, Hanyuan Eric Zhang, Gopal K. Dubey, Zhi Zachary Geng, Carol A. Fierke, Shiqing Xu, J. Trae Hampton, Wenshe Ray Liu
Publikováno v:
ACS Central Science, Vol 10, Iss 4, Pp 782-792 (2024)
Externí odkaz:
https://doaj.org/article/d71941143edf450a9bfc51584dc72d67
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 10, p e1002170 (2011)
Farnesylation is an important post-translational modification catalyzed by farnesyltransferase (FTase). Until recently it was believed that a C-terminal CaaX motif is required for farnesylation, but recent experiments have revealed larger substrate d
Externí odkaz:
https://doaj.org/article/97d6d25ef4454004a05012b159a532b5
Autor:
Kai S. Yang, Lauren R. Blankenship, Syuan-Ting Alex Kuo, Yan J. Sheng, Pingwei Li, Carol A. Fierke, David H. Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu
Publikováno v:
ACS Chemical Biology. 18:449-455
Autor:
Peng-Hsun Chase Chen, Xuejiao Shirley Guo, Hanyuan Eric Zhang, Zhi Zachary Geng, Gopal K. Dubey, Carol A. Fierke, Shiqing Xu, Wenshe Ray Liu
Eleven-nineteen leukemia protein (ENL) plays pivotal roles in the leukemogenesis. As a YEATS domain protein, ENL reads histone acylation marks and recruits key transcription factors to leukemic drivers such asHOXA9, MEIS1, andMYBand therefore promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8011bc08b842f636212162257b403913
https://doi.org/10.1101/2023.01.08.523168
https://doi.org/10.1101/2023.01.08.523168
Autor:
Jared S. Morse, Yan J. Sheng, Joshua Trae Hampton, Lauralee D. Sylvain, Sukant Das, Yugendar R. Alugubelli, Peng‐Hsun Chase Chen, Kai S. Yang, Shiqing Xu, Carol A. Fierke, Wenshe Ray Liu
Publikováno v:
Protein Science. 31
Phage-assisted, active site-directed ligand evolution (PADLE) is a recently developed technique that uses an amber codon-encoded noncanonical amino acid (ncAA) as an anchor to direct phage-displayed peptides to a target for an enhanced ligand identif
Publikováno v:
International Journal of Nanomedicine
Di Si,1 Guochao Nie,2â 4 Tamiika K Hurst,1 Carol A Fierke,1 Raoul Kopelman1 1Department of Chemistry, University of Michigan, Ann Arbor, MI, USA; 2School of Physics and Telecommunication Engineering, Yulin Normal University, Yulin, Peopleâs
The first step in transfer RNA (tRNA) maturation is the cleavage of the 5’ end of precursor transfer RNA (pre-tRNA) catalyzed by ribonuclease P (RNase P). RNase P is either a ribonucleoprotein (RNP) complex with a catalytic RNA subunit or aprotein-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8cd1aba9dec374a3660dfc93f3b2322
https://doi.org/10.1101/2022.10.20.512141
https://doi.org/10.1101/2022.10.20.512141
Autor:
Jared S. Morse, Yan J. Sheng, J. Trae Hampton, Lauralee D. Sylvain, Sukant Das, Yugendar R. Alugubelli, Peng-Hsun Chase Chen, Kai S. Yang, Shiqing Xu, Carol A. Fierke, Wenshe Ray Liu
The phage-assisted, active site-directed ligand evolution (PADLE) is a recently developed technique that uses an amber codon-encoded noncanonical amino acid (ncAA) as an anchor to direct phage-displayed peptides to a target for an enhanced ligand ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6bd525d84b0b2f9d07d7846bcd96523
https://doi.org/10.1101/2022.09.14.508049
https://doi.org/10.1101/2022.09.14.508049
Discovering RNA-Protein Interactome by Using Chemical Context Profiling of the RNA-Protein Interface
Autor:
Marc Parisien, Xiaoyun Wang, George Perdrizet, II, Corissa Lamphear, Carol A. Fierke, Ketan C. Maheshwari, Michael J. Wilde, Tobin R. Sosnick, Tao Pan
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1703-1713 (2013)
RNA-protein (RNP) interactions generally are required for RNA function. At least 5% of human genes code for RNA-binding proteins. Whereas many approaches can identify the RNA partners for a specific protein, finding the protein partners for a specifi
Externí odkaz:
https://doaj.org/article/efd1fe3de01248769cbc26442ef46592
Autor:
Carol F Fierke, Marcetta Y. Darensbourg, Hanyuan Zhang, Christopher R DeLaney, Nattamai Bhuvanesh, Wenshe R Liu, Isaiah Salas, Yan Sheng, Erol Vantansever, D Chase Pectol
Publikováno v:
Dalton Transactions. 50:12226-12233
Numerous organic molecules are known to inhibit the main protease of SARS-CoV-2, (SC2Mpro), a key component in viral replication of the 2019 novel coronavirus. We explore the hypothesis that zinc ions, long used as a medicinal supplement and known to