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Akademický článek

Prediction of Intracranial Hypertension and Brain Tissue Hypoxia Utilizing High-Resolution Data from the BOOST-II Clinical Trial

Publikováno v: Neurotrauma Reports, Vol 3, Iss 1, Pp 473-478 (2022)

The current approach to intracranial hypertension and brain tissue hypoxia is reactive, based on fixed thresholds. We used statistical machine learning on high-frequency intracranial pressure (ICP) and partial brain tissue oxygen tension (PbtO2) data

Externí odkaz: https://doaj.org/article/b7b0ceeeec8f45bb94a2d9e155ccbd39

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Akademický článek

Cerebrovascular Reactivity Measures Are Associated With Post-traumatic Headache Severity in Chronic TBI; A Retrospective Analysis

Autor: Franck Amyot, Cillian E. Lynch, John Ollinger, J. Kent Werner, E. Silverman, Carol Moore, Cora Davis, L. Christine Turtzo, Ramon Diaz-Arrastia, Kimbra Kenney

Publikováno v: Frontiers in Physiology, Vol 12 (2021)

ObjectiveTo characterize the relationship between persistent post-traumatic headache (pPTH) and traumatic cerebrovascular injury (TCVI) in chronic traumatic brain injury (TBI). Cerebrovascular reactivity (CVR), a measure of the cerebral microvasculat

Externí odkaz: https://doaj.org/article/932137137efd41a292d6f08215b4bdc6

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Akademický článek

Assessment of cerebrovascular dysfunction after traumatic brain injury with fMRI and fNIRS

Autor: Franck Amyot, Kimbra Kenney, Emily Spessert, Carol Moore, Margalit Haber, Erika Silverman, Amir Gandjbakhche, Ramon Diaz-Arrastia

Publikováno v: NeuroImage: Clinical, Vol 25, Iss , Pp - (2020)

Traumatic cerebral vascular injury (TCVI) is a frequent, but under-recognized, endophenotype of traumatic brain injury (TBI). It likely contributes to functional deficits after TBI and TBI-related chronic disability, and represents an attractive targ

Externí odkaz: https://doaj.org/article/05cf9a4b3a5041839f139d8420622a03

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Akademický článek

Evolution of Traumatic Parenchymal Intracranial Hematomas (ICHs): Comparison of Hematoma and Edema Components

Autor: Sean Wilkes, Erin McCormack, Kimbra Kenney, Brian Stephens, Ross Passo, Leah Harburg, Erika Silverman, Carol Moore, Tanya Bogoslovsky, Dzung Pham, Ramon Diaz-Arrastia

Publikováno v: Frontiers in Neurology, Vol 9 (2018)

This study seeks to quantitatively assess evolution of traumatic ICHs over the first 24 h and investigate its relationship with functional outcome. Early expansion of traumatic intracranial hematoma (ICH) is common, but previous studies have focused

Externí odkaz: https://doaj.org/article/79065f78b28a4e608ae60981deb16751

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Cerebrovascular Reactivity Measurement with Functional Near Infrared Spectroscopy

Autor: Kimbra Kenney, Ramon Diaz-Arrastia, Amir Gandjbakhche, Erika Silverman, Carol Moore, Mike Sangobowale, Cora Davis, Franck Amyot

Publikováno v: Journal of visualized experiments : JoVE. (184)

Cerebrovascular reactivity (CVR) is the capacity of blood vessels in the brain to alter cerebral blood flow (either with dilation or constriction) in response to chemical or physical stimuli. The amount of reactivity in the cerebral microvasculature

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e093a4b45212f1d24ef4cfd016c4d7f9
https://pubmed.ncbi.nlm.nih.gov/35723463

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Activation of the Calcium Receptor by Calcimimetic Agents Is Preserved Despite Modest Attenuating Effects of Hyperphosphatemia

Autor: James Lai, Edward F. Nemeth, Kevin J. Martin, Jiahong Xu, Debra Drayer, Donald T. Ward, Carol Moore, William G. Goodman, Yun Chon

Publikováno v: J Am Soc Nephrol
Goodman, W G, Ward, D T, Martin, K J, Drayer, D, Moore, C, Xu, J, Lai, J, Chon, Y & Nemeth, E F 2022, ' Activation of the Calcium Receptor by Calcimimetic Agents Is Preserved Despite Modest Attenuating Effects of Hyperphosphatemia ', Journal of the American Society of Nephrology : JASN, vol. 33, no. 1, pp. 201-212 . https://doi.org/10.1681/ASN.2021060825

BACKGROUND: Phosphorus levels in the range seen clinically among patients undergoing dialysis have been reported to attenuate calcium receptor activation and modify parathyroid hormone (PTH) release from isolated parathyroid glands in vitro. Some cli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4159c89124255059d327b10b8253af7
https://europepmc.org/articles/PMC8763177/

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Cerebrovascular Reactivity Measures Are Associated With Post-traumatic Headache Severity in Chronic TBI; A Retrospective Analysis

Autor: Carol Moore, Cillian E Lynch, Cora Davis, John Ollinger, L. Christine Turtzo, Ramon Diaz-Arrastia, Franck Amyot, Erika Silverman, J Kent Werner, Kimbra Kenney

Publikováno v: Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226e8c5b605d7dbe23198d9155f2b69c
https://doi.org/10.3389/fphys.2021.649901

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Akademický článek

Trends in US Hospital Admissions for Skin and Soft Tissue Infections

Autor: John Edelsberg, Charu Taneja, Marcus Zervos, Nadia Haque, Carol Moore, Katherine Reyes, James Spalding, Jenny Jiang, Gerry Oster

Publikováno v: Emerging Infectious Diseases, Vol 15, Iss 9, Pp 1516-1518 (2009)

Using data from the 2000–2004 US Healthcare Cost and Utilization Project National Inpatient Sample, we found that total hospital admissions for skin and soft tissue infections increased by 29% during 2000–2004; admissions for pneumonia were large

Externí odkaz: https://doaj.org/article/694c6b7a747d4c178282176c8d85f4ce

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Imaging biomarkers of vascular and axonal injury are spatially distinct in chronic traumatic brain injury

Autor: Danielle K. Sandsmark, Kimbra Kenney, Ramon Diaz-Arrastia, Dzung L. Pham, John K Werner, Margalit Haber, Yiyu Chou, Sarah Woodson, Carol Moore, Erika Silverman, Cillian E Lynch, Franck Amyot, Kelley Flesher

Publikováno v: J Cereb Blood Flow Metab

Traumatic Brain Injury (TBI) is associated with both diffuse axonal injury (DAI) and diffuse vascular injury (DVI), which result from inertial shearing forces. These terms are often used interchangeably, but the spatial relationships between DAI and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c511aa3cf79dc71977a0ea9f1b0abf08
https://pubmed.ncbi.nlm.nih.gov/33444092

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Vascular Abnormalities within Normal Appearing Tissue in Chronic Traumatic Brain Injury

Autor: Danielle K. Sandsmark, Carol Moore, John A. Butman, Erika Silverman, Kimbra Kenney, Jamie E Podell, Ramon Diaz-Arrastia, Hanzhang Lu, Dzung L. Pham, Franck Amyot, Tawny Meredith-Duliba, Yi Yu Chou, Margalit Haber

Publikováno v: Journal of Neurotrauma. 35:2250-2258

Magnetic resonance imaging (MRI) is a powerful tool for visualizing traumatic brain injury(TBI)-related lesions. Trauma-induced encephalomalacia is frequently identified by its hyperintense appearance on fluid-attenuated inversion recovery (FLAIR) se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232d730f458db6b75c533b742de5a7d4
https://doi.org/10.1089/neu.2018.5684

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