The development of a non-invasive model to predict the presence of non-alcoholic steatohepatitis in patients with non-alcoholic fatty liver disease

Autor: Rocio Lopez, Carol Hawkins, George Boon-Bee Goh, Arthur J. McCullough, Lisa Yerian, Srinivasan Dasarathy, Mangesh R. Pagadala, Naim Alkhouri, Ruth Sargent, Amer Khiyami, Achuthan Sourianarayanane, Jaividhya Dasarathy, Danny Issa, Rish K Pai

Publikováno v: Journal of Gastroenterology and Hepatology. 31:995-1000

BACKGROUND Non-alcoholic steatohepatitis (NASH) is an advanced and aggressive form of non-alcoholic fatty liver disease (NAFLD), which remains difficult to diagnose without a liver biopsy. Hyperferritinemia has increasingly been associated with the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92b55b37c63e1b7c49da2e0a8634cf19
https://doi.org/10.1111/jgh.13235

Age Impacts Ability of Aspartate–Alanine Aminotransferase Ratio to Predict Advanced Fibrosis in Nonalcoholic Fatty Liver Disease

Autor: Achuthan Sourianarayanane, Srinivasan Dasarathy, Lisa Yerian, Mangesh R. Pagadala, Rish K. Pai, Carol Hawkins, Aynur Unalp-Arida, Amer Khiyami, Arthur J. McCullough, George Boon-Bee Goh, Jaividhya Dasarathy, Ruth Sargent

Publikováno v: Digestive Diseases and Sciences. 60:1825-1831

While histological differences have been reported between pediatric and adult nonalcoholic fatty liver disease (NAFLD), potential age-related changes in serum transaminases and liver histology remain largely unexplored. Our study sought to investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a666c1a848caf61a469712e5534e36e1
https://doi.org/10.1007/s10620-015-3529-8

Iron Deficiency in Patients With Nonalcoholic Fatty Liver Disease Is Associated With Obesity, Female Gender, and Low Serum Hepcidin

Autor: Kathryn J. Fowler, Nicholas Raviele, Linda D. Ferrell, Maximillian Lee, Debra King, Melissa Paiz, Puneet Puri, Michael Fuchs, Michael S. Middleton, Tarek Hassanein, Edward Doo, Danielle Brandman, Katie Gelinas, Kim M. Cecil, Ryan M. Gill, Katie Amsden, Sherry Boyett, Archana Bhatt, Melissa Young, Mangesh R. Pagadala, Carol Sargeant, Jean P. Molleston, Mark Fishbein, Averell H. Sherker, Deana Rich, Muhammad Y. Sheikh, Kumar Sandrasegaran, Jaividhya Dasarathy, Sarah E. Barlow, Cheryl Shaw, Laura R. Carucci, Randolph K. Otto, Kimberly Pfeifer, James Tonascia, Ann O. Scheimann, Kimberlee Bernstein, Karen F. Murray, Laura A. Wilson, Amy Jones, Carol Hawkins, Evelyn K. Hsu, Laura Miriel, Miriam B. Vos, Joan Siegner, Gerald Behr, Brandon Ang, Stavra A. Xanthakos, Adina Alazraki, Elizabeth M. Brunt, Michael Torbenson, Cynthia Behling, Alexander Ko, Daniel J. Podberesky, Milana Isaacson, Peter F. Whitington, Elizabeth Kirwan, Girish Subbarao, Emily R. Perito, Saeed Mohammad, Ryan Himes, Pat Osmack, Jolene Schlosser, Patrika Tsai, Kenneth A. Kraft, Patricia Ugalde-Nicalo, Ronen Arnon, Melissa J. Contos, Bimalijit Sandhu, Mariel Boyd, Cynthia D. Guy, ünalp-Arida Aynur ünalp-Arida, Elena Reynoso, Pradeep R. Atla, Ajay Jain, Oscar W. Cummings, Shetal N. Shah, Shannon Cooney, Rajesh Krisnamurthy, Srinivasan Dasarathy, Sonia Garcia, Matthew M. Yeh, Rohit Loomba, Rohit Kohli, Ruth Sargent, Patricia Belt, Patricia R. Robuck, Ivana A. Vaughn, Mandeep Singh, Marwan Ghabril, Mohhamad S. Siddiqui, Kimberly Noble, Kara Cooper, Kimberly P. Newton, Kevin P. May, Brent A. Neuschwander-Tetri, Joel E. Lavine, Rish K. Pai, Chia Wang, Stephanie H. Abrams, Velimir A. Luketic, Kris V. Kowdley, Christopher J. N. Kigongo, Arthur J. McCullough, David E. Kleiner, Jay H. Hoofnagle, Katherine P. Yates, Sandra Arroyo, Jeanne M. Clark, Erin Corless, Melanie B. White, Dawn Piercy, Yi Ping Pan, Iliana Doycheva, Camille Langlois, Philip J. Rosenthal, Ann Quinn, James E. Nelson, Ali A. Mencin, Cynthia K. Rigsby, Stephanie Buie, Nadia Ovchinsky, Tracey Pierce, Jose Derdoy, Kathleen Lake, Cynthia Fleming, Mark L. Van Natta, Asma Siddique, Arun J. Sanyal, Janis Durelle, Phirum Nguyen, Anna Mae Diehl, Crystal Slaughter, Mazen Noureddin, Leanel Maldonado, Rebekah Garcia, Nathan M. Bass, Linda Ragozzino, Jody Mooney, Smitha Marri, Claudia Ortiz Zein, Beverly Morris, Bilal Hameed, Claude B. Sirlin, Alice L. Sternberg, Jeffrey B. Schwimmer, Melissa Wagner, David L. Coy, Michele Donithan, Naga Chalasani, Heather Patton, Susan Stewart, Dana Romo, Stephanie DeVore, Manal F. Abdelmalek, Shannon Fleck, Gilman D. Grave, Saul J. Karpen, Aliya Qayyum, Ann Klipsch, Bradley E. Aouizerat, Simon Horslen, Mustafa R. Bashir, Norah A. Terrault, Lacey Siekas, Elizabeth Byam, Sarah Ackermann, Jennifer Collins, Patricia Brandt, Ben Wolford, Raj Vuppalanchi, Rebecca Cleeton, Cathy Hurtado

Publikováno v: Clinical Gastroenterology and Hepatology. 12:1170-1178

Iron deficiency is often observed in obese individuals. The iron regulatory hormone hepcidin is regulated by iron and cytokines interleukin (IL) 6 and IL1β. We examine the relationship between obesity, circulating levels of hepcidin, and IL6 and IL1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d14740e28a36831ab61b225ccfd1347
https://doi.org/10.1016/j.cgh.2013.11.017

The development of a non-invasive model to predict the presence of non-alcoholic steatohepatitis in patients with non-alcoholic fatty liver disease

Autor: George Bb, Goh, Danny, Issa, Rocio, Lopez, Srinivasan, Dasarathy, Jaividhya, Dasarathy, Ruth, Sargent, Carol, Hawkins, Rish K, Pai, Lisa, Yerian, Amer, Khiyami, Mangesh R, Pagadala, Achuthan, Sourianarayanane, Naim, Alkhouri, Arthur J, McCullough

Publikováno v: Journal of gastroenterology and hepatology. 31(5)

Non-alcoholic steatohepatitis (NASH) is an advanced and aggressive form of non-alcoholic fatty liver disease (NAFLD), which remains difficult to diagnose without a liver biopsy. Hyperferritinemia has increasingly been associated with the presence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e9a61b646eda8877a4d22ad19e88bffc
https://pubmed.ncbi.nlm.nih.gov/26589761

Diabetes Mellitus, Insulin, Sulfonylurea and Advanced Fibrosis in Non-Alcoholic Fatty Liver Disease

Autor: George Boon-Bee Goh, Lisa Yerian, Achuthan Sourianarayanane, Carol Hawkins, Ruth Sargent, Jaividhya Dasarathy, Srinivasan Dasarathy, Amer Khiyami, Rish K. Pai, Mangesh R. Pagadala, Arthur J. McCullough, Aynur Unalp-Arida

Publikováno v: Journal of Diabetes & Metabolism.

Background & aims: Diabetes mellitus is a risk factor for advanced fibrosis in non-alcoholic fatty liver disease. However, not all non-alcoholic fatty liver disease patients with diabetes develop advanced fibrosis. We hypothesised that prescription m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28e851b7de6dad1a9a1deb5e7c652b40
https://doi.org/10.4172/2155-6156.1000410