Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Carol, Clayberger"'
Autor:
Andrew Wang, Anna-Marie Fairhurst, Kui Liu, Benjamin Wakeland, Spencer Barnes, Venkat S. Malladi, Kasthuribai Viswanathan, Carlos Arana, Igor Dozmorov, Amrita Singhar, Yong Du, Marjaan Imam, Angela Moses, Christian Chen, Ashwini Sunkavalli, Jose Casco, Dinesh Rakheja, Quan-Zhen Li, Chandra Mohan, Carol Clayberger, Edward K. Wakeland, Shaheen Khan
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Although significant progress has been achieved in elucidating the genetic architecture of systemic lupus erythematosus (SLE), identifying genes underlying the pathogenesis has been challenging. The NZM2410-derived lupus susceptibility Sle3
Externí odkaz:
https://doaj.org/article/f2cbd08d1d3449569453c8505f4d5ce9
Autor:
Shiyuan Hong, Carol Clayberger, Shouqiang Cheng, Alfred Rademaker, Alan M. Krensky, C Jie, Wei Zhang, Kruti P. Maniar
Publikováno v:
Oncogene. 35:5565-5575
High-risk strains of human papillomavirus (HPV) are the causative agents of cervical and anogenital cancers and are associated with 5% of all human cancers. Although prophylactic vaccines targeting a subset of HPV types are available, they are ineffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f667faaad5d66da1a7f7938de7dcbdd1
https://doi.org/10.1038/onc.2016.97
https://doi.org/10.1038/onc.2016.97
Autor:
Alan M. Krensky, Carol Clayberger, Seok Joo Kwon, Juan Crespo-Barreto, Dong Seok Kim, Tianhong Wang, Wei Zhang
Publikováno v:
J Immunol
Kruppel-like factor (KLF) 13 is a transcription factor that positively regulates expression of the chemokine RANTES 3–5 d after activation of T cells. In this study, we document a key role for KLF13 in the expression of IL-4 in CD4+ T cells. Gene e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446ca2ef7215d9b38a2e744349fabb07
https://doi.org/10.4049/jimmunol.1302830
https://doi.org/10.4049/jimmunol.1302830
Autor:
Carol Clayberger, Michele Pagano, Seok Joo Kwon, Wei Zhang, Byung Joon Hwang, Scott E. Millman, Alan M. Krensky, Dong Seok Kim
Publikováno v:
Blood. 120:1658-1667
RANTES (CCL5) is a chemokine implicated in many human diseases. We previously showed that the transcription factor Kruppel-like factor 13 (KLF13) controls the late (3-5 days after activation) expression of RANTES in T lymphocytes and that KLF13 itsel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a49b3488e7641a4c586accc6b8371e3
https://doi.org/10.1182/blood-2012-03-415968
https://doi.org/10.1182/blood-2012-03-415968
Autor:
David F. Stroncek, Michael W. Finn, Reena V. Saini, Christine Wilson, Valarie A. Barr, Carol Clayberger, Luciano Castiello, Alan M. Krensky, Tianhong Wang, Marianna Sabatino
Publikováno v:
The Journal of Immunology. 188:6119-6126
Granulysin is expressed as two isoforms by human cytotoxic cells: a single mRNA gives rise to 15 kDa granulysin, a portion of which is cleaved to a 9 kDa protein. Studies with recombinant 9 kDa granulysin have demonstrated its cytolytic and proinflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b82d8ad55cacc8b3b987f343f39a08
https://doi.org/10.4049/jimmunol.1200570
https://doi.org/10.4049/jimmunol.1200570
Autor:
Michael W. Finn, Carol Clayberger, Tianhong Wang, Reena V. Saini, Christine Wilson, Alan M. Krensky
Publikováno v:
The Journal of Immunology. 186:3497-3504
Granulysin is a human cytolytic molecule present in cytotoxic granules with perforin and granzymes. Recombinant 9-kDa granulysin kills a variety of microbes, including bacteria, yeast, fungi, and parasites, and induces apoptosis in tumor cells by cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8cb592786f9c88cf3f3506bff2f724
https://doi.org/10.4049/jimmunol.1003409
https://doi.org/10.4049/jimmunol.1003409
Autor:
Francesco M. Marincola, Alan M. Krensky, Carol Clayberger, Marianna Sabatino, Luciano Castiello, David F. Stroncek, Ping Jin
Publikováno v:
Cancer Immunology, Immunotherapy. 60:457-466
Ex vivo production of highly stimulator mature dendritic cells (DCs) for cellular therapy has been used to treat different pathological conditions with the aim of inducing a specific immune response. In the last decade, several protocols have been de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65c83d6d6937e4e919960a3439798db
https://doi.org/10.1007/s00262-010-0954-6
https://doi.org/10.1007/s00262-010-0954-6
Publikováno v:
Protein Expression and Purification. 75:70-74
Granulysin is an antimicrobial and proinflammatory protein expressed in activated human T cells and natural killer cells. A single mRNA produces the 15 kDa isoform which is then cleaved at the amino and carboxy termini to produce the 9 kDa isoform. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274e345d7b5f4e54d10710dd20c6d848
https://doi.org/10.1016/j.pep.2010.07.009
https://doi.org/10.1016/j.pep.2010.07.009
Autor:
Carol Clayberger
Publikováno v:
Current Opinion in Organ Transplantation. 14:30-33
Purpose of review Acute and chronic rejection are major problems in clinical transplantation. Rejection is largely mediated by natural killer (NK) and T cells that use cytolytic molecules, including perforin, granzymes, granulysin, and Fas ligand, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b95b1f2beb35a1a3d697332196eeb6f
https://doi.org/10.1097/mot.0b013e32831c8462
https://doi.org/10.1097/mot.0b013e32831c8462
Autor:
Chunhong Huang, Midori Kato-Maeda, Bo Wu, Alan M. Krensky, Philip C. Hopewell, Carol Clayberger, Charles L. Daley
Publikováno v:
Immunology Letters. 117:57-62
IL-24 is a newly described member of the IL-10 family. We previously demonstrated that PBMC from TB patients exhibited low levels of IL-24 and IFN-gamma compared to subjects with latent tuberculosis infection (LTBI). In order to investigate the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f0c3ddd854f7fe0eb89ddedad23c16
https://doi.org/10.1016/j.imlet.2007.11.018
https://doi.org/10.1016/j.imlet.2007.11.018