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Synthesis, transportability and hypoxiaselective binding of 1-beta-D-(5-Deoxy-5-fluororibofuranosyl)-2-nitroimidazole (beta-5-FAZR), a configurational isomer of the clinical hypoxia marker, FAZA

Autor: Saeed, Emami, Piyush, Kumar, Jennifer, Yang, Zbigniew, Kresolic, Robert, Paproski, Carol, Cass, Alexander Jb, McEwan, Leonard I, Wiebe

Publikováno v: Journal of pharmacypharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 10(2)

Cellular uptake of most azomycin-based radiosensitizers depends on perfusion and diffusion, rather than on active transport. In medical imaging using radioisotopically labeled azomycin nucleosides, image contrast depends on rapid diffusion from normo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5f0afc40f4ca3a04d0504cb697035ade
https://pubmed.ncbi.nlm.nih.gov/17706182

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Clinically validated benchmarking of normalisation techniques for two-colour oligonucleotide spotted microarray slides

Autor: Jennifer, Listgarten, Kathryn, Graham, Sambasivarao, Damaraju, Carol, Cass, John, Mackey, Brent, Zanke

Publikováno v: Applied bioinformatics. 2(4)

Acquisition of microarray data is prone to systematic errors. A correction, called normalisation, must be applied to the data before further analysis is performed. With many normalisation techniques published and in use, the best way of executing thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d6323bf7dd586bf6df982caef391b57e
https://pubmed.ncbi.nlm.nih.gov/15130793

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Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta

Autor: Mark Griffiths, E. V. Simon Phillips, A. Stephen Baldwin, D. James Young, Y. M. Sylvia Yao, E. Carol Cass, Fatima Abidi

Publikováno v: The Biochemical journal. 328

Mammalian equilibrative nucleoside transporters are typically divided into two classes, es and ei, based on their sensitivity or resistance respectively to inhibition by nitrobenzylthioinosine (NBMPR). Previously, we have reported the isolation of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c28217f517fc8db5a33c5eef898418
https://pubmed.ncbi.nlm.nih.gov/9396714

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