Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Carol, Brownson"'
Publikováno v:
Mechanisms of Ageing and Development. 122:1431-1445
Carnosine (beta-alanyl-L-histidine) is a physiological dipeptide which can delay ageing and rejuvenate senescent cultured human fibroblasts. Carnosine's anti-oxidant, free radical- and metal ion-scavenging activities cannot adequately explain these e
Autor:
Carol Brownson, Alan R. Hipkiss
Publikováno v:
Free Radical Biology and Medicine. 28:1564-1570
Oxidation and glycation induce formation of carbonyl (CO) groups in proteins, a characteristic of cellular aging. The dipeptide carnosine (beta-alanyl-L-histidine) is often found in long-lived mammalian tissues at relatively high concentrations (up t
Publikováno v:
Molecular Cell Biology Research Communications. 3:136-140
The LIM domain protein FHL1 (SLIM 1) transcript is preferentially expressed in postnatal skeletal muscle but almost nothing is known about its function in this tissue. In this study we have examined the expression of the FHL1 transcript at the cellul
Autor:
Alan R. Hipkiss, Carol Brownson
Publikováno v:
Biogerontology. 1:217-223
Carnosine (beta-alanyl-L-histidine) can delay senescence and provoke cellular rejuvenation in cultured human fibroblasts. The mechanisms by which such a simple molecule induces these effects is not known despite carnosine's well documented anti-oxida
Publikováno v:
Preventing Chronic Disease
Background Although the American Indian population has a disproportionately high rate of type 2 diabetes, little has been written about culturally sensitive self-management programs in this population. Context Community and clinic partners worked tog
Autor:
Hartmut Follmann, Carol Brownson
Publikováno v:
Die Naturwissenschaften. 96(11)
All known cosmic and geological conditions and laws of chemistry and thermodynamics allow that complex organic matter could have formed spontaneously on pristine planet Earth about 4,000 mya. Simple gasses and minerals on the surface and in oceans of
Autor:
Paul T. Loughna, Carol Brownson
Publikováno v:
Pflügers Archiv European Journal of Physiology. 431:990-992
Changes in carbonic anhydrase III (CAIII: normally predominant in slow type 1 fibres) and phosphoglucoisomerase (PGI: normally predominant in fast type 2 fibres) mRNAs were studied in rat slow postural soleus and fast phasic plantaris muscles which h
Publikováno v:
Biochemical and biophysical research communications. 273(1)
The actions of the insulin-like growth factors (IGF-I and IGF-II) which are essential components of skeletal muscle growth are mediated via their receptors and modulated by six binding proteins (IGFBPs). We studied IGFBP transcripts in C2C12 cell cul
Publikováno v:
Biochemical Society transactions. 26(2)
Publikováno v:
Photochemistry and photobiology. 66(5)
Exposure to solar UV radiation (UVR) leads to changes in the extracellular matrix of the dermis, which is largely composed of collagen and elastin. Collagen and elastin proteins and their corresponding mRNA were assessed in dorsal skins of hairless m