Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Carol, Beadling"'
Autor:
Matthew D. Wood, Carol Beadling, Tanaya Neff, Steve Moore, Christina A. Harrington, Lissa Baird, Christopher Corless
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract Diffuse gliomas are a heterogeneous category of primary central nervous system tumors. Due to their infiltrative growth precluding complete surgical resection, most diffuse high-grade gliomas are treated with adjuvant chemotherapy and radiat
Externí odkaz:
https://doaj.org/article/988be2512a1143a4adfbe50bdccf071b
Autor:
Allen Li, Jamie M. Keck, Swapnil Parmar, Janice Patterson, Marilyne Labrie, Allison L. Creason, Brett E. Johnson, Molly Downey, George Thomas, Carol Beadling, Laura M. Heiser, Annette Kolodzie, Alexander R. Guimaraes, Christopher L. Corless, Joe W. Gray, Gordon B. Mills, Raymond C. Bergan, Zahi I. Mitri
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-12 (2021)
Abstract Molecular heterogeneity in metastatic breast cancer presents multiple clinical challenges in accurately characterizing and treating the disease. Current diagnostic approaches offer limited ability to assess heterogeneity that exists among mu
Externí odkaz:
https://doaj.org/article/8c98543d96874c89b755cdec2ccf84d0
Publikováno v:
Human Pathology: Case Reports, Vol 25, Iss , Pp 200529- (2021)
Acinar cell carcinoma (ACC) is a rare form of pancreatic cancer that has been reported to occur in pancreatic heterotopia of the gastrointestinal tract. Molecular profiling studies of primary pancreatic ACC describe genetic alterations distinct from
Externí odkaz:
https://doaj.org/article/085cef06f17241efba31ebcb55bb30f6
Publikováno v:
Human Pathology: Case Reports, Vol 22, Iss , Pp 200434- (2020)
Since the discovery of the ETV6-NTRK3 gene fusion in infantile fibrosarcoma two decades ago, it has become an important diagnostic marker because it is found in the majority of cases. However, the development of new molecular tests, including next ge
Externí odkaz:
https://doaj.org/article/7e38d56c477443c48ea4b44692cf3cfc
Autor:
Inga-Marie Schaefer, Yuexiang Wang, Cher-wei Liang, Nacef Bahri, Anna Quattrone, Leona Doyle, Adrian Mariño-Enríquez, Alexandra Lauria, Meijun Zhu, Maria Debiec-Rychter, Susanne Grunewald, Jaclyn F. Hechtman, Armelle Dufresne, Cristina R. Antonescu, Carol Beadling, Ewa T. Sicinska, Matt van de Rijn, George D. Demetri, Marc Ladanyi, Christopher L. Corless, Michael C. Heinrich, Chandrajit P. Raut, Sebastian Bauer, Jonathan A. Fletcher
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-6 (2017)
In gastrointestinal stromal tumours early mutations in known genes are frequently followed by chromosome 14q deletion. Here the authors find mutations resulting in loss of MAX protein expression conserved between primary tumours and metastases in the
Externí odkaz:
https://doaj.org/article/f99b7b0f7dfb4944b7bbfdf9272bbf4d
Autor:
Michael C. Heinrich, Ajia Town, Carol Beadling, Diana J. Griffith, Janice Patterson, Lillian R. Klug, Alison C. Macleod
Figure S1: HMC1.2 cell line has constitutively actived NFAT2, NFAT2 and NFAT4 species; Figure S2: RT-PCR of transcripts modulated by 24 hour treatment with CSA; Figure S3: CNPIs do not modulate KIT signaling and KIT inhibitors do not affect NFAT loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e518f583acccdf8a901bb064a3d220b
https://doi.org/10.1158/1535-7163.22500676
https://doi.org/10.1158/1535-7163.22500676
Autor:
Michael C. Heinrich, Ajia Town, Carol Beadling, Diana J. Griffith, Janice Patterson, Lillian R. Klug, Alison C. Macleod
Resistant KIT mutations have hindered the development of KIT kinase inhibitors for treatment of patients with systemic mastocytosis. The goal of this research was to characterize the synergistic effects of a novel combination therapy involving inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16ae29e89fef41b4d92af10f6b06768c
https://doi.org/10.1158/1535-7163.c.6536539.v1
https://doi.org/10.1158/1535-7163.c.6536539.v1
Autor:
Michael C. Heinrich, Ajia Town, Carol Beadling, Diana J. Griffith, Janice Patterson, Lillian R. Klug, Alison C. Macleod
Figure and table legends for supplemental figures 1-4 and supplemental tables 1-3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a17edf6b5a847610c5bbe2106c2323e
https://doi.org/10.1158/1535-7163.22500679.v1
https://doi.org/10.1158/1535-7163.22500679.v1
Autor:
Michael C. Heinrich, Ujwal Shinde, Christopher Corless, Jason K. Sicklick, Oliver Harismendy, Carol Beadling, Kelly McCann, Lillian R. Klug, Ajia Town, Isaac Forquer, Jason Kent, Amber E. Bannon
Purpose: Patients who inherit a pathogenic loss-of-function genetic variant involving one of the four succinate dehydrogenase (SDH) subunit genes have up to an 86% chance of developing one or more cancers by the age of 50. If tumors are identified an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3a5a605d8ced1c183bff44000e3485
https://doi.org/10.1158/1078-0432.c.6526874
https://doi.org/10.1158/1078-0432.c.6526874
Autor:
Tomasz M. Beer, George V. Thomas, Christopher L. Corless, David Qian, Mark Garzotto, Celestia S. Higano, Tanaya Neff, Andrea Warrick, Carol Beadling, Dylan Nelson, Jeong Lim, Michael C. Heinrich, Christine M. Barnett
PDF file 41K, Appendix: Detailed Sequencing information for the solid tumor Sequenom panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbbbb533b7c6cb061e74ec3db0cb802
https://doi.org/10.1158/1078-0432.22449504.v1
https://doi.org/10.1158/1078-0432.22449504.v1