Výsledky vyhledávání - "Carnitina palmitoïl-transferasa 1"

Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth

Autor: Rut Fadó, Núria Casals, José L. Domínguez, Camilla Raiborg, Miguel Baena, Aina Roig, Dolors Serra, Marta Palomo-Guerrero, Patrick O. Helmer, Harald Stenmark, Heiko Hayen, Maria Casas, Marta Pérez-Montero

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
eLife
eLife, Vol 8 (2019)
Recercat. Dipósit de la Recerca de Catalunya
instname

Anterograde transport of late endosomes or lysosomes (LE/Lys) is crucial for proper axon growth. However, the role of energetic nutrients has been poorly explored. Malonyl-CoA is a precursor of fatty acids, and its intracellular levels highly fluctua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05a38c0ff04c8d82500ff3ab205a2c0
http://hdl.handle.net/2445/152738

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Synthesis of new Carnitine Palmitoyltransferase I inhibitors derivatives of C75

Autor: Marta López, Xavier Ariza Piquer, Dolors Serra i Cucurull, Alicia Venegas, Paula Mera Nanín, Kamil Makowski, Jordi Gómez, Laura Rodríguez

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

Carnitine Palmitoyltransferase (CPT1) is an enzyme that catalyzes the transport of fatty acids from the cytosol into the mitochondria. CPT1 inhibition in the hypothalamus increases fatty acid levels, which produces an increased expression of anorexig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe453cd61e8bc409c115200ed8f673d
http://hdl.handle.net/2445/165108

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Hypothalamic Regulation of Liver and Muscle Nutrient Partitioning by Brain-Specific Carnitine Palmitoyltransferase 1C in Male Mice

Autor: Rosalía Rodríguez-Rodríguez, Sara Ramírez, Laura Herrero, Dolors Serra, Miguel López, Patricia Seoane-Collazo, Macarena Pozo, Núria Casals

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

Carnitine palmitoyltransferase (CPT) 1C, a brain-specific protein localized in the endoplasmic reticulum of neurons, is expressed in almost all brain regions. Based on global knockout (KO) models, CPT1C has demonstrated relevance in hippocampus-depen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d288dbe1bdd135d7e2abe64f7be55e53
http://hdl.handle.net/2445/167897

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Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake

Autor: Dolors Serra, Gary D. Lopaschuk, Wendy Keung, Su Gao, Fausto G. Hegardt

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname

Carnitine palmitoyltransferase-1 (CPT-1) liver isoform, or CPT-1a, is implicated in CNS control of food intake. However, the exact brain nucleus site(s) in mediating this action of CPT-1a has not been identified. In this report, we assess the role of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74be7fb996feb57fe7d522c04ae57ce
http://hdl.handle.net/2445/54185

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Hypothalamic ceramide levels regulated by CPT1C mediate the orexigenic effect of ghrelin

Autor: Luís Martins, Carlos Dieguez, Josep Clotet, Fausto G. Hegardt, Patricia Carrasco, Jordi Jacas, Macarena Pozo, Núria Casals, Sara Ramírez, Miguel López, Dolors Serra

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Diabetes

Recent data suggest that ghrelin exerts its orexigenic action through regulation of hypothalamic AMP-activated protein kinase pathway, leading to a decline in malonyl-CoA levels and desinhibition of carnitine palmitoyltransferase 1A (CPT1A), which in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91f182046c4aaad715937192ac91cb4
http://hdl.handle.net/2445/165007

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Study of carnitine palmitoyltransferase 1A (CPT1A) in adipose tissue. Effects on obesity, inflammation and insulin resistance

Autor: Malandrino, Maria Ida

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Current lifestyle with high-energy diets and little exercise is triggering an alarming growth in obesity. Excess of adiposity is leading to severe increase in associated pathologies, such as insulin resistance, type 2 diabetes (T2DM), atherosclerosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6f5553c0f581302ad1b5229bd656fbe0
http://hdl.handle.net/10803/123966

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Papel de la carnitina palmitoiltransferasa 1A hipotalámica en el control de la ingesta

Autor: Mera Nanín, Paula

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname
Dipòsit Digital de la UB
Universidad de Barcelona

[cat]La elevada incidencia de la obesidad y las enfermedades relacionadas han convertido en una prioridad el estudio de los mecanismos destinados a controlar la ingesta y el gasto calórico. Ambos procesos están regulados por las interacciones bidir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b3a45e662e76babe1d0ef95aafa54818
http://hdl.handle.net/10803/78903

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Study of the physiological function of carnitine palmitoyltransferase 1C enzyme

Autor: Carrasco Rodríguez, Patricia

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Carnitine palmitoyl transferase 1 (CPT1) enzymes catalyze the conversion of long-chain acyl-CoA to acyl-carnitines, thus facilitating the entry of long-chain fatty acids to the mitochondria, where they undergo β-oxidation. There are three isoforms:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::669c3469d8f0dddbfb6e9a074d7b6a80
http://hdl.handle.net/10803/79172

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Molecular characterization of carnitine palmitoyltransferase 1C

Autor: Gratacòs i Batlle, Esther

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Carnitine palmitoyltransferase 1 (CPT1) catalyzes the conversion of long chain fatty acyl-CoAs into acylcarnitines, the first step in the transport of long chain fatty acids from the cytoplasm to the mitochondrial matrix, where they undergo β-oxidat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::62158504063fd964064d0ab403438c64
http://www.tdx.cat/TDX-0119111-140231

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