Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Carmine Marco Morgillo"'
Autor:
Alessandro Deplano, Jessica Karlsson, Federica Moraca, Mona Svensson, Claudia Cristiano, Carmine Marco Morgillo, Christopher J. Fowler, Roberto Russo, Bruno Catalanotti, Valentina Onnis
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 940-953 (2021)
Compounds combining dual inhibitory action against FAAH and cyclooxygenase (COX) may be potentially useful analgesics. Here, we describe a novel flurbiprofen analogue, N-(3-bromopyridin-2-yl)-2-(2-fluoro-(1,1'-biphenyl)-4-yl)propanamide (Flu-AM4). Th
Externí odkaz:
https://doaj.org/article/0b5582ac7f564cf380fe77d5fa6cd305
Autor:
Federica Zarrilli, Felice Amato, Carmine Marco Morgillo, Brunella Pinto, Giuliano Santarpia, Nicola Borbone, Stefano D’Errico, Bruno Catalanotti, Gennaro Piccialli, Giuseppe Castaldo, Giorgia Oliviero
Publikováno v:
Molecules, Vol 22, Iss 7, p 1144 (2017)
Cystic Fibrosis (CF) is one of the most common life shortening conditions in Caucasians. CF is caused by mutations in the CF Transmembrane Conductance Regulator (CFTR) gene which result in reduced or altered CFTR functionality. Several microRNAs (miR
Externí odkaz:
https://doaj.org/article/f8b80942685242c39b57075cd388456a
Autor:
Stefania Correale, Ivan de Paola, Carmine Marco Morgillo, Antonella Federico, Laura Zaccaro, Pierlorenzo Pallante, Aldo Galeone, Alfredo Fusco, Emilia Pedone, F Javier Luque, Bruno Catalanotti
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112082 (2014)
UbcH10 is a component of the Ubiquitin Conjugation Enzymes (Ubc; E2) involved in the ubiquitination cascade controlling the cell cycle progression, whereby ubiquitin, activated by E1, is transferred through E2 to the target protein with the involveme
Externí odkaz:
https://doaj.org/article/3c5deb1493154f418851aec4e72dda9f
Autor:
Carmine Marco Morgillo, Antonio Lupia, Alessandro Deplano, Luciano Pirone, Bianca Fiorillo, Emilia Pedone, F. Javier Luque, Valentina Onnis, Federica Moraca, Bruno Catalanotti
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15502
Fatty acid amide hydrolase (FAAH) plays a key role in the control of cannabinoid signaling and it represents a promising therapeutic strategy for the treatment of a wide range of diseases, including neuropathic pain and chronic inflammation. Starting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb921815fd5fe6f6575e61c27ea99f1
https://pubmed.ncbi.nlm.nih.gov/36555144
https://pubmed.ncbi.nlm.nih.gov/36555144
Autor:
Stephen Patterson, Marta Lopes Lima, Lorna MacLean, Susan Wyllie, David Horn, Lindsay B. Tulloch, Sonia Moniz, Ian H. Gilbert, Richard J. Wall, Victoriano Corpas-López, Fabio Zuccotto, Rachel Milne, Eva Rico, Carmine Marco Morgillo, Leah S. Torrie, Sandra Carvalho
Publikováno v:
Antimicrobial Agents and Chemotherapy
Phenotypic screening identified an arylsulfonamide compound with activity against Trypanosoma cruzi, the causative agent of Chagas’ disease. Comprehensive mode of action studies revealed that this compound primarily targets the T. cruzi proteasome,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f49c0c376d173d0316cb726b4e7b804
https://pubmed.ncbi.nlm.nih.gov/34606338
https://pubmed.ncbi.nlm.nih.gov/34606338
Autor:
Alessandro, Deplano, Jessica, Karlsson, Federica, Moraca, Mona, Svensson, Claudia, Cristiano, Carmine Marco, Morgillo, Christopher J, Fowler, Roberto, Russo, Bruno, Catalanotti, Valentina, Onnis
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Compounds combining dual inhibitory action against FAAH and cyclooxygenase (COX) may be potentially useful analgesics. Here, we describe a novel flurbiprofen analogue, N-(3-bromopyridin-2-yl)-2-(2-fluoro-(1,1'-biphenyl)-4-yl)propanamide (Flu-AM4). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d5ab60dd54839536f504652c4bdb65d
https://pubmed.ncbi.nlm.nih.gov/33896320
https://pubmed.ncbi.nlm.nih.gov/33896320
Autor:
Jessica Karlsson, Federica Moraca, Valentina Onnis, Alessandro Deplano, Mona Svensson, Bruno Catalanotti, Roberto Russo, Claudia Cristiano, Christopher J. Fowler, Carmine Marco Morgillo
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 940-953 (2021)
Compounds combining dual inhibitory action against FAAH and cyclooxygenase (COX) may be potentially useful analgesics. Here, we describe a novel flurbiprofen analogue, N-(3-bromopyridin-2-yl)-2-(2-fluoro-(1,1'-biphenyl)-4-yl)propanamide (Flu-AM4). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd9c57faf1465449b805b98139ba456
http://hdl.handle.net/11588/874478
http://hdl.handle.net/11588/874478
Autor:
Alessandro Deplano, Valentina Onnis, Monica Demurtas, Maria Grazia Cabiddu, Mona Svensson, Giovanni Smaldone, Ettore Novellino, Bruno Catalanotti, Emilia Pedone, Emmelie Björklund, Carmine Marco Morgillo, Sanaz Hashemian, Mariateresa Cipriano, Christopher J. Fowler, F. Javier Luque
Publikováno v:
European Journal of Medicinal Chemistry. 136:523-542
Fatty acid amide hydrolase (FAAH) has a key role in the control of the cannabinoid signaling, through the hydrolysis of the endocannabinoids anandamide and in some tissues 2-arachidonoylglycerol. FAAH inhibition represents a promising strategy to act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12274b6d7e28238d57dc17903b5ba609
https://doi.org/10.1016/j.ejmech.2017.05.033
https://doi.org/10.1016/j.ejmech.2017.05.033
Autor:
Brunella Pinto, Nicola Borbone, Giuseppe Castaldo, Carmine Marco Morgillo, Bruno Catalanotti, Giorgia Oliviero, Federica Zarrilli, Giuliano Santarpia, Gennaro Piccialli, Stefano D'Errico, Felice Amato
Publikováno v:
Molecules; Volume 22; Issue 7; Pages: 1144
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 7, p 1144 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 7, p 1144 (2017)
Cystic Fibrosis (CF) is one of the most common life shortening conditions in Caucasians. CF is caused by mutations in the CF Transmembrane Conductance Regulator (CFTR) gene which result in reduced or altered CFTR functionality. Several microRNAs (miR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c5ddd37c095b9d4cbda1285aef5a2c
Autor:
Alfredo Fusco, Ivan de Paola, Pierlorenzo Pallante, Aldo Galeone, Emilia Pedone, Bruno Catalanotti, Laura Zaccaro, Stefania Correale, Carmine Marco Morgillo, Antonella Federico, F. Javier Luque
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e112082 (2014)
Recercat. Dipósit de la Recerca de Catalunya
instname
PloS one 9 (2014): e112082. doi:10.1371/journal.pone.0112082
info:cnr-pdr/source/autori:Correale, Stefania; de Paola, Ivan; Morgillo, Carmine Marco; Federico, Antonella; Zaccaro, Laura; Pallante, Pierlorenzo; Galeone, Aldo; Fusco, Alfredo; Pedone, Emilia; Luque, F Javier; Catalanotti, Bruno/titolo:Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin./doi:10.1371%2Fjournal.pone.0112082/rivista:PloS one/anno:2014/pagina_da:e112082/pagina_a:/intervallo_pagine:e112082/volume:9
Universidad de Barcelona
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e112082 (2014)
Recercat. Dipósit de la Recerca de Catalunya
instname
PloS one 9 (2014): e112082. doi:10.1371/journal.pone.0112082
info:cnr-pdr/source/autori:Correale, Stefania; de Paola, Ivan; Morgillo, Carmine Marco; Federico, Antonella; Zaccaro, Laura; Pallante, Pierlorenzo; Galeone, Aldo; Fusco, Alfredo; Pedone, Emilia; Luque, F Javier; Catalanotti, Bruno/titolo:Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin./doi:10.1371%2Fjournal.pone.0112082/rivista:PloS one/anno:2014/pagina_da:e112082/pagina_a:/intervallo_pagine:e112082/volume:9
UbcH10 is a component of the Ubiquitin Conjugation Enzymes (Ubc; E2) involved in the ubiquitination cascade controlling the cell cycle progression, whereby ubiquitin, activated by E1, is transferred through E2 to the target protein with the involveme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4185b3435800dc8f2f88a1d6e127608d
http://hdl.handle.net/2445/123857
http://hdl.handle.net/2445/123857