MERTK in the rat trigeminal system: a potential novel target for cluster headache?

Autor: Jacob C. A. Edvinsson, Caroline Ran, Felicia Jennysdotter Olofsgård, Anna Steinberg, Lars Edvinsson, Andrea Carmine Belin

Publikováno v: The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-12 (2024)

Abstract The trigeminal system is key to the pathophysiology of migraine and cluster headache, two primary headache disorders that share many features. Recently, MER proto-oncogene tyrosine kinase (MERTK), a cell surface receptor, was strongly associ

Externí odkaz: https://doaj.org/article/84f357a143124e978b6842d78d0e84f5

Patients with cluster headache show signs of insomnia and sleep related stress: results from an actigraphy and self-assessed sleep study

Autor: Caroline Ran, Felicia Jennysdotter Olofsgård, Anna Steinberg, Christina Sjöstrand, Elisabet Waldenlind, Anna Dahlgren, Andrea Carmine Belin

Publikováno v: The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-12 (2023)

Abstract Background Cluster headache (CH) is a primary headache disorder which is characterized by circadian timing of headache attacks, usually at nighttime, in around two thirds of patients. Patients with CH often report sleep difficulties, though

Externí odkaz: https://doaj.org/article/e70786be39754ba6a4d8fafdba55333b

Establishing an online resource to facilitate global collaboration and inclusion of underrepresented populations: Experience from the MJFF Global Genetic Parkinson's Disease Project.

Autor: Eva-Juliane Vollstedt, Harutyun Madoev, Anna Aasly, Azlina Ahmad-Annuar, Bashayer Al-Mubarak, Roy N Alcalay, Victoria Alvarez, Ignacio Amorin, Grazia Annesi, David Arkadir, Soraya Bardien, Roger A Barker, Melinda Barkhuizen, A Nazli Basak, Vincenzo Bonifati, Agnita Boon, Laura Brighina, Kathrin Brockmann, Andrea Carmine Belin, Jonathan Carr, Jordi Clarimon, Mario Cornejo-Olivas, Leonor Correia Guedes, Jean-Christophe Corvol, David Crosiers, Joana Damásio, Parimal Das, Patricia de Carvalho Aguiar, Anna De Rosa, Jolanta Dorszewska, Sibel Ertan, Rosangela Ferese, Joaquim Ferreira, Emilia Gatto, Gençer Genç, Nir Giladi, Pilar Gómez-Garre, Hasmet Hanagasi, Nobutaka Hattori, Faycal Hentati, Dorota Hoffman-Zacharska, Sergey N Illarioshkin, Joseph Jankovic, Silvia Jesús, Valtteri Kaasinen, Anneke Kievit, Peter Klivenyi, Vladimir Kostic, Dariusz Koziorowski, Andrea A Kühn, Anthony E Lang, Shen-Yang Lim, Chin-Hsien Lin, Katja Lohmann, Vladana Markovic, Mika Henrik Martikainen, George Mellick, Marcelo Merello, Lukasz Milanowski, Pablo Mir, Özgür Öztop-Çakmak, Márcia Mattos Gonçalves Pimentel, Teeratorn Pulkes, Andreas Puschmann, Ekaterina Rogaeva, Esther M Sammler, Maria Skaalum Petersen, Matej Skorvanek, Mariana Spitz, Oksana Suchowersky, Ai Huey Tan, Pichet Termsarasab, Avner Thaler, Vitor Tumas, Enza Maria Valente, Bart van de Warrenburg, Caroline H Williams-Gray, Ruey-Mei Wu, Baorong Zhang, Alexander Zimprich, Justin Solle, Shalini Padmanabhan, Christine Klein

Publikováno v: PLoS ONE, Vol 18, Iss 10, p e0292180 (2023)

Parkinson's disease (PD) is the fastest-growing neurodegenerative disorder, currently affecting ~7 million people worldwide. PD is clinically and genetically heterogeneous, with at least 10% of all cases explained by a monogenic cause or strong genet

Externí odkaz: https://doaj.org/article/58585cdc8b73494895f8856cace8556b

S100B polymorphisms are associated with age of onset of Parkinson’s disease

Autor: Camilla Fardell, Anna Zettergren, Caroline Ran, Andrea Carmine Belin, Agneta Ekman, Olof Sydow, Lars Bäckman, Björn Holmberg, Nil Dizdar, Peter Söderkvist, Hans Nissbrandt

Publikováno v: BMC Medical Genetics, Vol 19, Iss 1, Pp 1-9 (2018)

Abstract Background In this study we investigated the association between SNPs in the S100B gene and Parkinson’s disease (PD) in two independent Swedish cohorts. The SNP rs9722 has previously been shown to be associated with higher S100B concentrat

Externí odkaz: https://doaj.org/article/203f3fde04324870a6d00a61f5455499

Involvement of CGRP receptor RAMP1 in cluster headache: A Swedish case-control study

Autor: Julia M Michalska, Caroline Ran, Carmen Fourier, Anna Steinberg, Christina Sjöstrand, Elisabet Waldenlind, Andrea Carmine Belin

Publikováno v: Cephalalgia Reports, Vol 2 (2019)

Background: Increased levels of the potent vasodilator calcitonin gene-related peptide (CGRP) have been found in ipsilateral jugular vein blood during the active phase of cluster headache (CH) and this is hypothesized to cause distinctive vasodilatio

Externí odkaz: https://doaj.org/article/038f3df84c2a4138b55711b25476eaea