Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes.

Autor: Zhang X; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Das T; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Chao TF; Johns Hopkins University Whiting School of Engineering, Baltiomre, MD 21218, USA., Trinh V; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Carmen-Orozco RP; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Ling JP; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Kalab P; Johns Hopkins University Whiting School of Engineering, Baltiomre, MD 21218, USA., Hayes LR; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Johns Hopkins Brain Science Institute, Baltimore, MD 21205, USA.

Publikováno v: IScience [iScience] 2024 May 24; Vol. 27 (6), pp. 110109. Date of Electronic Publication: 2024 May 24 (Print Publication: 2024).

Cell-specific regulation of gene expression using splicing-dependent frameshifting.

Autor: Ling JP; Departments of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. jling@jhu.edu.; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. jling@jhu.edu.; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, 21218, USA. jling@jhu.edu., Bygrave AM; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Santiago CP; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Carmen-Orozco RP; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Trinh VT; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Yu M; Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, 44195, USA.; Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, 44195, USA., Li Y; Departments of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Liu Y; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Bowden KD; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA., Duncan LH; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Han J; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Taneja K; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Dongmo R; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Babola TA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA., Parker P; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Jiang L; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Leavey PJ; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Smith JJ; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD, 21218, USA., Vistein R; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD, 21218, USA., Gimmen MY; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Dubner B; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Helmenstine E; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Teodorescu P; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Karantanos T; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Ghiaur G; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Kanold PO; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, 21218, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA., Bergles D; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, 21218, USA., Langmead B; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, 21218, USA.; Department of Computer Science, Johns Hopkins University, Baltimore, MD, 21218, USA., Sun S; Departments of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Nielsen KJ; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, 21218, USA.; Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD, 21218, USA., Peachey N; Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, 44195, USA.; Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, 44195, USA.; Research Service, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, 44106, USA., Singh MS; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Dalton WB; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Rajaii F; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Huganir RL; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, 21218, USA., Blackshaw S; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. sblack@jhmi.edu.; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. sblack@jhmi.edu.; Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD, 21218, USA. sblack@jhmi.edu.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. sblack@jhmi.edu.; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. sblack@jhmi.edu.

Publikováno v: Nature communications [Nat Commun] 2022 Oct 01; Vol. 13 (1), pp. 5773. Date of Electronic Publication: 2022 Oct 01.

Axonal swellings and spheroids: a new insight into the pathology of neurocysticercosis.

Autor: Mejia Maza A; Infectious Diseases Laboratory Research-LID, Faculty of Science and Philosophy, Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Perú., Carmen-Orozco RP; Infectious Diseases Laboratory Research-LID, Faculty of Science and Philosophy, Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Perú., Carter ES; Infectious Diseases Laboratory Research-LID, Faculty of Science and Philosophy, Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Perú., Dávila-Villacorta DG; Infectious Diseases Laboratory Research-LID, Faculty of Science and Philosophy, Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Perú., Castillo G; Infectious Diseases Laboratory Research-LID, Faculty of Science and Philosophy, Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Perú., Morales JD; Infectious Diseases Laboratory Research-LID, Faculty of Science and Philosophy, Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Perú., Mamani J; Faculty of Veterinary Medicine and Animal Husbandry, Universidad Peruana Cayetano Heredia, Lima, Peru., Gavídia CM; School of Veterinary Medicine, Universidad Nacional Mayor de San Marcos, Lima, Perú., Alroy J; Department of Pathology, Tufts University School of Medicine and Tufts-New England Medical Center, Boston, MA., Sterling CR; School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ., Gonzalez AE; School of Veterinary Medicine, Universidad Nacional Mayor de San Marcos, Lima, Perú., García HH; Infectious Diseases Laboratory Research-LID, Faculty of Science and Philosophy, Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Perú.; Cysticercosis Unit, Instituto Nacional de Ciencias Neurologicas, Lima, Peru., Woltjer RL; Department of Pathology, Layton Aging & Alzheimer's Disease Center, Oregon Health & Science University, Portland, OR., Verástegui MR; Infectious Diseases Laboratory Research-LID, Faculty of Science and Philosophy, Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Perú., Gilman RH; Infectious Diseases Laboratory Research-LID, Faculty of Science and Philosophy, Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Perú.; The Department of International Health, Bloomberg School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD.; Asociación Benéfica PRISMA, Lima, Perú.

Publikováno v: Brain pathology (Zurich, Switzerland) [Brain Pathol] 2019 May; Vol. 29 (3), pp. 425-436. Date of Electronic Publication: 2018 Dec 11.

In vitro model of postoncosphere development, and in vivo infection abilities of Taenia solium and Taenia saginata.

Autor: Palma S; Infectious Diseases Research Laboratory, Department of Cellular and Molecular Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru., Chile N; Infectious Diseases Research Laboratory, Department of Cellular and Molecular Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru., Carmen-Orozco RP; Infectious Diseases Research Laboratory, Department of Cellular and Molecular Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru., Trompeter G; Department of International Health, Bloomberg School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America., Fishbeck K; Department of International Health, Bloomberg School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America., Cooper V; Department of International Health, Bloomberg School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America., Rapoport L; Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Harvard University, Boston, United States of America., Bernal-Teran EG; Infectious Diseases Research Laboratory, Department of Cellular and Molecular Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru., Condori BJ; Infectious Diseases Research Laboratory, Department of Cellular and Molecular Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru., Gilman RH; Department of International Health, Bloomberg School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America., Verastegui MR; Infectious Diseases Research Laboratory, Department of Cellular and Molecular Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru.

Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Mar 14; Vol. 13 (3), pp. e0007261. Date of Electronic Publication: 2019 Mar 14 (Print Publication: 2019).