Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Carmen Wängler"'
Autor:
Benedikt Judmann, Nils F. Baier, Henning Rudolf, Güllü Davarci, Björn Wängler, Ralf Schirrmacher, Gert Fricker, Carmen Wängler
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100223- (2024)
The neuropeptide Y receptor subtype 1 (NPY(Y1)R) exhibits high expression rates on human breast cancer and is therefore an important target structure for the sensitive and specific visualization and characterization of the disease by Positron Emissio
Externí odkaz:
https://doaj.org/article/4d3a1d0a7d4c46b8be7c6dc3cbfb18a1
Autor:
Abhinay Vellala, Carolin Mogler, Florian Haag, Fabian Tollens, Henning Rudolf, Friedrich Pietsch, Carmen Wängler, Björn Wängler, Stefan O. Schoenberg, Matthias F. Froelich, Alexander Hertel
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
PurposeThis study compares phantom-based variability of extracted radiomics features from scans on a photon counting CT (PCCT) and an experimental animal PET/CT-scanner (Albira II) to investigate the potential of radiomics for translation from animal
Externí odkaz:
https://doaj.org/article/5c2c0f7b6b4f4310bb703518db27ca93
Autor:
Alexander Thiel, Alexey Kostikov, Hailey Ahn, Youstina Daoud, Jean-Paul Soucy, Stephan Blinder, Carolin Jaworski, Carmen Wängler, Björn Wängler, Freimut Juengling, Shirin A. Enger, Ralf Schirrmacher
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Background Reduced expression or impaired signalling of tropomyosin receptor kinases (Trk receptors) are found in a vast spectrum of CNS disorders. [18F]TRACK is the first PET radioligand for TrkB/C with proven in vivo brain penetration and
Externí odkaz:
https://doaj.org/article/c2a2926d0215420eb0000e3e6b42c40c
Autor:
Simon Blok, Carmen Wängler, Peter Bartenstein, Klaus Jurkschat, Ralf Schirrmacher, Simon Lindner
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Background The positron emitting isotope fluorine-18 (18F) possesses almost ideal physicochemical properties for the development of radiotracers for diagnostic molecular imaging employing positron emission tomography (PET). 18F in its nucleo
Externí odkaz:
https://doaj.org/article/3bf72b1da7384c5f99d2d68736359122
Autor:
Marie Prochiner, Benedikt Judmann, Alina Ruder, Björn Wängler, Ralf Schirrmacher, Carmen Wängler
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1280 (2024)
Background: Affibody molecules represent a class of highly specific binders of particular interest for the development of highly affine target-specific radiopharmaceuticals. Their chemical synthesis is, however, intricate due to their considerable le
Externí odkaz:
https://doaj.org/article/99280944783a41a89c6e96d3c0c160c9
Autor:
Carmen Wängler, Leonie Beyer, Peter Bartenstein, Björn Wängler, Ralf Schirrmacher, Simon Lindner
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 7, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/1f412ef2ab4744d3aca800146c8151d2
Autor:
Güllü Davarci, Carmen Wängler, Klaus Eberhardt, Christopher Geppert, Ralf Schirrmacher, Robert Freudenberg, Marc Pretze, Björn Wängler
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1670 (2023)
This paper reports on the development of stable tumor-specific gold nanoparticles (AuNPs) activated by neutron irradiation as a therapeutic option for the treatment of cancer with high tumor angiogenesis. The AuNPs were designed with different mono-
Externí odkaz:
https://doaj.org/article/0f534cf3d7e347a4b9fd0de853dd5e97
Autor:
Ralf S. Eschbach, Markus Hofmann, Lukas Späth, Gabriel T. Sheikh, Astrid Delker, Simon Lindner, Klaus Jurkschat, Carmen Wängler, Björn Wängler, Ralf Schirrmacher, Reinhold Tiling, Matthias Brendel, Vera Wenter, Franziska J. Dekorsy, Mathias J. Zacherl, Andrei Todica, Harun Ilhan, Freba Grawe, Clemens C. Cyran, Marcus Unterrainer, Johannes Rübenthaler, Thomas Knösel, Tanja Paul, Stefan Boeck, Christoph Benedikt Westphalen, Christine Spitzweg, Christoph J. Auernhammer, Peter Bartenstein, Lena M. Unterrainer, Leonie Beyer
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeSomatostatin analogues (SSA) are frequently used in the treatment of neuroendocrine tumours. Recently, [18F]SiTATE entered the field of somatostatin receptor (SSR) positron emission tomography (PET)/computed tomography (CT) imaging. The purpos
Externí odkaz:
https://doaj.org/article/3d44f66487cd4f03ae7b9ac67d9471d4
Autor:
Justin J. Bailey, Melinda Wuest, Tamara Bojovic, Travis Kronemann, Carmen Wängler, Björn Wängler, Frank Wuest, Ralf Schirrmacher
Publikováno v:
ACS Omega, Vol 6, Iss 33, Pp 21741-21754 (2021)
Externí odkaz:
https://doaj.org/article/821982e14bc64188abba65b2e16696f9
Autor:
Marc Pretze, Laura Reffert, Steffen Diehl, Stefan O. Schönberg, Carmen Wängler, Peter Hohenberger, Björn Wängler
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-13 (2021)
Abstract Background [68Ga]Ga-NeoB is a novel DOTA-coupled Gastrin Releasing Peptide Receptor (GRPR) antagonist with high affinity for GRPR and good in vivo stability. This study aimed at (1) the translation of preclinical results to the clinics and e
Externí odkaz:
https://doaj.org/article/565810819d3d408980e85f7f52a44c84