Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Carmen Vanessa Ortiz-Ruiz"'
Autor:
Carmen Vanessa Ortiz-Ruiz, Francisco García-Cánovas, Antonio Garcia-Jimenez, José Tudela, Jose Antonio Teruel-Puche, Jose Berna
Publikováno v:
Reaction Kinetics, Mechanisms and Catalysis. 120:1-13
When the action of tyrosinase on l-dopa in the presence of 3-aminoacetophenone is studied, inhibition or activation is observed depending on the concentration of substrate. These opposing effects are due to non-enzymatic reactions: when tyrosinase ac
Autor:
María Llanos Amo-Saus, Manuela García-Moreno, Julio Escribano, Maria D. Masia, Ramón Varón, Carmen Vanessa Ortiz-Ruiz, Milagros Molina-Alarcón, Francisco García-Sevilla
Publikováno v:
Journal of Mathematical Chemistry. 54:1952-1972
In this paper we analyse the transient phase, i.e., the time course, of the fractional modification of monocyclic enzyme cascades with a more complete realistic definition for fractional modification as the fraction of the original enzyme converted i
Autor:
Jose Antonio Teruel-Puche, Francisco García-Cánovas, José Tudela, Jose Berna, Antonio Garcia-Jimenez, Carmen Vanessa Ortiz-Ruiz
Publikováno v:
IUBMB Life. 68:663-672
4-n-Butylresorcinol (BR) is considered the most potent inhibitor of tyrosinase, which is why it is used in cosmetics as a depigmenting agent. However, this work demonstrates that BR is a substrate of this enzyme. The Em (met-tyrosinase) form is not a
Autor:
Jose Luis Muñoz-Muñoz, Francisco García-Cánovas, Miguel A. Maria-Solano, Jose Antonio Teruel-Puche, Carmen Vanessa Ortiz-Ruiz, Jose Berna, Pedro Antonio García-Ruiz
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 125:6-15
The pH has a great physiological effect on the catalysis of tyrosinase because protons can act as competitive-type inhibitors. In this work, a reaction mechanism is proposed whereby only the protonation of the free forms Em (met-tyrosinase) and Eox (
Autor:
Francisco García-Cánovas, Carmen Vanessa Ortiz-Ruiz, Manuel Ballesta de los Santos, Jose Berna, José Tudela, Pedro Antonio García-Ruiz, Jose Fenoll
Publikováno v:
IUBMB Life. 67:828-836
Oxyresveratrol is a stilbenoid described as a powerful inhibitor of tyrosinase and proposed as skin-whitening and anti-browning agent. However, the enzyme is capable of acting on it, considering it as a substrate, as it has been proved in the case of
Autor:
Ramón Varón, José Tudela, Carmen Vanessa Ortiz-Ruiz, Maria del Mar Garcia-Molina, Francisco García-Cánovas, Virginia Tomás, Miguel A. Maria-Solano
Publikováno v:
IUBMB Life. 67:757-767
The development of effective tyrosinase inhibitors has become increasingly important in the cosmetic, medicinal, and agricultural industries for application as antibrowning and depigmenting agents. The kinetic mechanisms of action of tyrosinase on mo
Autor:
Carmen Vanessa Ortiz-Ruiz, Jose Tudela Serrano, Virginia Tomas-Martinez, Francisco García-Cánovas, Maria del Mar Garcia-Molina
Publikováno v:
Journal of Agricultural and Food Chemistry. 63:2162-2171
Many phenolic compounds have been described in the scientific literature as inhibitors of tyrosinase. In this work a test is proposed that allows us to distinguish whether a molecule is an enzyme inhibitor or substrate. The test has several stages. F
Autor:
Antonio, Garcia-Jimenez, Jose Antonio, Teruel-Puche, Carmen Vanessa, Ortiz-Ruiz, Jose, Berna, Jose, Tudela, Francisco, Garcia-Canovas
Publikováno v:
IUBMB life. 68(8)
4-n-Butylresorcinol (BR) is considered the most potent inhibitor of tyrosinase, which is why it is used in cosmetics as a depigmenting agent. However, this work demonstrates that BR is a substrate of this enzyme. The Em (met-tyrosinase) form is not a
Publikováno v:
Journal of dermatological science. 82(2)
Background Tyrosinase is an enzyme involved in the first steps of the melanogenesis process. It catalyzes the hydroxylation of monophenols to o-diphenols and the oxidation of the latter to o-quinones. Ellagic acid (EA) is a phenolic compound which ha
Autor:
Carmen Vanessa, Ortiz-Ruiz, Miguel Angel, Maria-Solano, Maria Del Mar, Garcia-Molina, Ramon, Varon, Jose, Tudela, Virginia, Tomas, Francisco, Garcia-Canovas
Publikováno v:
IUBMB life. 67(10)
The development of effective tyrosinase inhibitors has become increasingly important in the cosmetic, medicinal, and agricultural industries for application as antibrowning and depigmenting agents. The kinetic mechanisms of action of tyrosinase on mo