Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Carmen R. Wood"'
Autor:
Katherine L. O’Shaughnessy, Kiersten S. Bell, Aubrey L. Sasser, Mary E. Gilbert, Cal Riutta, Jermaine L. Ford, James McCord, Carmen R. Wood
Publikováno v:
Environment International, Vol 190, Iss , Pp 108838- (2024)
Known as “forever chemicals”, per- and polyfluoroalkyl substances (PFAS) are synthetic compounds used in consumer goods but pose significant public health concerns, including disruption of the thyroid system. As thyroid hormones (THs) are require
Externí odkaz:
https://doaj.org/article/bb4198e0f99f4d2dbdb1a2cb1164bfed
Publikováno v:
PPAR Research, Vol 2010 (2010)
Externí odkaz:
https://doaj.org/article/1a0ccffb0f864cf0b17479260acdc46f
Publikováno v:
PPAR Research, Vol 2010 (2010)
Peroxisome proliferator-activated receptors (PPARs) regulate lipid and glucose homeostasis, are targets of pharmaceuticals, and are also activated by environmental contaminants. Almost nothing is known about expression of PPARs during human fetal dev
Externí odkaz:
https://doaj.org/article/28c4f918c680448b916749ed5cece20a
Autor:
Mary E. Gilbert, Anne Marie Vinggaard, Louise Ramhøj, Terje Svingen, Ulla Hass, Karen Mandrup, Diana Usai, Carmen R. Wood, Marta Axelstad
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Ramhøj, L, Hass, U, Gilbert, M E, Wood, C, Svingen, T, Usai, D, Vinggaard, A M, Mandrup, K & Axelstad Petersen, M 2020, ' Evaluating thyroid hormone disruption : investigations of long-term neurodevelopmental effects in rats after perinatal exposure to perfluorohexane sulfonate (PFHxS) ', Scientific Reports, vol. 10, no. 1, 2672 . https://doi.org/10.1038/s41598-020-59354-z
Scientific Reports
Ramhøj, L, Hass, U, Gilbert, M E, Wood, C, Svingen, T, Usai, D, Vinggaard, A M, Mandrup, K & Axelstad Petersen, M 2020, ' Evaluating thyroid hormone disruption : investigations of long-term neurodevelopmental effects in rats after perinatal exposure to perfluorohexane sulfonate (PFHxS) ', Scientific Reports, vol. 10, no. 1, 2672 . https://doi.org/10.1038/s41598-020-59354-z
Thyroid hormones are critical for mammalian brain development. Thus, chemicals that can affect thyroid hormone signaling during pregnancy are of great concern. Perfluorohexane sulfonate (PFHxS) is a widespread environmental contaminant found in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2a8e6e6debc5596939c7f5b4ab7894
http://link.springer.com/article/10.1038/s41598-020-59354-z
http://link.springer.com/article/10.1038/s41598-020-59354-z
Autor:
Cal Riutta, Susan E Thomas, Mary E. Gilbert, Alicia Smith, Iman Hassan, Michelle G. Hotchkiss, Richard L Ford, Katherine L O'Shaughnessy, Carmen R. Wood, Wendy O Oshiro, Jermaine Ford
Publikováno v:
Toxicol Sci
Many xenobiotics are identified as potential thyroid disruptors due to their action to reduce circulating levels of thyroid hormone, most notably thyroxine (T4). Developmental neurotoxicity is a primary concern for thyroid disrupting chemicals yet co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5099308b2d6aeb943444318acdfc93
https://europepmc.org/articles/PMC9038230/
https://europepmc.org/articles/PMC9038230/
Autor:
Mary E Gilbert, Katherine L O’Shaughnessy, Susan E Thomas, Cal Riutta, Carmen R Wood, Alicia Smith, Wendy O Oshiro, Richard L Ford, Michelle Gatien Hotchkiss, Iman Hassan, Jermaine L Ford
Publikováno v:
Toxicological Sciences. 187:186-186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11c21837a9aeb0c61713a80787a1bd0e
https://doi.org/10.1093/toxsci/kfac026
https://doi.org/10.1093/toxsci/kfac026
Autor:
Carmen R. Wood, Sierra D Moorefield, Carrie M. Becker, Cynthia J. Wolf, David G. Belair, Barbara D. Abbott
Publikováno v:
Toxicological Sciences.
Embryologic development involves cell differentiation and organization events that are unique to each tissue and organ and are susceptible to developmental toxicants. Animal models are the gold standard for identifying putative teratogens, but the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3548350fdebcbe27fffed0fe1a963bd5
https://doi.org/10.1093/toxsci/kfy207
https://doi.org/10.1093/toxsci/kfy207
Autor:
Richard L Ford, Katherine L O'Shaughnessy, Sigmund J. Degitz, Patricia A. Kosian, Mary E. Gilbert, Michelle G. Hotchkiss, Carmen R. Wood
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 166(1)
Adverse neurodevelopmental consequences remain a primary concern when evaluating the effects of thyroid hormone (TH) disrupting chemicals. Though the developing brain is a known target of TH insufficiency, the relationship between THs in the serum an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3bdeeff62467d72b3deadeaaaaff94c
https://pubmed.ncbi.nlm.nih.gov/30085217
https://pubmed.ncbi.nlm.nih.gov/30085217
Autor:
Elizabeth McRae Whitley, G. S. Travlos, Donna Hill, Carmen R. Wood, D. L. Diggs, I. Chorus, Johnsie R. Lang, Thanh-Thao Le, J. E. Schmid, Neil Chernoff, R. E. Wilson, H. Huang, Debra King
Publikováno v:
Journal of toxicology and environmental health. Part A. 81(13)
Cylindrospermopsin (CYN) is a toxin associated with numerous species of freshwater cyanobacteria throughout the world. It is postulated to have caused an episode of serious illnesses in Australia through treated drinking water, as well as lethal effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5f6c843bd282da612953a4d3b3da81
https://pubmed.ncbi.nlm.nih.gov/29693504
https://pubmed.ncbi.nlm.nih.gov/29693504
Autor:
Andrew B. Lindstrom, R. Daniel Zehr, Kaberi P. Das, Brian E. Grey, Carmen R. Wood, Christopher Lau, Mitchell B. Rosen, Katoria Tatum-Gibbs, Mark J. Strynar
Publikováno v:
Reproductive Toxicology. 51:133-144
Perfluorononanoic acid (PFNA) is a ubiquitous and persistent environmental contaminant. Although its levels in the environment and in humans are lower than those of perfluorooctane sulfonate (PFOS) or perfluorooctanoic acid (PFOA), a steady trend of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5d3209ad04e4fa557ccfda619de91b
https://doi.org/10.1016/j.reprotox.2014.12.012
https://doi.org/10.1016/j.reprotox.2014.12.012