Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Carmen Punzón"'
Autor:
Sara Francisco, Jean-Marc Billod, Javier Merino, Carmen Punzón, Alicia Gallego, Alicia Arranz, Sonsoles Martin-Santamaria, Manuel Fresno
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
The Toll-like receptor 4 (TLR4)/myeloid differentiation protein-2 (MD-2) complex is considered the major receptor of the innate immune system to recognize lipopolysaccharides (LPSs). However, some atypical LPSs with different lipid A and core sacchar
Externí odkaz:
https://doaj.org/article/f30137138c20417b8da847b71b1bb3ba
Autor:
Natalia Cuesta, Sonia Fernández-Veledo, Carmen Punzón, Cristóbal Moreno, Beatriz Barrocal, Vinatha Sreeramkumar, Manuel Desco, Manuel Fresno
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15682 (2022)
Understanding the signaling cascades that govern adipocyte metabolism and differentiation is necessary for the development of therapies for obesity. Toll-like receptors (TLRs) are key mediators in adipogenesis, but their specific role is not complete
Externí odkaz:
https://doaj.org/article/ce0e36e185f44b8cb91782d02bd2ca2d
Autor:
Lucía Pérez-Regidor, Joan Guzmán-Caldentey, Nils Oberhauser, Carmen Punzón, Balázs Balogh, José R. Pedro, Eva Falomir, Alessandra Nurisso, Péter Mátyus, J. Carlos Menéndez, Belén de Andrés, Manuel Fresno, Sonsoles Martín-Santamaría
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2326 (2022)
The innate immunity toll-like receptor 4 (TLR4) system is a receptor of paramount importance as a therapeutic target. Virtual screening following a “computer-aided drug repurposing” approach was applied to the discovery of novel TLR4 modulators w
Externí odkaz:
https://doaj.org/article/0f1178007a05470795f7fc9e89be0e3d
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Toll-like receptors (TLRs) play a crucial role in the recognition of pathogen-derived components as a first line of defense against infections. It has been suggested that depending on the nature of the pathogens, TLRs activation induce a distinct cyt
Externí odkaz:
https://doaj.org/article/2bf40a59ba9a43eaba3fc44fe71de666
Autor:
Raquel Álvarez-Velilla, Maria Del Camino Gutiérrez-Corbo, Carmen Punzón, Maria Yolanda Pérez-Pertejo, Rafael Balaña-Fouce, Manuel Fresno, Rosa María Reguera
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007133 (2019)
BACKGROUND:Visceral leishmaniasis is a neglected parasitic disease with no vaccine available and its pharmacological treatment is reduced to a limited number of unsafe drugs. The scarce readiness of new antileishmanial drugs is even more alarming whe
Externí odkaz:
https://doaj.org/article/9b22059eb700424ea46e4480c3bcf387
Autor:
Estefanía Calvo-Álvarez, Kostantinos Stamatakis, Carmen Punzón, Raquel Álvarez-Velilla, Ana Tejería, José Miguel Escudero-Martínez, Yolanda Pérez-Pertejo, Manuel Fresno, Rafael Balaña-Fouce, Rosa M Reguera
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003666 (2015)
BACKGROUND:Visceral leishmaniasis (VL) is hypoendemic in the Mediterranean region, where it is caused by the protozoan Leishmania infantum. An effective vaccine for humans is not yet available and the severe side-effects of the drugs in clinical use,
Externí odkaz:
https://doaj.org/article/2d5d420e6cb7481b8cae71aaac0a7e0c
Autor:
Jossela Calderón, Elena Maganto-Garcia, Carmen Punzón, Javier Carrión, Cox Terhorst, Manuel Fresno
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002799 (2012)
Trypanosoma cruzi, the protozoan parasite responsible for Chagas' disease, causes severe myocarditis often resulting in death. Here, we report that Slamf1-/- mice, which lack the hematopoietic cell surface receptor Slamf1, are completely protected fr
Externí odkaz:
https://doaj.org/article/705cb3dd0c1d4d8281a26754bcf107d9
Autor:
Estefania Calvo-Álvarez, Nestor Adrian Guerrero, Raquel Alvarez-Velilla, Christopher Fernández Prada, Jose María Requena, Carmen Punzón, Miguel Ángel Llamas, Francisco J Arévalo, Luis Rivas, Manuel Fresno, Yolanda Pérez-Pertejo, Rafael Balaña-Fouce, Rosa M Reguera
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 11, p e1927 (2012)
BACKGROUND: Leishmania major cutaneous leishmaniasis is an infectious zoonotic disease. It is produced by a digenetic parasite, which resides in the phagolysosomal compartment of different mammalian macrophage populations. There is an urgent need to
Externí odkaz:
https://doaj.org/article/c614392264324ca9a55b632c47e15a0d
Autor:
Francisco Sánchez-Madrid, Julián Aragonés, María Laura Saiz, Jesús Vázquez, Hortensia de la Fuente, Esteban Daudén, Inmaculada Jorge, Danay Cibrian, Manuel Fresno, Javier Fraga-Fernández, Marta Ramírez-Huesca, Raquel Castillo-González, Miguel Vicente-Manzanares, Nieves Fernández-Gallego, Carmen Punzón
Publikováno v:
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Biblos-e Archivo. Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Biblos-e Archivo. Repositorio Institucional de la UAM
[Background]: Psoriasis is a frequent inflammatory skin disease that is mainly mediated by IL-23, IL-1β, and IL-17 cytokines. Although psoriasis is a hyperproliferative skin disorder, the possible role of amino acid transporters has remained unexplo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e914ac7a7d78ef77659df8f89d79ab66
http://hdl.handle.net/10261/223074
http://hdl.handle.net/10261/223074
Autor:
Sonsoles Yañez-Diaz, Fernando Rivera, Hector Teran-Navarro, Javier Gómez-Román, Isabel García, Claudia González-Rico, Carmen Alvarez-Dominguez, Manuel Fresno, Soledad Penadés, Javier Freire, Marco Marradi, David Salcines-Cuevas, Carmen Punzón, Elisabet Frande-Cabanes, Ana Castañeda-Sampedro, Ricardo Calderon-Gonzalez, M. Carmen Fariñas, José María Marimón, Mirian Alkorta-Gurrutxaga, Aida San Nicolas-Gomez
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Oncotarget. 2017 Jul 20;8(33):53916-53934
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Oncotarget. 2017 Jul 20;8(33):53916-53934
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Clinical cases of neonatal listeriosis are associated with brain disease and fetal loss due to complications in early or late pregnancy, which suggests that microglial function is altered. This is believed to be the first study to link microglial apo