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pro vyhledávání: '"Carmen Martin-Alonso"'
Akademický článek
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Publikováno v:
ACS Omega. 7:24292-24301
Analyzing the activity of proteases and their substrates is critical to defining the biological functions of these enzymes and to designing new diagnostics and therapeutics that target protease dysregulation in disease. While a wide range of database
Autor:
Shervin Tabrizi, Carmen Martin-Alonso, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Zhenyi An, Sahil Patel, Sergio Rodriguez-Aponte, Christopher A. Naranjo, Shih-Ting Wang, Douglas Shea, Todd R. Golub, Sangeeta N. Bhatia, Viktor Adalsteinsson, J. Christopher Love
Publikováno v:
bioRxiv
Blood-based, or “liquid,” biopsies enable minimally invasive diagnostics but have limits on sensitivity due to scarce cell-free DNA (cfDNA). Improvements to sensitivity have primarily relied on enhancing sequencing technologyex vivo. Here, we sou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f801620377ed2460cada89da0da0f1
https://doi.org/10.1101/2023.01.13.523947
https://doi.org/10.1101/2023.01.13.523947
Autor:
Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Timothy Blewett, Sahil Patel, Zhenyi An, Sainetra Sridhar, Ahmet Bekdemir, Douglas Shea, Ava P. Amini, Shih-Ting Wang, Jesse Kirkpatrick, Justin Rhoades, Todd R. Golub, J. Christopher Love, Viktor A. Adalsteinsson, Sangeeta N. Bhatia
Publikováno v:
bioRxiv
Liquid biopsies are enabling minimally invasive monitoring and molecular profiling of diseases across medicine, but their sensitivity remains limited by the scarcity of cell-free DNA (cfDNA) in blood. Here, we report an intravenous priming agent that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c820d25086601d81af5b242564adf344
https://doi.org/10.1101/2023.01.13.524003
https://doi.org/10.1101/2023.01.13.524003
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Shervin Tabrizi, Carmen Martin-Alonso, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Zhenyi An, Sahil Patel, Sergio Rodriguez-Aponte, Christopher Naranjo, Douglas Shea, Todd Golub, Sangeeta N. Bhatia, Viktor A. Adalsteinsson, J. Christopher Love
Publikováno v:
Cancer Research. 83:3371-3371
Liquid biopsies using cell-free DNA (cfDNA) enable non-invasive detection and characterization of disease. Advances in sequencing methods have significantly improved the performance of liquid biopsies. Yet, despite these advances, sensitivity remains
Autor:
Guinevere G. Connelly, Orville O. Kirkland, Seven Bohannon, Daniel C. Lim, Robert M. Wilson, Edward J. Richards, Dousabel M. Tay, Hyuk Jee, Riley D. Hellinger, Ngoc K. Hoang, Liang Hao, Arnav Chhabra, Carmen Martin-Alonso, Edward K.W. Tan, Angela N. Koehler, Michael B. Yaffe, Wendy B. London, Pui Y. Lee, Florian Krammer, Robert C. Bohannon, Sangeeta N. Bhatia, Hadley D. Sikes, Hojun Li
Publikováno v:
Cell reports methods. 2(8)
Neutralizing antibody (NAb) titer is a key biomarker of protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but point-of-care methods for assessing NAb titer are not widely available. Here, we present a lateral
Autor:
Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Ahmet Bekdemir Bekdemir, Sahil Patel, Zhenyi An, Timothy Blewett, Sainetra Sridhar, Douglas Shea, Ava Amini, Jesse D. Kirkpatrick, Jin Bae, Eugenia Roberts, Ruolin Liu, Justin Rhoades, Todd Golub, J. Christopher Love, Viktor A. Adalsteinsson, Sangeeta N. Bhatia
Publikováno v:
Cancer Prevention Research. 16:PR007-PR007
Liquid biopsy measurements, such as analysis of circulating tumor DNA (ctDNA) shed by cancer cells, have garnered significant attention for their potential to empower the field of precision oncology. Given that ctDNA tests could enable minimally inva
Autor:
Peter M. K. Westcott, Tuomas Tammela, Ava P. Soleimany, Heather E. Fleming, Andrew Warren, Justin C. Voog, Sangeeta N. Bhatia, Carmen Martin-Alonso, Jesse D. Kirkpatrick, Tyler Jacks
Publikováno v:
Sci Transl Med
Lung cancer is the leading cause of cancer-related death, and patients most commonly present with incurable advanced-stage disease. U.S. national guidelines recommend screening for high-risk patients with low-dose computed tomography, but this approa
Autor:
Carmen Herencia, Juan Miguel Diaz-Tocados, Lidia Jurado, Addy Montes de Oca, Maria Encarnación Rodríguez-Ortiz, Carmen Martín-Alonso, Julio M Martínez-Moreno, Noemi Vergara, Mariano Rodríguez, Yolanda Almadén, Juan R Muñoz-Castañeda
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156788 (2016)
Periodontitis is a complex pathology characterized by the loss of alveolar bone. The causes and the mechanisms that promote this bone resorption still remain unknown. The knowledge of the critical regulators involved in the alteration of alveolar bon
Externí odkaz:
https://doaj.org/article/c62474a98a3d43048781fef9c528f37d