Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Carmen Marín-Bañasco"'
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Akademický článek
The presence and suppressive activity of myeloid-derived suppressor cells are potentiated after interferon-β treatment in a murine model of multiple sclerosis
Autor: Carolina Melero-Jerez, Margarita Suardíaz, Rafael Lebrón-Galán, Carmen Marín-Bañasco, Begoña Oliver-Martos, Isabel Machín-Díaz, Óscar Fernández, Fernando de Castro, Diego Clemente
Publikováno v: Neurobiology of Disease, Vol 127, Iss , Pp 13-31 (2019)
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the human central nervous system (CNS), mainly affecting young adults. Among the immunomodulatory disease modifying treatments approved up to date to treat MS, IFN-β remains to be one
Externí odkaz: https://doaj.org/article/bdc793728b8c483382a1b841c1b6bc71
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2
The presence and suppressive activity of myeloid-derived suppressor cells are potentiated after interferon-β treatment in a murine model of multiple sclerosis
Autor: Rafael Lebrón-Galán, Fernando de Castro, Margarita Suardíaz, Oscar Fernandez, Carolina Melero-Jerez, Isabel Machín-Díaz, Begoña Oliver-Martos, Diego Clemente, Carmen Marín-Bañasco
Publikováno v: Neurobiology of Disease, Vol 127, Iss, Pp 13-31 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
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Multiple sclerosis (MS) is an autoimmune demyelinating disease of the human central nervous system (CNS), mainly affecting young adults. Among the immunomodulatory disease modifying treatments approved up to date to treat MS, IFN-β remains to be one
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6716f9286d9a214301e9a3b39e1226
http://www.sciencedirect.com/science/article/pii/S0969996119300439
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3
Gene therapy with mesenchymal stem cells expressing IFN-ß ameliorates neuroinflammation in experimental models of multiple sclerosis
Autor: Karim Benabdellah, Carmen Marín-Bañasco, Begoña Oliver, F. de Castro, Isaac Hurtado-Guerrero, M.J. Pinto-Medel, Diego Clemente, Laura Leyva, Margarita Suardíaz, Oscar Fernández, F Martin, Carolina Melero-Jerez
Publikováno v: British Journal of Pharmacology. 174:238-253
Background and Purpose Recombinant IFNs is one of the first line treatments in multiple sclerosis (MS), despite its lack of efficiency in some patients. In this context, mesenchymal stem cells (MSCs) represent a promising therapeutic alternative due
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9fdecc786f0149b144ec3fd1f9c9826
https://doi.org/10.1111/bph.13674
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4
Recombinant soluble IFN receptor (sIFNAR2) exhibits intrinsic therapeutic efficacy in a murine model of Multiple Sclerosis
Autor: Isaac Hurtado-Guerrero, José Pavia, Begoña Oliver, Margarita Suardíaz, Diego Clemente, Oscar Fernández, Laura Leyva, T. Orpez, M.J. Pinto-Medel, Carmen Marín-Bañasco, F. de Castro
Publikováno v: Neuropharmacology. 110:480-492
Endogenous interferon beta (IFNβ) is an important cytokine involved in several chronic inflammatory diseases, such as Multiple Sclerosis (MS). In spite of the numerous therapeutic approaches available for MS patients, the administration of recombina
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea418e0477f13db7cd835e4ecbfdc47
https://doi.org/10.1016/j.neuropharm.2016.07.026
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The CD4+ T-cell subset lacking expression of the CD28 costimulatory molecule is expanded and shows a higher activation state in multiple sclerosis
Autor: María Jesús Pinto-Medel, Begoña Oliver-Martos, Carmen Marín-Bañasco, Carlos Arnáiz-Urrutia, Oscar Fernandez, Laura Leyva, G. Luque, Juan Antonio García-León, Teresa Órpez, Carlos López-Gómez
Publikováno v: Journal of Neuroimmunology. 243:1-11
Multiple sclerosis (MS) is a chronic debilitating disease, in which T-cells are considered to play a pivotal role. CD28 is the quintessential costimulatory molecule on T-cells and its expression declines progressively with repeated stimulations, lead
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a679bf0c324df2ec0e5d7f43c864cc9
https://doi.org/10.1016/j.jneuroim.2011.11.008
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6
Mesenchymal properties of SJL mice-stem cells and their efficacy as autologous therapy in a relapsing–remitting multiple sclerosis model
Autor: Rafael Maldonado Sánchez, Carmen Marín-Bañasco, Margarita Suardíaz García, Issac Hurtado Guerrero, Guillermo Estivill-Torrús, Laura Leyva Fernández, Oscar Fernández
Publikováno v: Stem Cell Research & Therapy
Introduction Mesenchymal stem cells (MSCs) are a multipotent population of adult stem cells, which may represent a promising therapeutic approach for neurological autoimmune diseases such as multiple sclerosis. The mouse is the most used species for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c25f5df50dca7c27ee1a58f6df2055c
https://doi.org/10.1186/scrt524
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7
Killer-cell immunoglobulin-like receptor expression on lymphocyte subsets in multiple sclerosis patients treated with interferon-β: evaluation as biomarkers for clinical response
Autor: Carlos López-Gómez, Oscar Fernandez, Juan Antonio García-León, Teresa Órpez-Zafra, Begoña Oliver-Martos, Virginia Reyes-Garrido, Laura Leyva, Carmen Marín-Bañasco
Publikováno v: CNS drugs. 28(6)
Both the adaptative and the innate immune systems interplay in multiple sclerosis (MS) pathogeny. Killer-cell immunoglobulin-like receptors (KIRs) are key regulators of the immune response, with activating and inhibitory isoforms.In this study we ana
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bdc4c8d428dfd3881bf0cf1bf891e7a
https://pubmed.ncbi.nlm.nih.gov/24599774
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8
Killer cell immunoglobulin-like receptor genes in Spanish multiple sclerosis patients
Autor: Begoña Oliver-Martos, Carmen Marín-Bañasco, María Jesús Pinto-Medel, Rafael Maldonado-Sanchez, Isidro Prat-Arrojo, Lucía García-Trujillo, Juan Antonio García-León, Óscar Fernández-Fernández, Laura Leyva-Fernández, Carlos López-Gómez, Margarita Suardíaz-García
Publikováno v: Molecular immunology. 48(15-16)
Killer cell immunoglobulin-like receptors (KIRs) are regulators of cytolytic activity of natural killer and certain T cells through interactions with human leukocyte antigen (HLA) class I ligands. KIRs have been shown to contribute to the pathogenesi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5785d2ad14fdf7ec9895316f3fcb4114
https://pubmed.ncbi.nlm.nih.gov/21665278
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