Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Carmen M Warren"'
Autor:
Elizabeth Allen, Pascal Miéville, Carmen M. Warren, Sadegh Saghafinia, Leanne Li, Mei-Wen Peng, Douglas Hanahan
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1144-1160 (2016)
Therapeutic targeting of tumor angiogenesis with VEGF inhibitors results in demonstrable, but transitory efficacy in certain human tumors and mouse models of cancer, limited by unconventional forms of adaptive/evasive resistance. In one such mouse mo
Externí odkaz:
https://doaj.org/article/4bbbbb0865f4495b858a449ab70a0dd5
Autor:
Carmen M. Warren, Jessica Tenney, Anna Sarukhanov, Maria Luisa Iruela-Arispe, Fabiana Csukasi, Ivan Duran, Deborah Krakow, Mark Skalansky
Publikováno v:
American journal of medical genetics. Part A, vol 176, iss 3
Duran, Ivan; Tenney, Jessica; Warren, Carmen M; Sarukhanov, Anna; Csukasi, Fabiana; Skalansky, Mark; et al.(2018). NRP1 haploinsufficiency predisposes to the development of Tetralogy of Fallot. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 176(3), 649-656. doi: 10.1002/ajmg.a.38600. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/1kz8q700
Am J Med Genet A
Duran, Ivan; Tenney, Jessica; Warren, Carmen M; Sarukhanov, Anna; Csukasi, Fabiana; Skalansky, Mark; et al.(2018). NRP1 haploinsufficiency predisposes to the development of Tetralogy of Fallot. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 176(3), 649-656. doi: 10.1002/ajmg.a.38600. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/1kz8q700
Am J Med Genet A
Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect. It involves anatomical abnormalities that change the normal flow of blood through the heart resulting in low oxygenation. Although not all of the underlying causes of TOF
Autor:
Esra Güç, Safiyyah Ziyad, Michele De Palma, Ryan D. Freshman, Mario Leonardo Squadrito, Julia J. Mack, Witold W. Kilarski, Huanhuan He, Caroline Baer, Carmen M. Warren, M. Luisa Iruela-Arispe, Austin I. McDonald, Melody A. Swartz
Publikováno v:
He, H; Mack, JJ; Güç, E; Warren, CM; Squadrito, ML; Kilarski, WW; et al.(2016). Perivascular Macrophages Limit Permeability. Arteriosclerosis, Thrombosis, and Vascular Biology, 36(11), 2203-2212. doi: 10.1161/ATVBAHA.116.307592. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2mq001hp
Arteriosclerosis, thrombosis, and vascular biology, vol 36, iss 11
Arteriosclerosis thrombosis and vascular biology
Arteriosclerosis, thrombosis, and vascular biology, vol 36, iss 11
Arteriosclerosis thrombosis and vascular biology
Objective— Perivascular cells, including pericytes, macrophages, smooth muscle cells, and other specialized cell types, like podocytes, participate in various aspects of vascular function. However, aside from the well-established roles of smooth mu
Autor:
Amy M McCarthy-Torrens, Bert T. Lai, Matthew B. Coppock, James R. Heath, Carmen M Warren, Heather D. Agnew, Matthew N. Idso, JingXin Liang
Protein-catalyzed capture agents (PCCs) are synthetic and modular peptide-based affinity agents that are developed through the use of single generation in situ click chemistry screens against large peptide libraries. In such screens, the target prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9a82f1f1a22c0296330cb5adf367c5
https://europepmc.org/articles/PMC6731165/
https://europepmc.org/articles/PMC6731165/
Autor:
Puzheng Zhang, Andras Nagy, Samer M.I. Hussein, Derek van der Kooy, Peter D. Westenskow, Hoon Ki Sung, Brian G. Ballios, Zhijie Li, Takeshi Baba, Martin Friedlander, Alissa Cohen Greenwald, Sabiha Hacibekiroglu, Edith Aguilar, M. Luisa Iruela-Arispe, Iacovos P. Michael, James M. Rini, Valentina Marchetti, Laura Donaldson, Toshihide Kurihara, Carmen M. Warren
Publikováno v:
EMBO Molecular Medicine. 6:604-623
Current therapeutic antiangiogenic biologics used for the treatment of pathological ocular angiogenesis could have serious side effects due to their interference with normal blood vessel physiology. Here, we report the generation of novel antivascula
Autor:
Liron Gibbs-Bar, Gregory S. Shelness, Ilana Rogachev, Daniel Castranova, Liran Carmel, Kenna Shaw, Josette Ungos, Moshe Grunspan, Van N. Pham, Tom T. Chen, Oded Mayseless, Yona Ely, Steven A. Farber, Philip M. Murphy, Carmen M. Warren, Brant M. Weinstein, Wuzhou Wan, Guy Malkinson, Gabriella Allmog, Kameha R. Kidd, M. Luisa Iruela-Arispe, Karina Yaniv, Brigid D. Lo, Inbal Avraham-Davidi
Publikováno v:
Nature Medicine. 18:967-973
Despite the clear major contribution of hyperlipidemia to the prevalence of cardiovascular disease in the developed world, the direct effects of lipoproteins on endothelial cells have remained obscure and are under debate. Here we report a previously
Autor:
Dana H. Z. Robinson, Jennie P. Perryman, Kimberly R. Jacob Arriola, Michelle A. Doldren, Carmen M. Warren
Publikováno v:
Ethnicity & Health. 12:465-482
To describe and understand the attitudes, beliefs, and experiences towards organ and tissue donation among African American clergy in Atlanta, Georgia, USA. The secondary objective is to understand what messages clergy are providing to their parishio
Autor:
Carmen M. Warren, Pascal Miéville, Leanne Li, Mei-Wen Peng, Elizabeth Allen, Douglas Hanahan, Sadegh Saghafinia
Publikováno v:
Cell Reports
Cell Reports, Vol 15, Iss 6, Pp 1144-1160 (2016)
Cell Reports, Vol 15, Iss 6, Pp 1144-1160 (2016)
Summary Therapeutic targeting of tumor angiogenesis with VEGF inhibitors results in demonstrable, but transitory efficacy in certain human tumors and mouse models of cancer, limited by unconventional forms of adaptive/evasive resistance. In one such
Autor:
Abigail S. Krall, Lewei Duan, M. Luisa Iruela-Arispe, Alexander M. van der Bliek, Safiyyah Ziyad, Michael Potente, Vaspour Antanesian, Katharina Happel, David Elashoff, Sunyoung Lee, Carmen M. Warren, Antoni X. Torres-Collado, Heather R. Christofk, Lawrence W. Castellani, Courtney K. Domigan
Publikováno v:
Domigan, CK; Warren, CM; Antanesian, V; Happel, K; Ziyad, S; Lee, S; et al.(2015). Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy. Journal of Cell Science, 128(12), 2236-2248. doi: 10.1242/jcs.163774. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9wm2278j
Journal of cell science, vol 128, iss 12
Journal of cell science, vol 128, iss 12
Autocrine VEGF is necessary for endothelial survival, although the cellular mechanisms supporting this function are unknown. Here, we show that – even after full differentiation and maturation – continuous expression of VEGF by endothelial cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4f31494c46c8453b5fbeb9b3a0db0d
http://www.escholarship.org/uc/item/9wm2278j
http://www.escholarship.org/uc/item/9wm2278j
Autor:
Carsten Rudat, Matteo Pellegrini, Marlin Touma, Jennifer J. Hofmann, Carmen M. Warren, Rannar Airik, Karen M. Lyons, Andreas Kispert, Jing Lu, M. Luisa Iruela-Arispe, Gerry Weinmaster, Yibin Wang, Anaïs Briot, Artur Jaroszewicz
Publikováno v:
Developmental cell, vol 31, iss 6
Briot, A; Jaroszewicz, A; Warren, CM; Lu, J; Touma, M; Rudat, C; et al.(2014). Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Developmental Cell, 31(6), 707-721. doi: 10.1016/j.devcel.2014.11.023. UCLA: Retrieved from: http://www.escholarship.org/uc/item/66x666mp
Briot, A; Jaroszewicz, A; Warren, CM; Lu, J; Touma, M; Rudat, C; et al.(2014). Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Developmental Cell, 31(6), 707-721. doi: 10.1016/j.devcel.2014.11.023. UCLA: Retrieved from: http://www.escholarship.org/uc/item/66x666mp
© 2014 Elsevier Inc. Acquisition and maintenance of vascular smooth muscle fate are essential for the morphogenesis and function of the circulatory system. Loss of contractile properties or changes in the identity of vascular smooth muscle cells (vS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf5b5f6939f14768a940371d445cdd6
https://escholarship.org/uc/item/66x666mp
https://escholarship.org/uc/item/66x666mp