Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Carmen Lerner"'
Autor:
Carolin K. Koss, Christian T. Wohnhaas, Jonathan R. Baker, Cornelia Tilp, Michèl Przibilla, Carmen Lerner, Silvia Frey, Martina Keck, Cara M. M. Williams, Daniel Peter, Meera Ramanujam, Jay Fine, Florian Gantner, Matthew Thomas, Peter J. Barnes, Louise E. Donnelly, Karim C. El Kasmi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Carolin Koss et al. show that IL-36 produced from neutrophils is a key amplifier of lung inflammation in mice by activating neutrophils, macrophages and fibroblasts in cooperation with GM-CSF and the viral mimic poly(I:C). This study suggests that ta
Externí odkaz:
https://doaj.org/article/807afab62a534fbbbb0ab4d532e4b447
Autor:
Carolin K. Watson, Daniela Schloesser, Katrin Fundel-Clemens, Carmen Lerner, Svenja Gabler, Praveen Baskaran, Christian T. Wohnhaas, Stefanie Dichtl, Heinrich J. Huber, Kjetil Ask, Florian Gantner, Coralie Viollet, Matthew J. Thomas, Fidel Ramirez, Peter J. Murray, Karim C. El Kasmi
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 68:366-380
Pro-fibrotic and pro-homeostatic macrophage phenotypes remain ill-defined, both in vivo and in vitro impeding successful development of drugs that reprogram macrophages as an attractive therapeutic approach to manage fibrotic disease. The goal to of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7e08f11f8603c1242ae29a7b30063e
https://doi.org/10.1165/rcmb.2022-0021oc
https://doi.org/10.1165/rcmb.2022-0021oc
Autor:
Heinrich J. Huber, Coralie Viollet, Stefanie Dichtl, Koss Carolin, Wioletta Skronska-Wasek, Peter J. Murray, Carmen Lerner, Cornelia Tilp, Daniela Schlösser, Fidel Ramirez, Christian T. Wohnhaas, Karim C. El Kasmi, Silvia Frey, Katrin Fundel-Clemens, Florian Gantner, Matthew Thomas
Publikováno v:
Idiopathic interstitial pneumonias.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60a7c6779e3ce5e754efbc75f519b8a0
https://doi.org/10.1183/13993003.congress-2021.oa4335
https://doi.org/10.1183/13993003.congress-2021.oa4335
Autor:
Cornelia Tilp, M.J. Thomas, Katrin Fundel-Clemens, K C El Kasmi, Carmen Lerner, Carolin K. Koss, Peter J. Murray, Daniela Schlösser, Fidel Ramirez, Heinrich J. Huber, Coralie Viollet, Silvia Frey, Wioletta Skronska-Wasek, Florian Gantner, Stefanie Dichtl, Christian T. Wohnhaas
Publikováno v:
12.01 - Idiopathic interstitial pneumonias.
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive fibrosing interstitial lung disease with poor prognosis. The current standard-of-care for IPF is the kinase inhibitor nintedanib, which has a distinct inhibitory profile targeting a ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f95b8d3d37521e2f930510d621ce4f8a
https://doi.org/10.1183/23120541.lsc-2021.92
https://doi.org/10.1183/23120541.lsc-2021.92
Autor:
Karim C. El Kasmi, Florian Gantner, Cara M. M. Williams, Silvia Frey, Michèl Przibilla, Meera Ramanujam, Louise E Donnelly, Cornelia Tilp, Carolin K. Koss, Peter J. Barnes, Martina Keck, Jay S. Fine, Daniel Peter, Jonathan R. Baker, Carmen Lerner, M.J. Thomas, Christian T. Wohnhaas
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
IL-36, which belongs to the IL-1 superfamily, is increasingly linked to neutrophilic inflammation. Here, we combined in vivo and in vitro approaches using primary mouse and human cells, as well as, acute and chronic mouse models of lung inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f46ac5112d428123cf8b853b50701c
https://doi.org/10.1038/s42003-021-01703-3
https://doi.org/10.1038/s42003-021-01703-3