Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Carmen Ledesma‐Feliciano"'
Autor:
Jay W. Hooper, Steven A. Kwilas, Matthew Josleyn, Sarah Norris, Jack N. Hutter, Melinda Hamer, Jeffrey Livezey, Kristopher Paolino, Patrick Twomey, Michael Koren, Paul Keiser, James E. Moon, Ugo Nwaeze, Jason Koontz, Carmen Ledesma-Feliciano, Nathalie Landry, Trevor Wellington
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Hantaan virus (HTNV) and Puumala virus (PUUV) are pathogenic zoonoses found in Asia and Europe, respectively. We conducted a randomized Phase 1 clinical trial of individual HTNV and PUUV DNA vaccines targeting the envelope glycoproteins (GnG
Externí odkaz:
https://doaj.org/article/09a21f68e1904d48a992bd029941bd0e
Autor:
Brian F. Niemeyer, Caitlin M. Miller, Carmen Ledesma‐Feliciano, James H. Morrison, Rocio Jimenez‐Valdes, Clarissa Clifton, Eric M. Poeschla, Kambez H. Benam
Publikováno v:
Nano Select, Vol 3, Iss 2, Pp 437-449 (2022)
Abstract Antiviral strategies that target host systems needed for SARS‐CoV‐2 replication and pathogenesis may have therapeutic potential and help mitigate resistance development. Here, we evaluate nafamostat mesylate, a potent broad‐spectrum se
Externí odkaz:
https://doaj.org/article/8e8f02fb26a74936a5b8bcf03d8097e3
Autor:
Carmen Ledesma-Feliciano, Ros Chapman, Jay W. Hooper, Kira Elma, Darin Zehrung, Miles B. Brennan, Erin K. Spiegel
Publikováno v:
Vaccines, Vol 11, Iss 2, p 280 (2023)
DNA vaccines have inherent advantages compared to other vaccine types, including safety, rapid design and construction, ease and speed to manufacture, and thermostability. However, a major drawback of candidate DNA vaccines delivered by needle and sy
Externí odkaz:
https://doaj.org/article/e5c745591d664e3284ead0b9a9f3a1bc
Autor:
Carmen Ledesma-Feliciano, Sarah Hagen, Ryan Troyer, Xin Zheng, Esther Musselman, Dragana Slavkovic Lukic, Ann-Mareen Franke, Daniel Maeda, Jörg Zielonka, Carsten Münk, Guochao Wei, Sue VandeWoude, Martin Löchelt
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-21 (2018)
Abstract Background Hosts are able to restrict viral replication to contain virus spread before adaptive immunity is fully initiated. Many viruses have acquired genes directly counteracting intrinsic restriction mechanisms. This phenomenon has led to
Externí odkaz:
https://doaj.org/article/8db1899cd87b4a8581c95ba397297c7b
Publikováno v:
Journal of Developmental Biology, Vol 9, Iss 4, p 54 (2021)
With over 4.8 million deaths within 2 years, time is of the essence in combating COVID-19. The infection now shows devastating impacts on the younger population, who were not previously predicted to be vulnerable, such as in the older population. COV
Externí odkaz:
https://doaj.org/article/f7db79c522ea44b8825384e1f6bd4420
Autor:
Carmen Ledesma-Feliciano, Ryan M. Troyer, Xin Zheng, Craig Miller, Rachel Cianciolo, Matteo Bordicchia, Nicholas Dannemiller, Roderick Gagne, Julia Beatty, Jessica Quimby, Martin Löchelt, Sue VandeWoude
Publikováno v:
Viruses, Vol 11, Iss 7, p 662 (2019)
Foamy viruses (FVs) are globally prevalent retroviruses that establish apparently apathogenic lifelong infections. Feline FV (FFV) has been isolated from domestic cats with concurrent diseases, including urinary syndromes. We experimentally infected
Externí odkaz:
https://doaj.org/article/c688d6f1e8dc4c3ca2a4cbd821ab4272
Autor:
Sarah R. Kechejian, Nick Dannemiller, Simona Kraberger, Carmen Ledesma-Feliciano, Jennifer Malmberg, Melody Roelke Parker, Mark Cunningham, Roy McBride, Seth P. D. Riley, Winston T. Vickers, Ken Logan, Mat Alldredge, Kevin Crooks, Martin Löchelt, Scott Carver, Sue VandeWoude
Publikováno v:
Viruses, Vol 11, Iss 4, p 359 (2019)
Feline foamy virus (FFV) is a retrovirus that has been detected in multiple feline species, including domestic cats (Felis catus) and pumas (Puma concolor). FFV results in persistent infection but is generally thought to be apathogenic. Sero-prevalen
Externí odkaz:
https://doaj.org/article/58cd08dc8331479d9e241b1709b120cc
Publikováno v:
Journal of Developmental Biology
Journal of Developmental Biology, Vol 9, Iss 54, p 54 (2021)
Journal of Developmental Biology, Vol 9, Iss 54, p 54 (2021)
With over 4.8 million deaths within 2 years, time is of the essence in combating COVID-19. The infection now shows devastating impacts on the younger population, who were not previously predicted to be vulnerable, such as in the older population. COV
Autor:
Kambez H. Benam, Carmen Ledesma-Feliciano, Rocio J Jimenez-Valdes, Brian F. Niemeyer, Caitlin M Miller, Eric M. Poeschla, Clarissa Clifton, James H. Morrison
Publikováno v:
Nano Select
Nano Select, Vol 3, Iss 2, Pp 437-449 (2022)
Nano Select, Vol 3, Iss 2, Pp 437-449 (2022)
Antiviral strategies that target host systems needed for SARS‐CoV‐2 replication and pathogenesis may have therapeutic potential and help mitigate resistance development. Here, we evaluate nafamostat mesylate, a potent broad‐spectrum serine prot
Autor:
Sue VandeWoude, Esther Musselman, Xin Zheng, Sarah Hagen, Jörg Zielonka, Daniel G. Maeda, Guochao Wei, Martin Löchelt, Ann-Mareen Franke, Carsten Münk, Ryan M. Troyer, Carmen Ledesma-Feliciano, Dragana Slavkovic Lukic
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-21 (2018)
Retrovirology
Retrovirology
Background Hosts are able to restrict viral replication to contain virus spread before adaptive immunity is fully initiated. Many viruses have acquired genes directly counteracting intrinsic restriction mechanisms. This phenomenon has led to a co-evo