Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Carmen La Porta"'
Autor:
Timo A. Nees, Na Wang, Pavel Adamek, Nadja Zeitzschel, Clement Verkest, Carmen La Porta, Irina Schaefer, Julie Virnich, Selin Balkaya, Vincenzo Prato, Chiara Morelli, Valerie Begay, Young Jae Lee, Anke Tappe-Theodor, Gary R. Lewin, Paul A. Heppenstall, Francisco J. Taberner, Stefan G. Lechner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Silent nociceptors remained enigmatic ever since they were first described decades ago. Here, Nees. et al. show that inflammation-induced upregulation of TMEM100 unsilences silent nociceptors, which triggers secondary mechanical pain hypersensitivity
Externí odkaz:
https://doaj.org/article/ad36199c53bf4668bb1d766ff2c256d7
Autor:
Daniel Segelcke, Steven R. Talbot, Rupert Palme, Carmen La Porta, Esther Pogatzki-Zahn, André Bleich, Anke Tappe-Theodor
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Rodent behavior is affected by different environmental conditions. These do not only comprise experimental and housing conditions but also familiarization with the experimenter. However, specific effects on pain-related behavior and chronic
Externí odkaz:
https://doaj.org/article/788100ff5b8f4b248daeb80341709821
Autor:
Timo A. Nees, Na Wang, Pavel Adamek, Clement Verkest, Carmen La Porta, Irina Schaefer, Julie Virnich, Selin Balkaya, Vincenzo Prato, Chiara Morelli, Nadja Zeitzschel, Valerie Begay, Young Jae Lee, Anke Tappe-Theodor, Gary R. Lewin, Paul A. Heppenstall, Francisco J. Taberner, Stefan G. Lechner
SummarySilent nociceptors are sensory afferents that are insensitive to noxious mechanical stimuli under normal conditions but become sensitized to such stimuli during inflammation. Using RNA-sequencing and quantitative RT-PCR we demonstrate that inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89460af4310a8b91006c729c3bee9b82
https://doi.org/10.1101/2022.04.07.486730
https://doi.org/10.1101/2022.04.07.486730
Autor:
Anke Tappe-Theodor, Carmen La Porta
Publikováno v:
Pain. 161(7)
Low back pain (LBP) is a highly prevalent and disabling condition whose initiating factors are poorly understood. It is known that psychological and physical stress is associated with LBP but the causal relationship, mechanisms, and mediators have no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9095c24ee4462879e9d713ce0da67930
https://pubmed.ncbi.nlm.nih.gov/32132393
https://pubmed.ncbi.nlm.nih.gov/32132393
Publikováno v:
European journal of pain (London, England). 23(2)
Background Chronic pain is often accompanied by comorbidities like anxiety and depression. The temporal correlations, as well as the underlying mechanisms of these reciprocal correlations, are unclear. Moreover, preclinical studies examining emotiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6722814e2d20b16a0014ecd08b0014cb
https://pubmed.ncbi.nlm.nih.gov/30098102
https://pubmed.ncbi.nlm.nih.gov/30098102
Publikováno v:
European Journal of Pain. 23:1049-1050
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46a561957a9912f9a66a6268ba5fab18
https://doi.org/10.1002/ejp.1396
https://doi.org/10.1002/ejp.1396
Autor:
Rafael de la Torre, Jone Llorente-Onaindia, Jorge Manzanares, María Salud García-Gutiérrez, Jordi Monfort, Carmen La Porta, S. Andreea Bura, Antoni Pastor, Rafael Maldonado, Francisco Navarrete
Publikováno v:
Pain
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat. Dipósit de la Recerca de Catalunya
instname
Supplemental Digital Content is Available in the Text. CB1R and CB2R differentially modulate the affective manifestations but not the cognitive impairment associated with osteoarthritis pain.
In this study, we investigated the role of the endoca
In this study, we investigated the role of the endoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8dd9ac0e0b41f6e2b6f30f1ad8dc2de
http://europepmc.org/articles/PMC4770330
http://europepmc.org/articles/PMC4770330
Publikováno v:
The European journal of neuroscience. 39(3)
Osteoarthritis is a degenerative joint disease associated with articular cartilage degradation. The major clinical outcome of osteoarthritis is a complex pain state that includes both nociceptive and neuropathic mechanisms. Currently, the therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042c7c07678b98760d923c6b68c5430a
https://pubmed.ncbi.nlm.nih.gov/24494687
https://pubmed.ncbi.nlm.nih.gov/24494687
Publikováno v:
European journal of pharmacology. 716(1-3)
The endogenous opioid and cannabinoid systems are involved in the physiological inhibitory control of pain and are of particular interest for the development of therapeutic approaches for pain management. The involvement of these endogenous systems i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a71ccb77ab53bb6ad57fc703f2a60b
https://pubmed.ncbi.nlm.nih.gov/23523475
https://pubmed.ncbi.nlm.nih.gov/23523475
Autor:
Paolo Epaminonda, Paolo Beck-Peccoz, Maura Arosio, Andrea Lania, Anna Spada, Laura Montefusco, Marco Losa, Francesca Coletti, Luca Olgiati, Marcello Filopanti, Cristina L. Ronchi, Carmen La-Porta
Publikováno v:
Clinical endocrinology. 72(5)
Objective A common polymorphic variant of the growth hormone receptor (GHR) is because of genomic deletion of exon 3 and has been linked with increased responsiveness to exogenous GH. The impact of this polymorphism in acromegaly, a disease character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbc682ec30cecf9b2842bdd5d4b9854
https://pubmed.ncbi.nlm.nih.gov/20447065
https://pubmed.ncbi.nlm.nih.gov/20447065