Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Carmen L. Krüger"'
Autor:
Thorsten Wohland, Sebastian Malkusch, Tim N. Baldering, Gerhard Hummer, Klara R. Mertinkus, Mike Heilemann, Nina S. Deussner-Helfmann, Marina S. Dietz, Hans-Dieter Barth, Christos Karathanasis, Mark S. Schröder, Carolin Böger, Carmen L. Krüger, Marie-Lena I. E. Harwardt
Publikováno v:
Single Molecule Spectroscopy and Superresolution Imaging XII.
Knowledge of assembly, subunit architecture and dynamics of membrane proteins in a cellular context is essential to infer their biological function. Optical super-resolution techniques provide the necessary spatial resolution to study these propertie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e4d12c9bab5a83b0dd6c35bc39a8e10
https://doi.org/10.1117/12.2522348
https://doi.org/10.1117/12.2522348
Autor:
Karen Bieback, Carmen L. Krüger, Katharina Volk, Graeme S. Cottrell, Darius Widera, Mike Heilemann, Marie-Theres Zeuner
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1863:3084-3095
A distinct feature of the Toll-like receptor 4 (TLR4) is its ability to trigger both MyD88-dependent and MyD88-independent signalling, culminating in activation of pro-inflammatory NF-κB and/or the antiviral IRF3. Although TLR4 agonists (lipopolysac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46949a6feedb430aff4f03d5c7b64500
https://doi.org/10.1016/j.bbamcr.2016.09.016
https://doi.org/10.1016/j.bbamcr.2016.09.016
Autor:
Fang Zhang, Sebastian Malkusch, Mike Heilemann, Lea Zimmermann, Franziska Herrmann, Christopher E. Goldring, B. Kevin Park, Robert P. Jones, Angela Oppelt, Daniel Kaschek, Suzanna Huppelschoten, Hassan Malik, Carmen L. Krüger, Benjamin Merkt, Jens Timmer, Ursula Klingmüller, Mara Meub, Amy Schofield, Rowena Sison-Young, Marie Buck-Wiese, Bob van de Water, Marcel Schilling
Publikováno v:
npj Systems Biology and Applications
NPJ Systems Biology and Applications
npj Systems Biology and Applications, 4, 23
npj Systems Biology and Applications, Vol 4, Iss 1, Pp 1-16 (2018)
NPJ Systems Biology and Applications
npj Systems Biology and Applications, 4, 23
npj Systems Biology and Applications, Vol 4, Iss 1, Pp 1-16 (2018)
Drug-induced liver injury (DILI) has become a major problem for patients and for clinicians, academics and the pharmaceutical industry. To date, existing hepatotoxicity test systems are only poorly predictive and the underlying mechanisms are still u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de450ad97aa24dfcfaaa163f8f317035
https://doi.org/10.1038/s41540-018-0058-z
https://doi.org/10.1038/s41540-018-0058-z
In humans, invading pathogens are recognized by Toll-like receptors (TLRs). Upon recognition of lipopolysaccharide (LPS) derived from the cell wall of gram-negative bacteria, TLR4 dimerizes and can stimulate two different signaling pathways, the proi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2597b8419be7fd9a1ddd154806828e7
https://centaur.reading.ac.uk/73191/1/aan1308_ArticleContent_v8.pdf
https://centaur.reading.ac.uk/73191/1/aan1308_ArticleContent_v8.pdf
Autor:
Mike Heilemann, Marina S. Dietz, Gerhard Hummer, Carmen L. Krüger, Sebastian Malkusch, Franziska Fricke, Christos Karathanasis
Publikováno v:
Single Molecule Spectroscopy and Superresolution Imaging X.
We report on quantitative single-molecule localization microscopy, a method that next to super-resolved images of cellular structures provides information on protein copy numbers in protein clusters. This approach is based on the analysis of blinking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9230425429eacb44ec23994887b6a375
https://doi.org/10.1117/12.2256638
https://doi.org/10.1117/12.2256638