Zobrazeno 1 - 10
of 493
pro vyhledávání: '"Carmen J, Marsit"'
Autor:
Kenyaita M. Hodge, Amber A. Burt, Marie Camerota, Brian S. Carter, Jennifer Check, Karen N. Conneely, Jennifer Helderman, Julie A. Hofheimer, Anke Hüls, Elisabeth C. McGowan, Charles R. Neal, Steven L. Pastyrnak, Lynne M. Smith, Sheri A. DellaGrotta, Lynne M. Dansereau, T. Michael O’Shea, Carmen J. Marsit, Barry M. Lester, Todd M. Everson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The time from conception through the first year of life is the most dynamic period in human development. This time period is particularly important for infants born very preterm (
Externí odkaz:
https://doaj.org/article/00ebc431d2c24149985591644f345a5d
Autor:
Emily R. Hannon, Carmen J. Marsit, Arlene E. Dent, Paula Embury, Sidney Ogolla, David Midem, Scott M. Williams, James W. Kazura
Publikováno v:
BioData Mining, Vol 17, Iss 1, Pp 1-16 (2024)
Abstract Background Changing cell-type proportions can confound studies of differential gene expression or DNA methylation (DNAm) from peripheral blood mononuclear cells (PBMCs). We examined how cell-type proportions derived from the transcriptome ve
Externí odkaz:
https://doaj.org/article/8597c2e5e77243ba82997ddda9ac652c
Autor:
Elizabeth C. Anderson, Helen B. Foley, Joshua J. Levy, Megan E. Romano, Jiang Gui, Jessica L. Bentz, Luis E. Maldonado, Shohreh F. Farzan, Theresa M. Bastain, Carmen J. Marsit, Carrie V. Breton, Caitlin G. Howe
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
Maternal hyperglycemia during pregnancy adversely affects maternal and child outcomes. While mechanisms are not fully understood, maternal circulating miRNAs may play a role. We examined whether continuous glucose levels and hyperglycemia subtypes (g
Externí odkaz:
https://doaj.org/article/48ce9192910142c18f6334ac7d22f816
Publikováno v:
Stress, Vol 27, Iss 1 (2024)
AbstractPerinatal stress is associated with altered placental methylation, which plays a critical role in fetal development and infant outcomes. This proof-of-concept pilot study investigated the impact of lifetime trauma exposure and perinatal PTSD
Externí odkaz:
https://doaj.org/article/09b335bc345d4e55beb30336ef1cc439
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACT5-hydroxymethylcystosine (5hmC), is an intermediate product in the DNA demethylation pathway, but may act as a functional epigenetic modification. We have conducted the largest study of site-specific 5hmC in placenta to date using parallel bi
Externí odkaz:
https://doaj.org/article/37b37fb99ca64922b632e1120751f889
Autor:
Marie Camerota, Barry M. Lester, Francisco Xavier Castellanos, Brian S. Carter, Jennifer Check, Jennifer Helderman, Julie A. Hofheimer, Elisabeth C. McGowan, Charles R. Neal, Steven L. Pastyrnak, Lynne M. Smith, Thomas Michael O’Shea, Carmen J. Marsit, Todd M. Everson
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Prior research has identified epigenetic predictors of attention problems in school-aged children but has not yet investigated these in young children, or children at elevated risk of attention problems due to preterm birth. The current stud
Externí odkaz:
https://doaj.org/article/360b1bec8ab34c20ac132d6cdeb6e0d0
Autor:
Fang Fang, Linran Zhou, Wei Perng, Carmen J. Marsit, Anna K. Knight, Andres Cardenas, Max T. Aung, Marie-France Hivert, Izzuddin M. Aris, Jaclyn M. Goodrich, Alicia K. Smith, Abigail Gaylord, Rebecca C. Fry, Emily Oken, George O’Connor, Douglas M. Ruden, Leonardo Trasande, Julie B. Herbstman, Carlos A. Camargo, Nicole R. Bush, Anne L. Dunlop, Dana M. Dabelea, Margaret R. Karagas, Carrie V. Breton, Carole Ober, Todd M. Everson, Grier P. Page, Christine Ladd-Acosta, on behalf of program collaborators for Environmental influences on Child Health Outcomes
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination. Results Our study used data from seven tissue types on
Externí odkaz:
https://doaj.org/article/ba76599e9e1d4dfbacb72eaf17f477e9
Autor:
Hudson P. Santos, Adam E. Enggasser, Jeliyah Clark, Kyle Roell, Vasyl Zhabotynsky, William Adam Gower, Diana Yanni, Nou Gao Yang, Lisa Washburn, Semsa Gogcu, Carmen J. Marsit, Karl Kuban, T. Michael O’Shea, Rebecca C. Fry
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Health outcomes among children born prematurely are known to be sexually dimorphic, with male infants often more affected, yet the mechanism behind this observation is not clear. CpG methylation levels in the placenta and blood al
Externí odkaz:
https://doaj.org/article/0f3aca2517494df387b46f79ff24c43f
Autor:
Uriel Paniagua, Barry M. Lester, Carmen J. Marsit, Marie Camerota, Brian S. Carter, Jennifer F. Check, Jennifer Helderman, Julie A. Hofheimer, Elisabeth C. McGowan, Charles R. Neal, Steven L. Pastyrnak, Lynne M. Smith, Sheri A. DellaGrotta, Lynne M. Dansereau, T. Michael O’Shea, Todd M. Everson
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
ABSTRACTEpigenetic age acceleration is a risk factor for chronic diseases of ageing and may reflect aspects of biological ageing. However, few studies have examined epigenetic ageing during the early neonatal period in preterm infants, who are at hei
Externí odkaz:
https://doaj.org/article/42d2073c91744e12bc307ea5c470af95
Autor:
Catherine M. Bulka, Todd M. Everson, Amber A. Burt, Carmen J. Marsit, Margaret R. Karagas, Kristen E. Boyle, Sierra Niemiec, Katerina Kechris, Elizabeth J. Davidson, Ivana V. Yang, Jason I. Feinberg, Heather E. Volk, Christine Ladd-Acosta, Carrie V. Breton, T. Michael O’Shea, Rebecca C. Fry
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
The placenta undergoes many changes throughout gestation to support the evolving needs of the foetus. There is also a growing appreciation that male and female foetuses develop differently in utero, with unique epigenetic changes in placental tissue.
Externí odkaz:
https://doaj.org/article/ac82bc0e677b4fe1971c034cf1d44fb9