Cellular Crosstalk between Endothelial and Smooth Muscle Cells in Vascular Wall Remodeling

Autor: Nerea Méndez-Barbero, Carmen Gutiérrez-Muñoz, Luis Miguel Blanco-Colio

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 14, p 7284 (2021)

Pathological vascular wall remodeling refers to the structural and functional changes of the vessel wall that occur in response to injury that eventually leads to cardiovascular disease (CVD). Vessel wall are composed of two major primary cells types

Externí odkaz: https://doaj.org/article/eb1044cc12ec411695cd47c748da2675

Bosutinib Inhibits EGFR Activation in Head and Neck Cancer

Autor: Carmen Segrelles, David Contreras, Elena M. Navarro, Carmen Gutiérrez-Muñoz, Ramón García-Escudero, Jesús M. Paramio, Corina Lorz

Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 7, p 1824 (2018)

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, and although new therapeutic approaches have been recently evaluated, overall patient survival is still poor. Thus, new effective and selective clinical treatmen

Externí odkaz: https://doaj.org/article/eab7a6e18f4a422ab25446b0fb11030c

Anexinas: implicación en la homeostasis del colesterol, la respuesta inflamatoria y la aterosclerosis

Autor: Rafael Blázquez-Serra, Luis Miguel Blanco-Colio, José Luis Martín-Ventura, Nerea Méndez-Barbero, Carmen Gutiérrez-Muñoz

Publikováno v: Clínica e Investigación en Arteriosclerosis. 33:206-216

Resumen La superfamilia de anexinas esta constituida por 12 proteinas con alta homologia estructural que se unen a fosfolipidos de membrana de una manera dependiente de Ca2+. Diferentes estudios de sobreexpresion, inhibicion o usando proteinas recomb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::006822806bd3205e4b08c6d05d439a66
https://doi.org/10.1016/j.arteri.2020.12.010

A major role of TWEAK/Fn14 axis as a therapeutic target for post-angioplasty restenosis

Autor: Pablo Minguez, Jesús Egido, Nerea Méndez-Barbero, José Luis Martín-Ventura, Jean-Baptiste Michel, Carmen Gutiérrez-Muñoz, Vanesa Esteban, Julio Madrigal-Matute, Luis Miguel Blanco-Colio

Publikováno v: EBioMedicine, Vol 46, Iss, Pp 274-289 (2019)
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
EBioMedicine
Biblos-e Archivo. Repositorio Institucional de la UAM
instname

Background: Tumor necrosis factor-like weak inducer of apoptosis (Tnfsf12; TWEAK) and its receptor Fibroblast growth factor-inducible 14 (Tnfrsf12a; Fn14) participate in the inflammatory response associated with vascular remodeling.However, the funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f299b331e6320a5f67c8764e185a40
http://www.sciencedirect.com/science/article/pii/S2352396419305146

CD163 deficiency increases foam cell formation and plaque progression in atherosclerotic mice

Autor: Pia Svendsen, Joan Carles Escolà-Gil, Patricia Quesada, Nerea Méndez-Barbero, Søren K. Moestrup, Jesús Egido, Valvanera Fernández-Laso, José Luis Martín-Ventura, Luis Miguel Blanco-Colio, Carmen Gutiérrez-Muñoz, Cristina Sastre

Publikováno v: Gutiérrez-Muñoz, C, Méndez-Barbero, N, Svendsen, P, Sastre, C, Fernández-Laso, V, Quesada, P, Egido, J, Escolá-Gil, J C, Martín-Ventura, J L, Moestrup, S K & Blanco-Colio, L M 2020, ' CD163 deficiency increases foam cell formation and plaque progression in atherosclerotic mice ', FASEB Journal, vol. 34, no. 11, pp. 14960-14976 . https://doi.org/10.1096/fj.202000177R
Digital.CSIC. Repositorio Institucional del CSIC
instname

Atherosclerosis is an inflammatory disease characterized by the accumulation of macrophages in the vessel wall. Macrophages depend on their polarization to exert either pro-inflammatory or anti-inflammatory effects. Macrophages of the anti-inflammato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfab7dd56ba1400fe772aa81163d36f
https://pubmed.ncbi.nlm.nih.gov/32924185