Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Carmen Gomez-Guerrero"'
Autor:
Ignacio Prieto, María Kavanagh, Luna Jimenez-Castilla, Marisa Pardines, Iolanda Lazaro, Isabel Herrero del Real, Monica Flores-Muñoz, Jesus Egido, Oscar Lopez-Franco, Carmen Gomez-Guerrero
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102041- (2023)
Diabetic kidney disease (DKD) is a common microvascular complication of diabetes, a global health issue. Hyperglycemia, in concert with cytokines, activates the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway to ind
Externí odkaz:
https://doaj.org/article/22cf8225344640efab8c0fb9c322b23f
Autor:
Laura Lopez‐Sanz, Susana Bernal, Luna Jimenez‐Castilla, Ignacio Prieto, Sara La Manna, Sergio Gomez‐Lopez, Luis Miguel Blanco‐Colio, Jesus Egido, Jose Luis Martin‐Ventura, Carmen Gomez‐Guerrero
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 7, Pp n/a-n/a (2021)
Abstract Background Abdominal aortic aneurysm (AAA), a degenerative vascular pathology characterized by permanent dilation of the aorta, is considered a chronic inflammatory disease involving innate/adaptive immunity. However, the functional role of
Externí odkaz:
https://doaj.org/article/e9523401409845d683320b3209e0d631
Autor:
Laura Del Puerto‐Nevado, Aranzazu Santiago‐Hernandez, Sonia Solanes‐Casado, Nieves Gonzalez, Marta Ricote, Marta Corton, Isabel Prieto, Sebastian Mas, Ana Belen Sanz, Oscar Aguilera, Carmen Gomez‐Guerrero, Carmen Ayuso, Alberto Ortiz, Federico Rojo, Jesus Egido, Jesus Garcia‐Foncillas, Pablo Minguez, Gloria Alvarez‐Llamas, on behalf of the DiabetesCancerConnect Consortium
Publikováno v:
Molecular Oncology, Vol 13, Iss 9, Pp 1887-1897 (2019)
Type 2 diabetes mellitus (T2DM) has been associated with an increased risk of cancer, including colon cancer (CC). However, we recently reported no influence of T2DM on CC prognosis, suggesting that any effect might be at the early stages of tumor de
Externí odkaz:
https://doaj.org/article/2d414700dbd5494194adaa5a938914cc
Autor:
Laura Del Puerto‐Nevado, Pablo Minguez, Marta Corton, Sonia Solanes‐Casado, Isabel Prieto, Sebastian Mas, Ana Belen Sanz, Paula Gonzalez‐Alonso, Cristina Villaverde, Sergio Portal‐Nuñez, Oscar Aguilera, Carmen Gomez‐Guerrero, Pedro Esbrit, Fernando Vivanco, Nieves Gonzalez, Carmen Ayuso, Alberto Ortiz, Federico Rojo, Jesus Egido, Gloria Alvarez‐Llamas, Jesus Garcia‐Foncillas, the DiabetesCancerConnect Consortium
Publikováno v:
Molecular Oncology, Vol 13, Iss 4, Pp 857-872 (2019)
The potential involvement of type 2 diabetes mellitus (T2DM) as a risk factor for colon cancer (CC) has been previously reported. While several clinical studies show a higher incidence of CC and a lower survival rate in diabetics, others report no as
Externí odkaz:
https://doaj.org/article/dcc57d50d777408bb199fbd0ef72fef9
Autor:
Lucas Opazo-Ríos, Yenniffer Sanchez Matus, Raúl R Rodrigues-Díez, Daniel Carpio, Alejandra Droguett, Jesús Egido, Carmen Gomez-Guerrero, Sergio Mezzano
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
Introduction Diabetic nephropathy (DN) is the leading cause of chronic kidney disease worldwide. The Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway participates in the development and progression of DN. Among the d
Externí odkaz:
https://doaj.org/article/d50279f81e274acc8ca0de6429a1a460
Autor:
Sara La Manna, Laura Lopez-Sanz, Susana Bernal, Luna Jimenez-Castilla, Ignacio Prieto, Giancarlo Morelli, Carmen Gomez-Guerrero, Daniela Marasco
Publikováno v:
Antioxidants, Vol 9, Iss 8, p 754 (2020)
The chronic activation of the Janus kinase/signal transducer and activator of the transcription (JAK/STAT) pathway is linked to oxidative stress, inflammation and cell proliferation. Suppressors of cytokine signaling (SOCS) proteins negatively regula
Externí odkaz:
https://doaj.org/article/a8bbd14781e4438c801a4d1eb5712f14
Autor:
Iolanda Lazaro, Laura Lopez-Sanz, Susana Bernal, Ainhoa Oguiza, Carlota Recio, Ana Melgar, Luna Jimenez-Castilla, Jesus Egido, Julio Madrigal-Matute, Carmen Gomez-Guerrero
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Interactive relationships between metabolism, inflammation, oxidative stress, and autophagy in the vascular system play a key role in the pathogenesis of diabetic cardiovascular disease. Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a stress-
Externí odkaz:
https://doaj.org/article/93a7b2e749ae41ba87219e1d8408d683
Autor:
Isabel Prieto, Laura Del Puerto-Nevado, Nieves Gonzalez, Sergio Portal-Nuñez, Sandra Zazo, Marta Corton, Pablo Minguez, Carmen Gomez-Guerrero, Jose Miguel Arce, Ana Belen Sanz, Sebastian Mas, Oscar Aguilera, Gloria Alvarez-Llamas, Pedro Esbrit, Alberto Ortiz, Carmen Ayuso, Jesus Egido, Federico Rojo, Jesus Garcia-Foncillas, DiabetesCancerConnect Consortium
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172300 (2017)
BACKGROUND:Multiple observational studies suggest an increased risk of colon cancer in patients with diabetes mellitus (DM). This can theoretically be the result of an influence of the diabetic environment on carcinogenesis or the tumor biologic beha
Externí odkaz:
https://doaj.org/article/093b7915bf0f48549b17b68362a443a7
Autor:
Beñat Mallavia, Ainhoa Oguiza, Oscar Lopez-Franco, Carlota Recio, Guadalupe Ortiz-Muñoz, Iolanda Lazaro, Virginia Lopez-Parra, Jesus Egido, Carmen Gomez-Guerrero
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66754 (2013)
Immunity contributes to arterial inflammation during atherosclerosis. Oxidized low-density lipoproteins induce an autoimmune response characterized by specific antibodies and immune complexes in atherosclerotic patients. We hypothesize that specific
Externí odkaz:
https://doaj.org/article/eef71a76a03d448188cc0ba4f7e51e08
Autor:
Luna Jimenez-Castilla, Ignacio Prieto, José Luis Martín-Ventura, Carmen Gomez-Guerrero, Ana Melgar, Sara La Manna, Jesús Egido, Laura Lopez-Sanz, Luis Miguel Blanco-Colio, Susana Bernal
Publikováno v:
British Journal of Pharmacology. 178:564-581
Background and purpose Abdominal aortic aneurysm (AAA) is a multifactorial disease characterized by chronic inflammation, oxidative stress, and proteolytic activity in the aortic wall. Targeting Janus kinase/signal transducer and activator of transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e94130ec2c2d93f878cf8cdbd996ee
https://doi.org/10.1111/bph.15330
https://doi.org/10.1111/bph.15330