Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Carmen Gerlach"'
Autor:
Jyoti Pokharel, Carmen Gerlach
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112548- (2023)
Through live imaging of CD8+ T cells carrying a fate reporter, Gräbnitz et al. directly linked (a)symmetric division to T cell fate.1 Asymmetry during the first division ensured the generation of stem-like CD8+ T cells following strong T cell stimul
Externí odkaz:
https://doaj.org/article/eb3a88324fe041a998d219f9da822c8f
Autor:
Patricia A. Possik, Judith Müller, Carmen Gerlach, Juliana C.N. Kenski, Xinyao Huang, Aida Shahrabi, Oscar Krijgsman, Ji-Ying Song, Marjon A. Smit, Bram Gerritsen, Cor Lieftink, Kristel Kemper, Magali Michaut, Roderick L. Beijersbergen, Lodewyk Wessels, Ton N. Schumacher, Daniel S. Peeper
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1375-1386 (2014)
To identify factors preferentially necessary for driving tumor expansion, we performed parallel in vitro and in vivo negative-selection short hairpin RNA (shRNA) screens. Melanoma cells harboring shRNAs targeting several DNA damage response (DDR) kin
Externí odkaz:
https://doaj.org/article/a4a4973345cf4a9daafaab7b6cdd3545
Publikováno v:
European journal of immunology, 53(3):2250305. Wiley-VCH Verlag
The magnitude of CD8 T-cell responses against intracellular pathogens is thought to primarily depend on the expansion capacity of naïve T cells, given that their recruitment is considered optimal. In the current issue of the European Journal of Immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cceba3dbcac4ae87d445de3bd31e3e4
https://pure.amc.nl/en/publications/noshows-in-tcell-responses-are-frequent-for-clones-of-low-tcell-receptor-affinity(806c32f4-0bdb-4367-8678-f21552adfa3e).html
https://pure.amc.nl/en/publications/noshows-in-tcell-responses-are-frequent-for-clones-of-low-tcell-receptor-affinity(806c32f4-0bdb-4367-8678-f21552adfa3e).html
Autor:
Roser Vento-Tormo, Kellie Ann Jurado, Conggang Zhang, Pedro Moraes-Vieira, Carmen Gerlach, Jose Ordovas-Montanes
Publikováno v:
Immunity
For new principal investigators, the first years are key to getting a laboratory off the ground and running. COVID-19 has changed the world, bringing on unforeseen difficulties and challenges at every level. We asked these investigators to share thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38fa25e0b51e9556f3694abf0736ee6
https://pubmed.ncbi.nlm.nih.gov/34644549
https://pubmed.ncbi.nlm.nih.gov/34644549
Autor:
Carmen Gerlach, Shaima Al Khabouri
Publikováno v:
Scandinavian Journal of Immunology
T cells responding to acute infections generally provide two key functions to protect the host: (1) active contribution to pathogen elimination and (2) providing long‐lived cells that are poised to rapidly respond to renewed infection, thus ensurin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc084b8bf82dc491213e9c995bf4a13a
http://europepmc.org/articles/PMC7757170
http://europepmc.org/articles/PMC7757170
Publikováno v:
Frontiers Research Topics ISBN: 9782889637959
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2b304cf8f134b8640010cecc286bd91
https://doi.org/10.3389/978-2-88963-795-9
https://doi.org/10.3389/978-2-88963-795-9
Autor:
Carmen Gerlach
Publikováno v:
Trends in Immunology. 39:167-170
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4663dc7dc564807d9cdeb7ee736d2fde
https://doi.org/10.1016/j.it.2018.01.004
https://doi.org/10.1016/j.it.2018.01.004
Publikováno v:
Immunity. 50:1119-1121
In this issue of Immunity, van der Veeken et al. (2019) leverage genetic variation between mouse strains to assess epigenetic and transcriptional regulation dynamics in CD8+ T cells responding to acute infection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d71e05bf2eb2dbfa8f78b99e7cc3dc5
https://doi.org/10.1016/j.immuni.2019.05.001
https://doi.org/10.1016/j.immuni.2019.05.001
Autor:
Liv Eidsmo, Carmen Gerlach
Publikováno v:
Trends in Immunology. 39:170-172
CD8 T cells are crucial for long-term immunity. Nevertheless, the in vivo differentiation of human naive CD8 T cells into effector and memory populations remains ill-defined. A recent study assesses the in vivo turnover of human antigen-specific CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e345cbb44b8f060e9aa4c9be882e23e
https://doi.org/10.1016/j.it.2018.01.003
https://doi.org/10.1016/j.it.2018.01.003