Zobrazeno 1 - 10
of 398
pro vyhledávání: '"Carmen García-Ruiz"'
Autor:
Ingrid Wei Zhang, María Belén Sánchez-Rodríguez, Cristina López-Vicario, Mireia Casulleras, Marta Duran-Güell, Roger Flores-Costa, Ferran Aguilar, Michael Rothe, Paula Segalés, Carmen García-Ruiz, José C. Fernández-Checa, Jonel Trebicka, Vicente Arroyo, Joan Clària
Publikováno v:
JHEP Reports, Vol 6, Iss 11, Pp 101187- (2024)
Background & Aims: In patients with cirrhosis, acute decompensation (AD) correlates with a hyperinflammatory state driven by mitochondrial dysfunction, which is a significant factor in the progression toward acute-on-chronic liver failure (ACLF). Ele
Externí odkaz:
https://doaj.org/article/78ae3b3c40b44e31b1e8fa153dd30e7a
Autor:
Paloma Ruiz-Blázquez, María Fernández-Fernández, Valeria Pistorio, Celia Martinez-Sanchez, Michele Costanzo, Paula Iruzubieta, Ekaterina Zhuravleva, Júlia Cacho-Pujol, Silvia Ariño, Alejandro Del Castillo-Cruz, Susana Núñez, Jesper B. Andersen, Margherita Ruoppolo, Javier Crespo, Carmen García-Ruiz, Luigi Michele Pavone, Thomas Reinheckel, Pau Sancho-Bru, Mar Coll, José C. Fernández-Checa, Anna Moles
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101989- (2024)
Background and objectives: Fibrosis contributes to 45% of deaths in industrialized nations and is characterized by an abnormal accumulation of extracellular matrix (ECM). There are no specific anti-fibrotic treatments for liver fibrosis, and previous
Externí odkaz:
https://doaj.org/article/4887cc29c02b483699490b149dfe04c7
Autor:
Leire Goicoechea, Sandra Torres, Laura Fàbrega, Mónica Barrios, Susana Núñez, Josefina Casas, Gemma Fabrias, Carmen García-Ruiz, José C. Fernández-Checa
Publikováno v:
Redox Biology, Vol 72, Iss , Pp 103150- (2024)
Niemann-Pick type C (NPC) disease is a lysosomal storage disorder characterized by impaired motor coordination due to neurological defects and cerebellar dysfunction caused by the accumulation of cholesterol in endolysosomes. Besides the increase in
Externí odkaz:
https://doaj.org/article/0f938206009740018271c5c1d330ac3d
Autor:
Judith Cantó‐Santos, Laura Valls‐Roca, Ester Tobías, Francesc Josep García‐García, Mariona Guitart‐Mampel, Anna Esteve‐Codina, Beatriz Martín‐Mur, Mercedes Casado, Rafael Artuch, Estel Solsona‐Vilarrasa, José Carlos Fernandez‐Checa, Carmen García‐Ruiz, Carles Rentero, Carlos Enrich, Pedro J. Moreno‐Lozano, José César Milisenda, Francesc Cardellach, Josep M. Grau‐Junyent, Glòria Garrabou
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 2, Pp 964-977 (2023)
Abstract Background Inclusion body myositis (IBM) is an inflammatory myopathy clinically characterized by proximal and distal muscle weakness, with inflammatory infiltrates, rimmed vacuoles and mitochondrial changes in muscle histopathology. There is
Externí odkaz:
https://doaj.org/article/0f82886d569447a682acbe705f05bfcc
Autor:
Raquel Fucho, Estel Solsona-Vilarrasa, Sandra Torres, Susana Nuñez, Naroa Insausti-Urkia, Albert Edo, Maria Calvo, Anna Bosch, Gemma Martin, Carlos Enrich, Carmen García-Ruiz, Jose C. Fernandez-Checa
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 8, Pp 100413- (2023)
Alcoholic-related liver disease (ALD) is one of the leading causes of chronic liver disease and morbidity. Unfortunately, the pathogenesis of ALD is still incompletely understood. StARD1 has emerged as a key player in other etiologies of chronic live
Externí odkaz:
https://doaj.org/article/a80cbd9789684781b60b96a0b071f59f
Autor:
Leire Goicoechea, Laura Conde de la Rosa, Sandra Torres, Carmen García-Ruiz, José C. Fernández-Checa
Publikováno v:
Redox Biology, Vol 61, Iss , Pp 102643- (2023)
Cholesterol is a crucial component of membrane bilayers by regulating their structural and functional properties. Cholesterol traffics to different cellular compartments including mitochondria, whose cholesterol content is low compared to other cell
Externí odkaz:
https://doaj.org/article/5c33b5659d2148daafd8ffb459a44fbb
Autor:
Cristina Alarcón-Vila, Naroa Insausti-Urkia, Sandra Torres, Paula Segalés-Rovira, Laura Conde de la Rosa, Susana Nuñez, Raquel Fucho, Jose C. Fernández-Checa, Carmen García-Ruiz
Publikováno v:
Redox Biology, Vol 59, Iss , Pp 102596- (2023)
Alcoholic (ASH) and nonalcoholic. (NASH).steatohepatitis are advanced.stages.of.fatty.liver.disease.Methionine adenosyltransferase 1A (MAT1A) plays a key role in hepatic methionine metabolism and germline Mat1a deletion in mice promotes NASH. Acid sp
Externí odkaz:
https://doaj.org/article/fa7b91131101420fb752ff6723e05135
Publikováno v:
Hepatology Communications, Vol 2, Iss 12, Pp 1425-1439 (2018)
Fatty liver disease is one of the most prevalent forms of chronic liver disease that encompasses both alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD). Alcoholic steatohepatitis (ASH) and nonalcoholic steatohepatitis (NASH)
Externí odkaz:
https://doaj.org/article/85abbf7b4842492ea20a51778b5a78f2
Publikováno v:
Cells, Vol 11, Iss 9, p 1475 (2022)
Alcoholic (ASH) and nonalcoholic steatohepatitis (NASH) are advanced stages of fatty liver disease and two of the most prevalent forms of chronic liver disease. ASH and NASH are associated with significant risk of further progression to cirrhosis and
Externí odkaz:
https://doaj.org/article/31f81b16055144e0bec3bc4fdbe0cc5e
Autor:
Luis Ramos-Guerrero, Gemma Montalvo, Marzia Cosmi, Carmen García-Ruiz, Fernando E. Ortega-Ojeda
Publikováno v:
Toxics, Vol 10, Iss 3, p 115 (2022)
The Raman analysis of marijuana is challenging because of the sample’s easy photo-degradation caused by the laser intensity. In this study, optimization of collection parameters and laser focusing on marijuana trichome heads allowed collecting Rama
Externí odkaz:
https://doaj.org/article/ac3ea2866e5741debb92404383b86732