Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Carmen García-Lecumberri"'
Autor:
Nuria del Olmo, Carmen García-Lecumberri, Alejandro Higuera-Matas, Emilio Ambrosio, Miguel Miguens
Publikováno v:
Pharmaceuticals, Vol 4, Iss 10, Pp 1315-1327 (2011)
The high rate of recidivism in cocaine addiction after prolonged periods of abstinence poses a significant problem for the effective treatment of this condition. Moreover, the neurobiological basis of this relapse phenomenon remains poorly understood
Externí odkaz:
https://doaj.org/article/39d84c94edc247b8a50fff17083d5764
Autor:
Amadeo Puerto, Emilio Ambrosio, Alejandro Higuera-Matas, Raquel Santos-Toscano, Marcos Ucha, Maria J. Simon, Carmen García-Lecumberri, David Roura-Martínez
Publikováno v:
Neurobiology of Learning and Memory. 127:17-26
Intracranial self-stimulation (ICSS) of the lateral hypothalamus (LH) is involved in the activation of neuroanatomical systems that are also associated with the processing of natural and other artificial rewarding stimuli. Specific components of this
Autor:
Santiago M. Coria, Miguel Miguéns, Emilio Ambrosio, Gonzalo L. Montoya, Alejandro Higuera-Matas, Carmen García-Lecumberri
Publikováno v:
Current Neuropharmacology
Drug addiction results from the interplay between social and biological factors. Among these, genetic variables play a major role. The use of genetically related inbred rat strains that differ in their preference for drugs of abuse is one approach of
Autor:
Carmen García-Lecumberri, Miguel Miguéns, Alejandro Higuera-Matas, Manuel Desco, María Luisa Soto-Montenegro, Nuria Del Olmo, Emilio Ambrosio, I. Torres, Juan José Vaquero, J. Sanchez
Publikováno v:
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
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Marijuana consumption during adolescence has been proposed to be a stepping stone for adult cocaine addiction. However, experimental evidence for this hypothesis is missing. In this work we chronically injected male and female Wistar rats with either
Autor:
Sonsoles Martı́n, Nuria Del Olmo, Alejandro Higuera-Matas, Emilio Ambrosio, Pilar Sánchez-Cardoso, Miguel Miguéns, Carmen García-Lecumberri
Publikováno v:
Neuropharmacology. 52:931-948
Lewis (LEW) and Fischer 344 (F344) rats show differential morphine self-administration rates. In this study, after animals of both strains self-administered morphine (1 mg/kg) or extinguished this behaviour for 3, 7 or 15 days, we measured the bindin
Autor:
Emilio Ambrosio, Jorge Manzanares, Javier Corchero, J.M. Oliva, Carmen García-Lecumberri, Sonsoles Martı́n
Publikováno v:
Journal of Psychopharmacology. 18:54-58
Several studies have demonstrated reciprocal, as well as synergistic interactions between cannabinoid and opioid systems. The aim of this study was to explore the time-related effects of repeated administration of δ9-tetrahydrocannabinol on µ-opioi
Autor:
José Antonio Crespo, Carmen García-Lecumberri, Emilio Ambrosio, Javier Corchero, Jorge Manzanares, José A. Fuentes, Sonsoles Martı́n
Publikováno v:
Brain Research. 821:350-355
We have previously shown that the acquisition rate of intravenous morphine self-administration under a fixed ratio one (FR1) schedule of reinforcement was greater in Lewis (LEW) than Fischer 344 (F344) rats. The purpose of the present experiment was
Autor:
Carmen García-Lecumberri, Luis F. Alguacil, Victoria Iglesias, Emilio Ambrosio, Luis M. Orensanz
Publikováno v:
Pharmacology Biochemistry and Behavior. 56:487-491
The alpha-2 receptor antagonist yohimbine has been previously shown to prevent the development of morphine dependence in a rat behavioral model. This study was directed to clarify the mechanism of this interaction, which is presently unknown. Since u
Autor:
Santiago M. Coria, Emilio Ambrosio, Marcos Ucha, Carmen García-Lecumberri, María Amparo Assis, Miguel Miguéns, Alejandro Higuera-Matas, David Roura-Martínez
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 53
The Lewis (LEW) and Fischer 344 (F344) rat strains have been proposed as a model to study certain genetic influences on drug use. These strains differ in terms of the self-administration of several drugs, and in their expression of various components
Autor:
Emilio Ambrosio, Javier Pascau, Miguel Miguéns, Verónica García-Vázquez, Carmen García-Lecumberri, Nuria Del Olmo, Alejandro Higuera-Matas, Gonzalo L. Montoya, María Luisa Soto-Montenegro, Juan José Vaquero, Manuel Desco
Publikováno v:
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
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Purpose: To analyze brain metabolic response to acute cocaine in male and female Wistar rats with or without a history of cannabinoid exposure during periadolescence. Procedures: The synthetic cannabinoid agonist CP 55,940 (CP) or its vehicle (VH), w