Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Carmen Diaz-Ruiz"'
Autor:
Aloia Quijano, Carmen Diaz-Ruiz, Andrea Lopez-Lopez, Begoña Villar-Cheda, Ana Muñoz, Ana I. Rodriguez-Perez, Jose L. Labandeira-Garcia
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 329 (2022)
The tissue renin–angiotensin system (RAS) has been shown to be involved in prooxidative and proinflammatory changes observed in aging and aging-related diseases such as dopaminergic degeneration in Parkinson’s disease (PD). We studied the activat
Externí odkaz:
https://doaj.org/article/bba0dc916a3b430fa3412779f6a057a2
Autor:
Aloia, Quijano, Carmen, Diaz-Ruiz, Andrea, Lopez-Lopez, Begoña, Villar-Cheda, Ana, Muñoz, Ana I, Rodriguez-Perez, Jose L, Labandeira-Garcia
Publikováno v:
Antioxidants (Basel, Switzerland). 11(2)
The tissue renin-angiotensin system (RAS) has been shown to be involved in prooxidative and proinflammatory changes observed in aging and aging-related diseases such as dopaminergic degeneration in Parkinson's disease (PD). We studied the activation
Autor:
Maria Garcia-Garrote, Begoña Villar-Cheda, Andrea López-López, Jose L. Labandeira-Garcia, Pablo Garrido-Gil, Aloia Quijano, Carmen Diaz-Ruiz, Ana Muñoz
Publikováno v:
Antioxidants
Antioxidants, Vol 10, Iss 1340, p 1340 (2021)
Volume 10
Issue 9
Antioxidants, Vol 10, Iss 1340, p 1340 (2021)
Volume 10
Issue 9
Dysregulation of the tissue renin–angiotensin system (RAS) is involved in tissue oxidative and inflammatory responses. Among RAS components, renin, its precursor (pro)renin and its specific receptor (PRR) have been less investigated, particularly i
Autor:
Ana I. Rodriguez-Perez, Pablo Garrido-Gil, Ana Borrajo, Carmen Diaz-Ruiz, Jose L. Labandeira-Garcia
Publikováno v:
Oncotarget
The local renin-angiotensin system (RAS) and insulin-like growth factor 1 (IGF-1) have been involved in longevity, neurodegeneration and aging-related dopaminergic degeneration. However, it is not known whether IGF-1 and angiotensin-II (AII) activate
Autor:
Pablo Garrido-Gil, Jose L. Labandeira-Garcia, Maria J. Guerra, Begoña Villar-Cheda, Antonio Dominguez-Meijide, Carmen Diaz-Ruiz
Publikováno v:
The Journals of Gerontology: Series A.
Sirtuin 3 (SIRT3) and angiotensin play a major role in aging-related disorders. Both modulate oxidative stress and neurodegeneration. We investigated the interaction between SIRT3 and angiotensin II (AngII) in the dopaminergic system. Both in vivo an
Autor:
Jose L. Labandeira-Garcia, Maria A. Costa-Besada, Ana Muñoz, Andrea López-López, Clynton Lourenço Corrêa, Carmen Diaz-Ruiz
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 73(12)
Dysregulation of tissue renin-angiotensin system (RAS) is involved in oxidative and inflammatory processes observed in major aging-related diseases, including neurodegenerative diseases such as Parkinson's disease (PD). Physical exercise has benefici
Autor:
Jannette Rodriguez-Pallares, Jose L. Labandeira-Garcia, Ana I. Rodriguez-Perez, Daniel Beiroa, Carmen Diaz-Ruiz
Publikováno v:
Oncotarget
Local angiotensin II (AII) and sirtuin 1 (SIRT1) play a major role in the modulation of neuroinflammation, oxidative stress and aging-related dopaminergic vulnerability to damage. However, it is not known whether the modulation is related to reciproc
Dopamine modulates astroglial and microglial activity via glial renin-angiotensin system in cultures
Autor:
Jose L. Labandeira-Garcia, Carmen Diaz-Ruiz, Antonio Dominguez-Meijide, Maria J. Guerra, Ana I. Rodriguez-Perez
Publikováno v:
Brain, behavior, and immunity. 62
Dopamine is an immunomodulatory molecule that acts on immune effector cells both in the CNS and peripheral tissues. However, the role of changes in dopamine levels in the neuroinflammatory response is controversial. The local/paracrine renin-angioten
Autor:
Hanna Ksiezak-Reding, Jun Wang, Lap Ho, Giulio Maria Pasinetti, Ismael Santa-Maria, Carmen Diaz-Ruiz
Publikováno v:
Neurobiology of Aging. 33:1427-1439
Abnormal folding of the microtubule-associated protein tau leads to aggregation of tau into paired helical filaments (PHFs) and neurofibrillary tangles, the major hallmark of Alzheimer's disease (AD). We have recently shown that grape seed polyphenol
Autor:
Jose L. Labandeira-Garcia, Carmen Diaz-Ruiz, Belen Joglar, Maria J. Guerra, Juan A. Parga, Jannette Rodriguez-Pallares
Publikováno v:
Developmental Dynamics. 239:3247-3259
Reactive oxygen species signaling has been suggested to regulate stem cell development. In the present study, we treated neurospheres of rat mesencephalic precursors with inhibitors of the NADPH oxidase complex and mitochondrial ATP-sensitive potassi